Mark Cullen | |
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| Education | Yale University School of Medicine |
| Occupation | Physician |
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Mark Richard Cullen is a physician, scholar, and population health scientist known for his work in occupational medicine. As a professor at Yale and later Stanford University, his research focused on the social, environmental, behavioral and bio-medical determinants of morbidity and mortality in adults, with special emphasis on the role of workplace’in such matters.
Cullen attended Central High School in Philadelphia, Pennsylvania, graduating as valedictorian in 1967. He received his BA from Harvard College in 1971 and his MD from Yale University School of Medicine in 1976, and took post-graduate training in Internal Medicine and Clinical Epidemiology, both also at Yale. [1]
Cullen was a Professor of Medicine and Public Health and the founder/director of the Occupational and Environmental Medicine (OEM) at Yale University School of Medicine from 1981-2009. OEM hosted the first academic clinic for the study of occupational disease in the US, and the first post-doctoral fellowship to train future researchers. [2] [3] Early in his Yale career he focused on introducing concepts of clinical epidemiology into occupational and environmental medicine as a counterpart to the prevailing approaches of population epidemiology and animal toxicology, focusing on chemical and biologic hazards of the workplace. [4] [5] [6]
His efforts enabled him to develop an academic/private partnership with Alcoa Inc. In his role as Alcoa’s senior medical officer, he extended his research into the psychosocial causes of disease in the workforce, exploiting existing administrative data on 250,000 former and present employees. [7] In 2006, Cullen was awarded an NIA grant to develop a model of population determinants of chronic disease, disability and death, followed by additional funding to study how employees and their families use various social and health benefit options. [8] [9] [10] [11] [12] [13]
Cullen expanded his work globally in a series of sabbaticals. During his sabbatical in Zimbabwe in 1988 Cullen conducted an epidemiological study exploring the impact of chrysotile asbestos on respiratory tract injury and malignancy risks. [14] The work contributed to the recognition globally that chrysotile was a threat to health, equal in most ways to the other fiber types of asbestos. In Ecuador in 1993 he studied cottage manufacturing and horticulture, largely unregulated with rampant lead, mercury and pesticide poisoning. [15] In South Africa in 1997, he joined a government commission reviewing the training programs in occupational and environmental health, leading to establishment of a new curricular model based on the emerging experience in the US. [16] [17]
In 2009 he joined Stanford University School of Medicine as Professor of Medicine and Chief of the Division of General Medical Disciplines. [18] He oversaw the transition of Stanford Hospital from a quaternary care hospital to a broad medical system.
In 2015 Cullen founded the Center for Population Health Sciences (PHS) whose mission is to improve the health of populations by bringing together diverse disciplines and data to understand and address social, environmental, behavioral, and biological determinants. [19] [20] [21] PHS allows scholars from diverse disciplines to easily and securely share, link, and analyze large disparate population-level datasets (including high risk data), facilitating a shift toward multi-disciplinary team science. The Center has 2,000 members and hosts 150 datasets. [22]
Cullen joined the faculties of Biomedical Data Science and Epidemiology, and was appointed a senior fellow of the Stanford Institute for Economic Policy Research. He also served as the Senior Associate Dean of Research for the School of Medicine (2016–19) and Senior Associate Vice Provost for Research at the University (2018–19). [23]
Cullen has published in many medical and scientific journals and co-edited the Textbook of Clinical Occupational and Environmental Medicine. [24]
Cullen is married to Michele Barry, MD FACP, Director of the Center for Innovation in Global Health at Stanford. They have two children, Zoe B. Cullen and Esme B. Cullen, and three grandchildren. [25] [26] Zoe is a labor economist and Assistant Professor of Business Administration at Harvard Business School, [27] and Esme is an internist and public health researcher. [28]
Multiple chemical sensitivity (MCS), also known as idiopathic environmental intolerances (IEI), is an unrecognized and controversial diagnosis characterized by chronic symptoms attributed to exposure to low levels of commonly used chemicals. Symptoms are typically vague and non-specific. They may include fatigue, headaches, nausea, and dizziness.
An epidemic is the rapid spread of disease to a large number of hosts in a given population within a short period of time. For example, in meningococcal infections, an attack rate in excess of 15 cases per 100,000 people for two consecutive weeks is considered an epidemic.
Epidemiology is the study and analysis of the distribution, patterns and determinants of health and disease conditions in a defined population.
A firefighter is a first responder trained in firefighting, primarily to control and extinguish fires that threaten life and property, as well as to rescue persons from confinement or dangerous situations. Male firefighters are sometimes referred to as firemen.
Environmental health is the branch of public health concerned with all aspects of the natural and built environment affecting human health. In order to effectively control factors that may affect health, the requirements that must be met in order to create a healthy environment must be determined. The major sub-disciplines of environmental health are environmental science, toxicology, environmental epidemiology, and environmental and occupational medicine.
A cancer registry is a systematic collection of data about cancer and tumor diseases. The data are collected by Cancer Registrars. Cancer Registrars capture a complete summary of patient history, diagnosis, treatment, and status for every cancer patient in the United States, and other countries.
Sir William Richard Shaboe Doll was a British physician who became an epidemiologist in the mid-20th century and made important contributions to that discipline. He was a pioneer in research linking smoking to health problems. With Ernst Wynder, Bradford Hill and Evarts Graham, he was credited with being the first to prove that smoking increased the risk of lung cancer and heart disease.
Community health refers to simple health services that are delivered by laymen outside hospitals and clinics. Community health is also the subset of public health that is taught to and practiced by clinicians as part of their normal duties. Community health volunteers and community health workers work with primary care providers to facilitate entry into, exit from and utilization of the formal health system by community members.
Social medicine is an interdisciplinary field that focuses on the profound interplay between socio-economic factors and individual health outcomes. Rooted in the challenges of the Industrial Revolution, it seeks to:
John P. A. Ioannidis is a Greek-American physician-scientist, writer and Stanford University professor who has made contributions to evidence-based medicine, epidemiology, and clinical research. Ioannidis studies scientific research itself, meta-research primarily in clinical medicine and the social sciences.
Miquel Porta is a Catalan physician, epidemiologist and scholar. He has promoted the integration of biological, clinical and environmental knowledge and methods in health research and teaching, which he has conducted internationally; notably, in Spain, at the University of North Carolina at Chapel Hill, Harvard, Imperial College London, and several other universities in Europe, North America, Kuwait, and Brazil. Appointed by the International Epidemiological Association (IEA), in 2008 he succeeded the Canadian epidemiologist John M. Last as Editor of "A Dictionary of Epidemiology". In the Preface to this book he argues for an inclusive and integrative practice of the science of epidemiology. In September 2023, Porta made public through several social networks a call to suggest changes to the new, 7th. edition of the dictionary. The deadline for such contributions is 30 November 2023.
Health effects of pesticides may be acute or delayed in those who are exposed. Acute effects can include pesticide poisoning, which may be a medical emergency. Strong evidence exists for other, long-term negative health outcomes from pesticide exposure including birth defects, fetal death, neurodevelopmental disorder, cancer, and neurologic illness including Parkinson's disease. Toxicity of pesticides depend on the type of chemical, route of exposure, dosage, and timing of exposure.
Nutritional epidemiology examines dietary and nutritional factors in relation to disease occurrence at a population level. Nutritional epidemiology is a relatively new field of medical research that studies the relationship between nutrition and health. It is a young discipline in epidemiology that is continuing to grow in relevance to present-day health concerns. Diet and physical activity are difficult to measure accurately, which may partly explain why nutrition has received less attention than other risk factors for disease in epidemiology. Nutritional epidemiology uses knowledge from nutritional science to aid in the understanding of human nutrition and the explanation of basic underlying mechanisms. Nutritional science information is also used in the development of nutritional epidemiological studies and interventions including clinical, case-control and cohort studies. Nutritional epidemiological methods have been developed to study the relationship between diet and disease. Findings from these studies impact public health as they guide the development of dietary recommendations including those tailored specifically for the prevention of certain diseases, conditions and cancers. It is argued by western researchers that nutritional epidemiology should be a core component in the training of all health and social service professions because of its increasing relevance and past successes in improving the health of the public worldwide. However, it is also argued that nutritional epidemiological studies yield unreliable findings as they rely on the role of diet in health and disease, which is known as an exposure that is susceptible to considerable measurement error.
The exposome is a concept used to describe environmental exposures that an individual encounters throughout life, and how these exposures impact biology and health. It encompasses both external and internal factors, including chemical, physical, biological, and social factors that may influence human health.
Sleep epidemiology is an emerging branch of the discipline of epidemiology. It is a growing field of scientific enquiry, with the first documented modern epidemiological survey being conducted in 1979.
Anne B. Newman is an American scientist who researches epidemiology and gerontology. She received her Bachelor's, Master's and M.D. degrees from the University of Pittsburgh. Newman's primary focus of study is on atherosclerosis, longevity and what specific factors allow for people to thrive while aging. She focuses on geriatrics, gerontology and epidemiology. She was the first scholar to be awarded the Katherine M. Detre Endowed Chair of Population Health Science at the University of Pittsburgh. She has been listed on the annual ISI Web of Knowledge most highly cited scientists for 2015, as published by Thomson Reuters. Newman is a member of the Delta Omega Honor Society in Public Health and the American Epidemiology Society. Newman's highest qualifications are in geriatric medicine and her certification is through the American Board of Internal Medicine. Newman lives in Point Breeze Pennsylvania with her husband, Frank Kirkwood. She is a mother of three.
Occupational cardiovascular diseases (CVD) are diseases of the heart or blood vessels caused by working conditions, making them a form of occupational illness. These diseases include coronary heart disease, stroke, cardiomyopathy, arrythmia, and heart valve or heart chamber problems. Cardiovascular disease is the leading cause of death in the United States and worldwide. In the United States, cardiovascular diseases account for one out of four deaths. The 6th International Conference on Work Environment and Cardiovascular Diseases found that within the working age population about 10-20% of cardiovascular disease deaths can be attributed to work. Ten workplace stressors and risk factors were estimated to be associated with 120,000 U.S. deaths each year and account for 5-8% of health care costs.
John Brownstein is a Canadian epidemiologist and Professor of Medicine at the Harvard Medical School as well as the Chief Innovation Officer at Boston Children’s Hospital. His research focuses on development of computational methods in epidemiology for applications to public health also known as computational epidemiology or e-epidemiology He is also the founder of several global public health surveillance systems including HealthMap. He is most known for his work on global tracking of disease outbreaks.
Elizabeth Anne (Lianne) Sheppard is an American statistician. She specializes in biostatistics and environmental statistics, and in particular in the effects of air quality on health. She is a Professor of Environmental and Occupational Health Sciences and a Professor of Biostatistics in the University of Washington School of Public Health. In 2021, Dr. Sheppard was named to the Rohm & Haas Endowed Professorship of Public Health Sciences.
Frank Erwin Speizer is an American physician and epidemiologist, currently Professor of Environmental Health and Environmental Science at Harvard T.H. Chan School of Public Health, and Edward H. Kass Distinguished Professor of Medicine at Brigham and Women's Hospital, Harvard Medical School. He is best known for his work on two major epidemiological cohort studies: the Nurses' Health Study, which explored women's illnesses and health risk factors, and the Harvard Six Cities study, which definitively linked air pollution to higher death rates in urban areas.
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