Matthew C. Keller

Last updated
Matthew C. Keller
NationalityAmerican
Education University of Texas at Austin
University of Michigan
Scientific career
Fields Behavioral genetics
Institutions University of Colorado Boulder
Thesis Natural selection and the manifestations of low mood and depression  (2004)
Doctoral advisor Randolph M. Nesse
Website www.matthewckeller.com

Matthew C. Keller is an American behavioral and psychiatric geneticist. He is the Director of the Institute for Behavioral Genetics and a professor in the Department of Psychology and Neuroscience at the University of Colorado Boulder. [1] He is known for his criticism of the candidate gene approach [2] [3] [4] and for development of approaches in quantitative genetics. [5] [6]

References

  1. "Matthew C Keller's Home Page". www.matthewckeller.com. Retrieved 19 February 2019.
  2. Duncan, Laramie E.; Keller, Matthew C. (November 2011). "A Critical Review of the First 10 Years of Candidate Gene-by-Environment Interaction Research in Psychiatry". American Journal of Psychiatry. 168 (10): 1041–1049. doi:10.1176/appi.ajp.2011.11020191. ISSN   0002-953X. PMC   3222234 . PMID   21890791.
  3. Border, Richard; Johnson, Emma C.; Evans, Luke M.; Smolen, Andrew; Berley, Noah; Sullivan, Patrick F.; Keller, Matthew C. (May 2019). "No Support for Historical Candidate Gene or Candidate Gene-by-Interaction Hypotheses for Major Depression Across Multiple Large Samples". American Journal of Psychiatry. 176 (5): 376–387. doi:10.1176/appi.ajp.2018.18070881. ISSN   0002-953X. PMC   6548317 . PMID   30845820.
  4. Johnson, Emma C.; Border, Richard; Melroy-Greif, Whitney E.; de Leeuw, Christiaan A.; Ehringer, Marissa A.; Keller, Matthew C. (November 2017). "No Evidence That Schizophrenia Candidate Genes Are More Associated With Schizophrenia Than Noncandidate Genes". Biological Psychiatry. 82 (10): 702–708. doi:10.1016/j.biopsych.2017.06.033. PMC   5643230 . PMID   28823710.
  5. Haplotype Reference Consortium; Evans, Luke M.; Tahmasbi, Rasool; Vrieze, Scott I.; Abecasis, Gonçalo R.; Das, Sayantan; Gazal, Steven; Bjelland, Douglas W.; de Candia, Teresa R.; Goddard, Michael E.; Neale, Benjamin M. (May 2018). "Comparison of methods that use whole genome data to estimate the heritability and genetic architecture of complex traits". Nature Genetics. 50 (5): 737–745. doi:10.1038/s41588-018-0108-x. ISSN   1061-4036. PMC   5934350 . PMID   29700474.
  6. Keller, Matthew C. (January 2014). "Gene × Environment Interaction Studies Have Not Properly Controlled for Potential Confounders: The Problem and the (Simple) Solution". Biological Psychiatry. 75 (1): 18–24. doi:10.1016/j.biopsych.2013.09.006. PMC   3859520 . PMID   24135711.