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A capillary is a small blood vessel from 5 to 10 micrometres (μm) in diameter. Capillaries are composed of only the tunica intima, consisting of a thin wall of simple squamous endothelial cells. They are the smallest blood vessels in the body: they convey blood between the arterioles and venules. These microvessels are the site of exchange of many substances with the interstitial fluid surrounding them. Substances which cross capillaries include water, oxygen, carbon dioxide, urea, glucose, uric acid, lactic acid and creatinine. Lymph capillaries connect with larger lymph vessels to drain lymphatic fluid collected in the microcirculation.
The circulatory system, also called the cardiovascular system or the vascular system, is an organ system that permits blood to circulate and transport nutrients, oxygen, carbon dioxide, hormones, and blood cells to and from the cells in the body to provide nourishment and help in fighting diseases, stabilize temperature and pH, and maintain homeostasis.
Cerebrovascular disease includes a variety of medical conditions that affect the blood vessels of the brain and the cerebral circulation. Arteries supplying oxygen and nutrients to the brain are often damaged or deformed in these disorders. The most common presentation of cerebrovascular disease is an ischemic stroke or mini-stroke and sometimes a hemorrhagic stroke. Hypertension is the most important contributing risk factor for stroke and cerebrovascular diseases as it can change the structure of blood vessels and result in atherosclerosis. Atherosclerosis narrows blood vessels in the brain, resulting in decreased cerebral perfusion. Other risk factors that contribute to stroke include smoking and diabetes. Narrowed cerebral arteries can lead to ischemic stroke, but continually elevated blood pressure can also cause tearing of vessels, leading to a hemorrhagic stroke.
Lymph is the fluid that flows through the lymphatic system, a system composed of lymph vessels (channels) and intervening lymph nodes whose function, like the venous system, is to return fluid from the tissues to the central circulation. Interstitial fluid – the fluid between the cells in all body tissues – enters the lymph capillaries. This lymphatic fluid is then transported via progressively larger lymphatic vessels through lymph nodes, where substances are removed by tissue lymphocytes and circulating lymphocytes are added to the fluid, before emptying ultimately into the right or the left subclavian vein, where it mixes with central venous blood.
Endothelium is a single layer of squamous endothelial cells that line the interior surface of blood vessels, and lymphatic vessels. The endothelium forms an interface between circulating blood or lymph in the lumen and the rest of the vessel wall. Endothelial cells form the barrier between vessels and tissue and control the flow of substances and fluid into and out of a tissue.
The National Heart, Lung, and Blood Institute (NHLBI) is the third largest Institute of the National Institutes of Health, located in Bethesda, Maryland, United States. It is tasked with allocating about $3.6 billion in FY 2020 in tax revenue to advancing the understanding of the following issues: development and progression of disease, diagnosis of disease, treatment of disease, disease prevention, reduction of health care disparities within the American population, and advancing the effectiveness of the US medical system. NHLBI's Director is Gary H. Gibbons (2012–present).
The University of Texas Southwestern Medical Center is a public academic health science center in Dallas, Texas. With approximately 13,568 employees and 2,445 faculty and over 2.7 million outpatient visits per year, UT Southwestern is the largest medical school in the University of Texas System and state of Texas.
James Anthony "Jim" Pawelczyk is an American researcher of physiology and Kinesiology who flew aboard the NASA STS-90 Space Shuttle mission as a Payload Specialist.
The lymphatic vessels are thin-walled vessels (tubes) structured like blood vessels, that carry lymph. As part of the lymphatic system, lymph vessels are complementary to the cardiovascular system. Lymph vessels are lined by endothelial cells, and have a thin layer of smooth muscle, and adventitia that binds the lymph vessels to the surrounding tissue. Lymph vessels are devoted to the propulsion of the lymph from the lymph capillaries, which are mainly concerned with absorption of interstitial fluid from the tissues. Lymph capillaries are slightly larger than their counterpart capillaries of the vascular system. Lymph vessels that carry lymph to a lymph node are called afferent lymph vessels, and those that carry it from a lymph node are called efferent lymph vessels, from where the lymph may travel to another lymph node, may be returned to a vein, or may travel to a larger lymph duct. Lymph ducts drain the lymph into one of the subclavian veins and thus return it to general circulation.
Angiology is the medical specialty dedicated to studying the circulatory system and of the lymphatic system, i.e., arteries, veins and lymphatic vessels.
Vascular disease is a class of diseases of the blood vessels – the arteries and veins of the circulatory system of the body. It is a subgroup of cardiovascular disease. Disorders in this vast network of blood vessels, can cause a range of health problems which can be severe or prove fatal.
Axel Ullrich is a German cancer researcher and has been the director of the molecular biology department at the Max Planck Institute of Biochemistry in Martinsried, Germany since 1988. This department's research has primarily focused on signal transduction. Ullrich has received Hamdan Award for Medical Research Excellence, awarded by Sheikh Hamdan bin Rashid Al Maktoum Award for Medical Sciences, Dubai, United Arab Emirates in 2008 and Ullrich and his team received the Wolf Prize in 2010.
Sree Chitra Tirunal Institute for Medical Sciences & Technology (SCTIMST), Trivandrum, is an Institution of National Importance established by an Act of Parliament in 1980. It is under the Department of Science and Technology, Government of India, with an Institute Body and a Governing Body constituted as per the provisions of the Sree Chitra Tirunal Institute for Medical Sciences & Technology, Trivandrum, Act, 1980. The Institute presents a unique model by connecting the different strands of Clinical Medicine, Biomedical Technology and Public Health to produce a seamless continuum of indisputable relevance to society.
Elizabeth Nabel is an American cardiologist and the current Executive Vice President of Strategy at ModeX Therapeutics in Natick, Massachusetts. Prior to this role, she served as President of Brigham Health and its Brigham and Women's Hospital, Professor of Medicine at Harvard Medical School, and Director of the NIH's National Heart, Lung, and Blood Institute.
Lymphatic vessel endothelial hyaluronan receptor 1 (LYVE1), also known as extracellular link domain containing 1 (XLKD1) is a Link domain-containing hyaladherin, a protein capable of binding to hyaluronic acid (HA), homologous to CD44, the main HA receptor. In humans it is encoded by the LYVE1 gene.
A vascular malformation, is a blood vessel or lymph vessel abnormality. Vascular malformations are one of the classifications of vascular anomalies, the other grouping is vascular tumors. They may cause aesthetic problems as they have a growth cycle, and can continue to grow throughout life.
The Leducq Foundation is a private foundation based in Paris, France. Its mission is to improve human health through international efforts to combat cardiovascular and neurovascular disease.
Rhian Merry Touyz Koppel is a South African medical researcher. She is the Assistant Director of the Institute of Cardiovascular and Medical Sciences (ICAMS), University of Glasgow, and the Vice-President of the International Society of Hypertension.
The North American Vascular Biology Organization is a scientific society promoting knowledge exchange in the area of vascular biology. The society organises several international scientific meetings annually which broadly cover the areas of development of blood and lymphatic vasculature, cardiovascular and lymphatic disease, vascular matrix biology and vascular bioengineering.
Karina Yaniv is an Israeli scientist who is best known for her contributions to the field of vascular development. She is a Professor of Vascular Disease in the Department of Biological Regulation at the Weizman Institute of science, Rehovot, Israel. She has three kids, and lives in the Weizmann Institute.
References
 | Scholia has an author profile for Mark L. Kahn . |
- 1 2 "Mark L. Kahn - Faculty Biosketch". www.med.upenn.edu. Retrieved 2021-10-26.
- ↑ "Penn Researcher Receives $6 Million Grant from Fondation Leducq for Lymphatic Vascular Study - Penn Medicine". www.pennmedicine.org. Retrieved 2021-10-26.
- ↑ "Researchers connect brain blood vessel lesions to intestinal bacteria". National Institutes of Health (NIH). 2017-05-18. Retrieved 2021-10-26.
- ↑ "The American Society for Clinical Investigation" . Retrieved 2021-10-27.
