Mark E. Josephson Professor | |
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Born | January 27, 1943 |
Died | January 11, 2017 81) | (age
Citizenship | United States |
Alma mater | Trinity College, Columbia University College of Physicians and Surgeons |
Known for | "Clinical Cardiac Electrophysiology: Techniques and Interpretations" authorship, "Wellens and Josephson Advanced ECG" course |
Title | Herman Dana Professor of Medicine at Harvard Medical School, Chief of Cardiology at Beth Israel Deaconess Medical Center, Director of Harvard-Thorndike Electrophysiology Institute and Arrhythmia Service |
Scientific career | |
Fields | Cardiac electrophysiology |
Institutions | Beth Israel Deaconess Medical Center, Harvard Medical School |
Mark E. Josephson (1943-2017) was an American cardiologist and writer, who was in the 1970s one of the American pioneers of the medical cardiology subspecialty of cardiac electrophysiology. His book titled Clinical Cardiac Electrophysiology: Techniques and Interpretations is widely acknowledged as the definitive treatment of the discipline. He served as Herman Dana Professor of Medicine at Harvard Medical School, director of the Harvard-Thorndike Electrophysiology Institute and Arrhythmia Service [1] and the chief of cardiology at Harvard University's Beth Israel Deaconess Medical Center in Boston. [2]
Josephson was a graduate of Trinity College in Connecticut [3] and subsequently went to medical school at Columbia University College of Physicians and Surgeons. He completed his residency training in Internal Medicine at Mount Sinai Hospital in New York City and his cardiology fellowship at the Perelman School of Medicine at the University of Pennsylvania. [4]
After spending two years as a research associate with Anthony Damato at the Staten Island Public Health Service Hospital, he published articles on the electrophysiologic basis and anatomic location of AV nodal reentry and map-guided subendocardial resection to cure ventricular tachycardia, a procedure Time dubbed "the Pennsylvania Peel" in honor of the Penn cardiology department's surgical innovation. [4] Josephson's work helped to transform electrophysiology from a research field to a powerful clinical discipline for treating patients. [1]
Josephson has published over 400 original journal articles and 200 book chapters and reviews and is the author of the textbook of clinical cardiac electrophysiology, Clinical Cardiac Electrophysiology: Techniques and Interpretations. [4] First published in 1979, the book has run to seven editions. [5]
Josephson worked closely over the years with European cardiac electrophysiology pioneer Hein Wellens, chief of cardiology emeritus at the University of Limburg in Maastricht, Netherlands. For over 30 years, they coached together at high-yield "How to Approach Complex Arrhythmias" course for cardiologists [6] and EP fellows. [7] In the 2000s, they initiated an advanced course "Intracardiac Unknowns" which was attended by most electrophysiology trainees in the USA for over 10 years.
Throughout his career Josephson won numerous awards. This includes the Career Achievement Award from the University of California San Francisco Medical School as well as the University Medal for Excellence from Columbia University as well as the Distinguished Teacher Award. He has been given the Pioneer Award in Cardiac Pacing and Electrophysiology from the Heart Rhythm Society. He also received the American Heart Association's Paul Dudley White Award and the Eugene Braunwald Academic Mentorship Award. [8] [9] [1]
Josephson and his wife, Joan, married in 1967 and remained married until her death in June 2016. They had two children. He died on January 11, 2017, from cancer, leaving behind two daughters: Rachael and Stephanie Josephsons. [10]
Cardiology is the study of the heart. Cardiology is a branch of medicine that deals with disorders of the heart and the cardiovascular system. The field includes medical diagnosis and treatment of congenital heart defects, coronary artery disease, heart failure, valvular heart disease, and electrophysiology. Physicians who specialize in this field of medicine are called cardiologists, a sub-specialty of internal medicine. Pediatric cardiologists are pediatricians who specialize in cardiology. Physicians who specialize in cardiac surgery are called cardiothoracic surgeons or cardiac surgeons, a specialty of general surgery.
Beth Israel Deaconess Medical Center (BIDMC) in Boston, Massachusetts is a teaching hospital of Harvard Medical School and one of the founding members of Beth Israel Lahey Health. It was formed out of the 1996 merger of Beth Israel Hospital and New England Deaconess Hospital. Among independent teaching hospitals, Beth Israel Deaconess Medical Center has ranked in the top three recipients of biomedical research funding from the National Institutes of Health. Research funding totals nearly $200 million annually. BIDMC researchers run more than 850 active sponsored projects and 200 clinical trials. The Harvard-Thorndike General Clinical Research Center, the oldest clinical research laboratory in the United States, has been located on this site since 1973.
Cardiac electrophysiology is a branch of cardiology and basic science focusing on the electrical activities of the heart. The term is usually used in clinical context, to describe studies of such phenomena by invasive (intracardiac) catheter recording of spontaneous activity as well as of cardiac responses to programmed electrical stimulation - clinical cardiac electrophysiology. However, cardiac electrophysiology also encompasses basic research and translational research components. Specialists studying cardiac electrophysiology, either clinically or solely through research, are known as cardiac electrophysiologists.
Paul Dudley White was an American physician and cardiologist. He was considered one of the leading cardiologists of his day, and a prominent advocate of preventive medicine.
Eugene Braunwald is an Austrian-born American cardiologist.
Clinical cardiac electrophysiology, is a branch of the medical specialty of cardiology concerned with the study and treatment of rhythm disorders of the heart. Cardiologists with expertise in this area are usually referred to as electrophysiologists. Electrophysiologists are trained in the mechanism, function, and performance of the electrical activities of the heart. Electrophysiologists work closely with other cardiologists and cardiac surgeons to assist or guide therapy for heart rhythm disturbances (arrhythmias). They are trained to perform interventional and surgical procedures to treat cardiac arrhythmia.
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Henrick Joan Joost Wellens, M.D., (1935–2020) was a Dutch cardiologist who is considered one of the founding fathers of clinical cardiac electrophysiology - a discipline which enables patients with cardiac arrhythmias to have catheter electrode mapping and ablation.
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Edmund Hiram Sonnenblick was an American medical researcher and cardiologist. His studies of the function of cardiac muscle cells during the 1960s shaped the basis of both cardiovascular physiology and the modern treatment of cardiovascular disease, making possible the development of ACE inhibitors. In 1962, he was credited as the first person to image the heart muscle under scientifically-controlled conditions using the electron microscope. Though Sonnenblick's ideas about the relationship between the structure and function of the human heart today constitute medical-scientific commonsense, they were utterly novel at the time.
Arthur Jay Moss was an American cardiologist.
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