On June 27,2021,Kranick was promoted to the major leagues to make his MLB debut as the starting pitcher versus the St. Louis Cardinals.[10] He threw five perfect innings,striking out three batters,before a rain delay occurred and he was removed.[11][12] He set the record for the most batters retired to begin a major league career with 15.[13] Over nine starts with the Pirates,Kranick went 2–3 with a 6.28 ERA and 32 strikeouts over 38+2⁄3 innings.[14]
Kranick opened the 2022 season with Indianapolis before he underwent Tommy John surgery in early June, forcing him out indefinitely.[15] He was activated from the injured list on September 1, 2023,[16] but did not appear in the majors for Pittsburgh. On January 5, 2024, Kranick was designated for assignment by the Pirates.[17]
New York Mets
On January 12, 2024, Kranick was claimed off waivers by the New York Mets.[18] After beginning the year on the injured list, he made 6 starts split between the Single–A St. Lucie Mets, Double–A Binghamton Rumble Ponies, and Triple–A Syracuse Mets, accumulating a 4.30 ERA with 13 strikeouts across 14+2⁄3 innings pitched. On May 6, Kranick was designated for assignment by the Mets.[19] He cleared waivers and was sent outright to Syracuse on May 11.[20] He had his contract selected back to the major league roster again on October 1.[21]
Kranick was named to the Mets' Opening Day roster for the 2025 season.[22]
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