Hysterectomy is the surgical removal of the uterus and cervix. Supracervical hysterectomy refers to removal of the uterus while the cervix is spared. These procedures may also involve removal of the ovaries (oophorectomy), fallopian tubes (salpingectomy), and other surrounding structures. The term “partial” or “total” hysterectomy are lay-terms that incorrectly describe the addition or omission of oophorectomy at the time of hysterectomy. These procedures are usually performed by a gynecologist. Removal of the uterus renders the patient unable to bear children and has surgical risks as well as long-term effects, so the surgery is normally recommended only when other treatment options are not available or have failed. It is the second most commonly performed gynecological surgical procedure, after cesarean section, in the United States. Nearly 68 percent were performed for conditions such as endometriosis, irregular bleeding, and uterine fibroids. It is expected that the frequency of hysterectomies for non-malignant indications will continue to fall given the development of alternative treatment options.
Gynecologic ultrasonography or gynecologic sonography refers to the application of medical ultrasonography to the female pelvic organs as well as the bladder, the adnexa, and the recto-uterine pouch. The procedure may lead to other medically relevant findings in the pelvis.This technique is useful to detect myomas or mullerian malformations.
An abdominal pregnancy is a rare type of ectopic pregnancy where the embryo or fetus is growing and developing outside the uterus, in the abdomen, and not in a fallopian tube, an ovary, or the broad ligament.
Placenta accreta occurs when all or part of the placenta attaches abnormally to the myometrium. Three grades of abnormal placental attachment are defined according to the depth of attachment and invasion into the muscular layers of the uterus:
- Accreta – chorionic villi attached to the myometrium, rather than being restricted within the decidua basalis.
- Increta – chorionic villi invaded into the myometrium.
- Percreta – chorionic villi invaded through the perimetrium.
A bicornuate uterus or bicornate uterus, is a type of müllerian anomaly in the human uterus, where there is a deep indentation at the fundus (top) of the uterus.
Camran Nezhat, FACOG, FACS is an American laparoscopic surgeon, reproductive endocrinology and infertility sub-specialist who has been teaching and practicing medicine and surgery as an adjunct clinical professor of surgery, and obstetrics and gynecology at Stanford University Medical Center in Palo Alto, California since 1993. Nezhat is also chair of the Association of the Adjunct Clinical Faculty, Stanford University School of Medicine, and a clinical professor of OB/GYN at the University of California, San Francisco.
Sarcoma botryoides or botryoid sarcoma is a subtype of embryonal rhabdomyosarcoma, that can be observed in the walls of hollow, mucosa lined structures such as the nasopharynx, common bile duct, urinary bladder of infants and young children or the vagina in females, typically younger than age 8. The name comes from the gross appearance of "grape bunches".
Fallopian tube obstruction, also known as fallopian tube occlusion, is a major cause of female infertility. Blocked fallopian tubes are unable to let the ovum and the sperm converge, thus making fertilization impossible.
Steven A. Vasilev is an American gynecologist, specializing in gynecologic oncology. He has served as Professor and Director of Integrative Medicine and Gynecologic Oncology at John Wayne Cancer Institute-Providence Saint John’s Health Center, Professor at John Wayne Cancer Institute in Santa Monica, California, and Professor at Loma Linda University School of Medicine faculty. Vasilev is a proponent of minimally invasive (laparoscopic) and robotic cancer surgery and complex pelvic surgery and has published research on medical and surgical therapies, integrative medicine, and screening for cervical cancer and human papilloma virus (HPV)
Percutaneous umbilical cord blood sampling (PUBS), also called cordocentesis, fetal blood sampling, or umbilical vein sampling is a diagnostic genetic test that examines blood from the fetal umbilical cord to detect fetal abnormalities. Fetal and maternal blood supply are typically connected in utero with one vein and two arteries to the fetus. The umbilical vein is responsible for delivering oxygen rich blood to the fetus from the mother; the umbilical arteries are responsible for removing oxygen poor blood from the fetus. This allows for the fetus’ tissues to properly perfuse. PUBS provides a means of rapid chromosome analysis and is useful when information cannot be obtained through amniocentesis, chorionic villus sampling, or ultrasound ; this test carries a significant risk of complication and is typically reserved for pregnancies determined to be at high risk for genetic defect. It has been used with mothers with immune thrombocytopenic purpura.
Primary fallopian tube cancer (PFTC), often just tubal cancer, is a malignant neoplasm that originates from the fallopian tube.
John Edmond Buster is an American physician who, while working at the University of California at Los Angeles School of Medicine, directed the research team that performed the first embryo transfer from one woman to another resulting in a live birth. It was performed at the Harbor-UCLA Medical Center, reported in July 1983, and culminated in the announcement of the birth on February 3, 1984. In the procedure, an embryo that was just beginning to develop was transferred from the woman in whom it had been conceived by artificial insemination to another woman who gave birth to the infant 38 weeks later. The sperm used in the artificial insemination came from the husband of the woman who bore the baby.
David A. Savitz is a professor of Community Health in the Epidemiology Section of the Program in Public Health, Vice President for Research, and Professor of Obstetrics and Gynecology, at The Alpert Medical School of Brown University, and Associate Director for Perinatal Research in The Department of Obstetrics and Gynecology at Women & Infants Hospital, both in Providence, Rhode Island. Savitz is the author of Interpreting epidemiologic evidence: strategies for study design and analysis (ISBN 0-19-510840-X) and more than 275 peer-reviewed articles. He was elected to the Institute of Medicine in 2007.
Robert J. Desnick is an American human geneticist whose basic and translational research accomplishments include significant discoveries in genomics, pharmacogenetics, gene therapy, personalized medicine, and the treatment of genetic diseases. His translational research has led to the development of the enzyme replacement therapy (ERT) and the chaperone therapy for Fabry disease, ERT for Niemann–Pick disease type B, and the RNA Interference Therapy for the Acute Hepatic Porphyrias.
Scott B. Ransom has worked across the healthcare ecosystem over 30 years as a physician, researcher, teacher, author, executive, strategy consultant and investor.
Peter James Taub, MD, FACS, FAAP, is an American Professor of Surgery, Pediatrics, Dentistry, Neurosurgery, and Medical Education at the Icahn School of Medicine at Mount Sinai as well as Attending Plastic and Reconstructive Surgeon at the Mount Sinai Medical Center and Elmhurst Hospital Center, all in New York City. He is a diplomate of both the American Board of Surgery and the American Board of Plastic Surgery.
Anne Barbara Michie Anderson was a Scottish reproductive physiologist, researcher, lecturer, and author. Her major contributions were for her research in reproductive physiology. In the last decade of her life, she broadened this to encompass more about women's health generally, including doing clinical trials and working with people focusing in on what would become evidence-based medicine.
Tubal factor infertility (TFI) is female infertility caused by diseases, obstructions, damage, scarring, congenital malformations or other factors which impede the descent of a fertilized or unfertilized ovum into the uterus through the fallopian tubes and prevents a normal pregnancy and full term birth. Tubal factors cause 25-30% of infertility cases. Tubal factor is one complication of chlamydia trachomatis infection in women.
Vaginal evisceration is an evisceration of the small intestine that occurs through the vagina, typically subsequent to vaginal hysterectomy, and following sexual intercourse after the surgery. It is a surgical emergency.
Ebony Carter is an obstetrician, reproductive health equity researcher and professor of obstetrics and gynecology at the University of North Carolina School of Medicine. Carter is the Director of the Division of Maternal-Fetal Medicine at University of North Carolina School of Medicine. As a physician-scientist, Carter is known for her research and implementation of community-based interventions to improve health equity among pregnant patients. Carter is the inaugural Associate Editor of Equity for the academic journal Obstetrics and Gynecology, published by the American College of Obstetricians and Gynecologists (ACOG).
