Lead poisoning, also known as plumbism and saturnism, is a type of metal poisoning caused by lead in the body. The brain is the most sensitive. Symptoms may include abdominal pain, constipation, headaches, irritability, memory problems, infertility, and tingling in the hands and feet. It causes almost 10% of intellectual disability of otherwise unknown cause and can result in behavioral problems. Some of the effects are permanent. In severe cases, anemia, seizures, coma, or death may occur.
Passive smoking is the inhalation of tobacco smoke, called secondhand smoke (SHS), or environmental tobacco smoke (ETS), by persons other than the intended "active" smoker. It occurs when tobacco smoke enters an environment, causing its inhalation by people within that environment. Exposure to secondhand tobacco smoke causes disease, disability, and death. The health risks of secondhand smoke are a matter of scientific consensus. These risks have been a major motivation for smoke-free laws in workplaces and indoor public places, including restaurants, bars and night clubs, as well as some open public spaces.
Preventive healthcare, or prophylaxis, consists of measures taken for the purposes of disease prevention. Disease and disability are affected by environmental factors, genetic predisposition, disease agents, and lifestyle choices, and are dynamic processes which begin before individuals realize they are affected. Disease prevention relies on anticipatory actions that can be categorized as primal, primary, secondary, and tertiary prevention.
The University of Rochester Medical Center (URMC), now known as UR Medicine, is located in Rochester, New York, is one of the main campuses of the University of Rochester and comprises the university's primary medical education, research and patient care facilities.
Blood lead level (BLL), is a measure of the amount of lead in the blood. Lead is a toxic heavy metal and can cause neurological damage, especially among children, at any detectable level. High lead levels cause decreased vitamin D and haemoglobin synthesis as well as anemia, acute central nervous system disorders, and possibly death.
Thiomersal is a mercury compound which is used as a preservative in some vaccines. Anti-vaccination activists promoting the incorrect claim that vaccination causes autism have asserted that the mercury in thiomersal is the cause. There is no scientific evidence to support this claim. The idea that thiomersal in vaccines might have detrimental effects originated with anti-vaccination activists and was sustained by them and especially through the action of plaintiffs' lawyers.
Herbert Leroy Needleman researched the neurodevelopmental damage caused by lead poisoning. He was a pediatrician, child psychiatrist, researcher and professor at the University of Pittsburgh, an elected member of the Institute of Medicine, and the founder of the Alliance to End Childhood Lead Poisoning. Dr. Needleman played a key role in securing some of the most significant environmental health protections achieved during the 20th century, which resulted in a fivefold reduction in the prevalence of lead poisoning among children in the United States by the early 1990s. Despite engendering strong resistance from lead-related industries, which made him the target of frequent attacks, Needleman persisted in campaigning to educate stakeholders, including parents and government panels, about the dangers of lead poisoning. Needleman has been credited with having played a key role in triggering environmental safety measures that have reduced average blood lead levels by an estimated 78 percent between 1976 and 1991. He died in Pittsburgh in 2017.
Sidestream smoke is smoke which goes into the air directly from a burning cigarette, cigar, or smoking pipe. Sidestream smoke is the main component of second-hand smoke (SHS), also known as Environmental Tobacco Smoke (ETS) or passive smoking. The relative quantity of chemical constituents of sidestream smoke are different from those of directly inhaled ("mainstream") smoke, although their chemical composition is similar. Sidestream smoke has been classified as a Class A carcinogen by the U.S. Environmental Protection Agency.
Philip John Landrigan, is an American epidemiologist and pediatrician and one of the world's leading advocates of children's health.
Based in Washington, D.C., Leadership for Healthy Communities is a $10-million national program of the Robert Wood Johnson Foundation designed to engage and support local and state government leaders nationwide in their efforts to advance public policies that support healthier communities and prevent childhood obesity. The program places an emphasis on policies with the greatest potential for increasing sustainable opportunities for physical activity and healthy eating among children at highest risk for obesity, including African-American, Latino, American Indian and Alaska Native, Asian-American and Pacific Islander children living in lower-income communities. The foundation's primary goal is the reversal of the childhood obesity epidemic by 2015.
Edwin Trevathan, an American child neurologist, pediatrician, epidemiologist, is the Amos Christie Chair in Global Health, Professor of Pediatrics and Neurology and Director of the Vanderbilt Institute for Global Health, Vanderbilt University Medical Center. He previously served as executive vice president and provost at Baylor University, following his work at the Saint Louis University College for Public Health and Social Justice, where he was dean and professor of epidemiology, pediatrics, and neurology. Previously he was director of the National Center on Birth Defects and Developmental Disabilities at the US Centers for Disease Control and Prevention (CDC) in Atlanta, Georgia. Before joining CDC in 2007, Trevathan was professor of neurology and pediatrics, as well as director of the Division of Pediatric & Developmental Neurology, at Washington University in St. Louis School of Medicine and was neurologist-in-chief at St. Louis Children's Hospital.
In analytical chemistry, biomonitoring is the measurement of the body burden of toxic chemical compounds, elements, or their metabolites, in biological substances. Often, these measurements are done in blood and urine. Biomonitoring is performed in both environmental health, and in occupational safety and health as a means of exposure assessment and workplace health surveillance.
Tobacco smoking during pregnancy causes many detrimental effects on health and reproduction, in addition to the general health effects of tobacco. A number of studies have shown that tobacco use is a significant factor in miscarriages among pregnant smokers, and that it contributes to a number of other threats to the health of the foetus.
Carol Remmer Angle is an American pediatrician, nephrologist, and toxicologist. Angle is known as one of the nation's leading researchers on lead poisoning. She is professor emeritus at the University of Nebraska Medical Center (UNMC) in Omaha, Nebraska. Angle joined UNMC in 1954 and was one of the first women to serve as chair of an academic medical department (pediatrics). She also served as chief of pediatric nephrology, director of the pediatric intensive care unit, and director of medical toxicology. In 1957, Angle along with Dr. Matilda McIntire, founded one of the country's first poison control centers. Angle is a founding member and a prior president of the American Association of Poison Control Centers. For forty years, Angle served as an expert for NIEHS, National Institutes of Health and U.S. Environmental Protection Agency panels investigating heavy metal toxicity. Angle continues as a toxicology consultant, reviewer and editor.
Childhood cancer is cancer in a child. About 80% of childhood cancer cases can be successfully treated thanks to modern medical treatments and optimal patient care. However, only about 10% of children diagnosed with cancer reside in high-income countries where the necessary treatments and care is available. Childhood cancer represents only about 1% of all types of cancers diagnosed in children and adults. For this reason, childhood cancer is often ignored in control planning, contributing to the burden of missed opportunities for its diagnoses and management in countries that are low- and mid-income.
Frank DeStefano FACPM is a medical epidemiologist and researcher at the Centers for Disease Control and Prevention, where he is director of the Immunization Safety Office.
Nadine Burke Harris is a Canadian-American pediatrician who has been the Surgeon General of California since 2019; she is the first person appointed to that position. She is known for linking adverse childhood experiences and toxic stress with harmful effects to health later in life. Hailed as a pioneer in the treatment of toxic stress, she is an advisory council member for the Clinton Foundation's "Too Small to Fail" campaign, and the founder and former chief executive officer of the Center for Youth Wellness. Her work was also featured in Paul Tough's book How Children Succeed.
The lead–crime hypothesis is a research area that involves a study of the correlation between elevated blood lead levels in children and increased rates of crime, delinquency, and recidivism later in life.
Mona Hanna-Attisha is a pediatrician, professor, and public health advocate whose research exposed the Flint water crisis. She is the author of the 2018 book What the Eyes Don't See, which The New York Times named as one of the 100 most notable books of the year.
Prasanna Nair is an Indian-born doctor working in the United States. She works in primary health care with a specialty in pediatric endocrinology
