MicroRNA 5680

MIR5680
Identifiers
Aliases	MIR5680 , microRNA 5680
External IDs	GeneCards: MIR5680
Gene location (Human) Chr. Chromosome 8 (human) [1] Band 8q22.3 Start 102,125,432 bp [1] End 102,125,515 bp [1]
RNA expression pattern Bgee Top expressed in right lung fundus minor salivary gland colon duodenum ovary More reference expression data BioGPS n/a
Orthologs
Species	Human	Mouse
Entrez	100847001	n/a
Ensembl	ENSG00000266756	n/a
UniProt	n a	n/a
RefSeq (mRNA)	n/a	n/a
RefSeq (protein)	n/a	n/a
Location (UCSC)	Chr 8: 102.13 – 102.13 Mb	n/a
PubMed search	[2]	n/a
Wikidata
View/Edit Human

MicroRNA 5680 is a protein that in humans is encoded by the MIR5680 gene. ^[3]

Function

microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop.

References

1. GRCh38: Ensembl release 89: ENSG00000266756 - Ensembl, May 2017
2. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
3. "Entrez Gene: MicroRNA 5680" . Retrieved 2016-05-09.

Further reading

This article incorporates text from the United States National Library of Medicine, which is in the public domain.