Michael G. Hanna

Last updated

Michael Hanna
Born
Michael G. Hanna

1963 (age 59–60)
Leeds, Yorkshire, England
Alma mater University of Manchester
Scientific career
Institutions University College London
Thesis Studies on the molecular genetics and molecular pathogenesis of the mitochondrial encephalomyopathies  (1996)
Website orcid.org/0000-0003-0825-4075

Michael G Hanna (born 1963 in Leeds, England) is Director of the UCL Institute of Neurology, University College London and professor in clinical neurology and consultant neurologist at the National Hospital for Neurology and Neurosurgery, Queen Square, London, and also Director of the Medical Research Council (MRC) Centre for Neuromuscular Disease. [1] [2] [3] [4] [5]

Contents

Education

Hanna attended Lawnswood comprehensive state high school in Leeds and undertook undergraduate training in medical biochemistry and then medicine at the University of Manchester graduating with honours in 1988.

Career and research

He undertook postgraduate medical and neurological training at the Newcastle upon Tyne university teaching hospitals and at the John Radcliffe Hospital in Oxford and at the National Hospital for Neurology and Neurosurgery, Queen Square, London, London. He undertook neurological research training as an MRC clinical training fellow [6] at the UCL Institute of Neurology, National Hospital for Neurology and Neurosurgery, Queen Square, London.

Hanna was appointed consultant neurologist (neurology) to the National Hospital for Neurology and Neurosurgery, Queen Square, London, University College Hospital, NHS FT in 1998 and promoted to University College London professor of clinical neurology in 2006. He was clinical director of the National Hospital for Neurology and Neurosurgery from 2007-2012; the largest neurological disease hospital in the UK assessing over 130,000 patients per year. [7] He commenced as Director of the UCL Institute of Neurology, Queen Square, London in 2012. The UCL Institute of Neurology is the largest neurological research institute in the UK with over 1400 research staff and students and an annual turnover of £81m. In 2019 the institute held £261m in active research grants from external funders including MRC and Wellcome [8] [9]

Awards and achievements

National NHS England coordination of clinical services-in 2001 was central to setting up the NHS England Highly specialised service for rare neuromuscular diseases which continues successfully to this day coordinating 4 centres in London, Oxford and Newcastle enabling accurate diagnosis and treatment in congenital muscular dystrophy, congenital myasthenia, limb girdle dystrophy and muscle channelopathies.

In 2006 he was a founding partner to establish the NHS England Highly Specialised services for mitochondrial diseases linking Newcastle Oxford and London centres which continues successfully to this day.

In 2012 he led an audit across 10 NHS Trusts in the SE of England assessing over 700 patient episodes and provided evidence that 40% of unplanned emergency admissions for patients with Neuromuscular diseases were avoidable and would if extrapolated across the NHS would save >£40m per annum. He used this data to make a case with colleagues to set up a specialised Neuromuscular Complex Care Centre at UCLH and raised £2m through charity fund raising to build and open the NMCCC.

In 2008 Hanna established the MRC Centre for Translational Research in Neuromuscular Disease. [10] This has transformed the experimental medicine landscape in the UK for neuromuscular diseases and enabled many natural history studies and clinical trials. It established a National biobank of >5000 patient samples for research and has supported the training of over 34 clinical and non clinical PhD students.

Hanna established and is Director of a new MRC International Centre for Genomic Medicine in Neuromuscular Diseases in 2019. This £5.5m strategic award links 14 centres in India, Turkey, South Africa, Zambia and Brazil to advance genomics for patients and establish an international fellowship training programme.

He was voted best clinical teacher by clinical medical students year 2000. [11]

He has delivered many keynote lectures and memorial lectures worldwide including the UK, (Goulstonian Lectureship to the Royal College of Physicians in 2003 Goulstonian Lectures), and the prestigious Ian MacDonald Lecture. [12] [13]

He was elected a Guarantor of Brain in 2009, [14] and a corresponding member of the American Neurology Association in 2010. [15] [16]

He delivered the Inaugural Chopra Oration to the Indian Academy of Neurology in Hyderabad in 2019.

He was elected to the Fellowship of the Academy of Medical Sciences (FMedSci) in 2019.

Related Research Articles

Angela Vincent is Emeritus professor at the University of Oxford and a Fellow of Somerville College, Oxford.

<span class="mw-page-title-main">Neurology</span> Medical specialty dealing with disorders of the nervous system

Neurology is the branch of medicine dealing with the diagnosis and treatment of all categories of conditions and disease involving the nervous system, which comprises the brain, the spinal cord and the peripheral nerves. Neurological practice relies heavily on the field of neuroscience, the scientific study of the nervous system.

<span class="mw-page-title-main">National Hospital for Neurology and Neurosurgery</span> Hospital in London, England

<span class="mw-page-title-main">Institute of Psychiatry, Psychology and Neuroscience</span> Research institution in London, England

The Institute of Psychiatry, Psychology and Neuroscience (IoPPN) is a research institution dedicated to discovering what causes mental illness and diseases of the brain. In addition, its aim is to help identify new treatments for them and ways to prevent them in the first place. The IoPPN is a faculty of King's College London, England, previously known as the Institute of Psychiatry (IoP).

<span class="mw-page-title-main">Walton Centre</span> Neurological hospital in Liverpool, England

The Walton Centre, formerly known as the Walton Centre for Neurology and Neurosurgery, is a major neurology hospital located in the suburb of Fazakerley in the city of Liverpool, England. It is one of several specialist hospitals located within the Liverpool City Region alongside Liverpool Heart and Chest Hospital, Alder Hey Children's Hospital, Liverpool Women's Hospital, Mersey Regional Burns and Plastic Surgery Unit and Clatterbridge Cancer Centre. The wards in the hospital are all named after pioneering neurosurgeons in the 20th and 21st century. It is managed by the Walton Centre NHS Foundation Trust.

<span class="mw-page-title-main">Queen Square, London</span>

Queen Square is a garden square in the Bloomsbury district of central London. Many of its buildings are associated with medicine, particularly neurology.

University College London Hospitals NHS Foundation Trust (UCLH) is an NHS foundation trust based in London, United Kingdom. It comprises University College Hospital, University College Hospital at Westmoreland Street, the UCH Macmillan Cancer Centre, the Royal National ENT and Eastman Dental Hospitals, the Hospital for Tropical Diseases, the National Hospital for Neurology and Neurosurgery, the Royal London Hospital for Integrated Medicine and the Royal National Throat, Nose and Ear Hospital.

The Leslie Oliver Oration is held annually at the Queen's Hospital, London. The lectures are named after Leslie Oliver who founded the Neurosurgical Unit at Oldchurch Hospital in Essex in 1945. In addition, he was one of the early practitioners of functional neurosurgery in the United Kingdom, writing several articles on the surgical management of Parkinson’s disease.

The National Prion Clinic (UK) is part of the University College London Hospitals NHS Foundation Trust. Its aim is to diagnose and treat patients with any form of human prion disease (Creutzfeldt-Jakob disease, CJD). In addition, the clinic facilitates research in diagnostics and therapeutics, organises clinical trials, and counsels those with an increased genetic risk of the disease.

<span class="mw-page-title-main">Andrew Lees (neurologist)</span> UK neurologist (born 1947)

Andrew John Lees FRCP FRCP(G) FMedSci is Professor of Neurology at the National Hospital for Neurology and Neurosurgery, Queen Square, London and University College London. In 2011 he was named as the world's most highly cited Parkinson's disease researcher.

<span class="mw-page-title-main">UCL Queen Square Institute of Neurology</span> Academic institution in United Kingdom

The UCL Queen Square Institute of Neurology is an institute within the Faculty of Brain Sciences of University College London (UCL) and is located in London, United Kingdom. Together with the National Hospital for Neurology and Neurosurgery, an adjacent facility with which it cooperates closely, the institute forms a major centre for teaching, training and research in neurology and allied clinical and basic neurosciences.

<span class="mw-page-title-main">Sarah Tabrizi</span> British neurologist and neuroscientist

Sarah Joanna Tabrizi FMedSci is a British neurologist and neuroscientist in the field of neurodegeneration, particularly Huntington's disease. She is a Professor and Joint Head of the Department of Neurodegenerative Diseases at the UCL Institute of Neurology; the founder and Director of the UCL Huntington's Disease Centre; a Principal Investigator at the UK Dementia Research Institute at UCL; and an Honorary Consultant Neurologist at the National Hospital for Neurology and Neurosurgery, Queen Square, London, where she established the Multidisciplinary Huntington's Disease Clinic. The UCL Huntington’s Disease Centre was officially opened on 1 March 2017 by UCL President and Provost Professor Michael Arthur.

QS Enterprises Ltd in Queen Square, Central London is a wholly owned trading subsidiary of the University College London Hospitals Charity. It was the first health sector social enterprise of its kind in the United Kingdom and remains one of the few independent organisations working for the direct benefit of an NHS institution. Since 1985, QS Enterprises Ltd has donated in excess of £25 million to the Charity for the benefit of the hospitals that make up the University College London Hospitals NHS Foundation Trust.

<span class="mw-page-title-main">Dimitri Kullmann</span> British neurologist

Dimitri Michael Kullmann is a professor of neurology at the UCL Institute of Neurology, University College London (UCL), and leads the synaptopathies initiative funded by the Wellcome Trust. Kullmann is a member of the Queen Square Institute of Neurology Department of Clinical and Experimental Epilepsy and a consultant neurologist at the National Hospital for Neurology and Neurosurgery.

Mary M. Reilly FRCP is an Irish neurologist who works at National Hospital for Neurology and Neurosurgery. She studies peripheral neuropathy. She is the President of the Association of British Neurologists.

Sonia Gandhi is a British physician and neuroscientist who leads the Francis Crick Institute neurodegeneration laboratory. She holds a joint position at the UCL Queen Square Institute of Neurology. Her research investigates the molecular mechanisms that give rise to Parkinson's disease. During the COVID-19 pandemic, Gandhi was involved with the epidemiological investigations and testing efforts at the Francis Crick Institute.

Miratul Muqit FRSE FMedSci is a British neurologist and a Programme Lead at the MRC Protein Phosphorylation and Ubiquitylation Unit (MRCPPU) in the School of Life Sciences at the University of Dundee. His research focuses on the study of the PINK1 gene, mutations in which are a major cause of Parkinson's disease.

<span class="mw-page-title-main">Martin Rossor</span>

Martin Neil Rossor, is a British clinical neurologist with a specialty interest in degenerative dementias and familial disease.

Alan J. Thompson, MD, FMedSci, FRCP, FRCPI, is Dean of the Faculty of Brain Sciences at UCL; Pro-Provost for London at UCL; Garfield Weston Professor of Clinical Neurology and Neurorehabilitation at the UCL Queen Square Institute of Neurology. He is also a consultant neurologist at the University College London NHS Hospitals Foundation Trust working at the National Hospital for Neurology and Neurosurgery. He is Editor-in-Chief for Multiple Sclerosis Journal.

David John Werring is a British physician, neurologist, and academic specialising in stroke. He is professor of Neurology at the UCL Queen Square Institute of Neurology and current head of Stroke Research Centre and the department of Brain Repair & Rehabilitation at UCL.

References

  1. ↑ "Queen Square Centre for Neuromuscular Diseases". Cnmd.ac.uk. 3 October 2012. Retrieved 11 August 2015.
  2. ↑ "Mike Hanna". Cnmd.ac.uk. 3 October 2012. Retrieved 11 August 2015.
  3. ↑ Michael G. Hanna's publications indexed by the Scopus bibliographic database. (subscription required)
  4. ↑ Andreu, Antoni L.; Hanna, Hi Michael G.; Reichmann, Heinz; Bruno, Claudio; Penn, Audrey S.; Tanji, Kurenai; Pallotti, Francesco; Iwata, So; Bonilla, Eduardo; Lach, Boleslaw; Morgan-Hughes, John; Shanske, Sara; Sue, Carolyn M.; Pulkes, Teeratorn; Siddiqui, Asra; Clark, John B.; Land, John; Iwata, Momi; Schaefer, Jochen; DiMauro, Salvatore (1999). "Exercise Intolerance Due to Mutations in the CytochromebGene of Mitochondrial DNA". New England Journal of Medicine. 341 (14): 1037–1044. doi: 10.1056/NEJM199909303411404 . PMID   10502593.
  5. ↑ Jouvenceau, Anne; Eunson, Louise H; Spauschus, Alexander; Ramesh, Venkataswaran; Zuberi, Sameer M; Kullmann, Dimitri M; Hanna, Michael G (2001). "Human epilepsy associated with dysfunction of the brain P/Q-type calcium channel". The Lancet. 358 (9284): 801–807. doi:10.1016/S0140-6736(01)05971-2. PMID   11564488. S2CID   5698667.
  6. ↑ "Fellowships - Skills & careers - Medical Research Council". Mrc.ac.uk. 9 June 2015. Retrieved 11 August 2015.
  7. ↑ "Britain's best hospitals: A patients' guide - Features - Health & Families" . The Independent. 20 March 2008. Archived from the original on 12 May 2022. Retrieved 11 August 2015.
  8. ↑ "UCL Institute of Neurology". Ucl.ac.uk. Retrieved 11 August 2015.
  9. ↑ Horvath, R. (2006). "Phenotypic spectrum associated with mutations of the mitochondrial polymerase gene". Brain. 129 (7): 1674–1684. doi:10.1093/brain/awl088. PMID   16621917.
  10. ↑ "Queen Square Centre for Neuromuscular Diseases". Cnmd.ac.uk. 3 October 2012. Retrieved 11 August 2015.
  11. ↑ "Top Teacher and Administrator Awards 2010-11". Ucl.ac.uk. Retrieved 11 August 2015.
  12. ↑ "Professor Hanna invited to give prestigious ANZAN Lecture". Ucl.ac.uk. 8 April 2011. Retrieved 11 August 2015.
  13. ↑ "ANZAN". Archived from the original on 27 February 2015. Retrieved 22 June 2015.
  14. ↑ "Guarantors of Brain". Guarantors of Brain. Retrieved 11 August 2015.
  15. ↑ "American Neurological Association (ANA)". Myana.org. Retrieved 11 August 2015.
  16. ↑ Zuberi, S. M. (1999). "A novel mutation in the human voltage-gated potassium channel gene (Kv1.1) associates with episodic ataxia type 1 and sometimes with partial epilepsy". Brain. 122 (5): 817–825. doi: 10.1093/brain/122.5.817 . PMID   10355668.
This page is based on this Wikipedia article
Text is available under the CC BY-SA 4.0 license; additional terms may apply.
Images, videos and audio are available under their respective licenses.