Munir Pirmohamed

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Professor Sir Munir Pirmohamed is a British clinical pharmacologist and geneticist. Since 2007 he has been the NHS Chair of Pharmacogenetics at the University of Liverpool.

Contents

Background

He attended the former St Paul’s School and Peterborough Technical College. [1]

Pirmohamed studied medicine at the University of Liverpool from 1980 to 1985. [2] He was awarded a PhD in pharmacology in 1993, and began working as a consultant physician at the Royal Liverpool University Hospital in 1996. [3] Pirmohamed gained the position of Personal Chair in Clinical Pharmacology at The University of Liverpool in 2001. [3] He went on to become the NHS Chair of Pharmacogenetics in 2007 and the David Weatherall Chair of Medicine at the University of Liverpool in 2013. [4] He was a member of the Commission on Human Medicines and chair of its Pharmacovigilance Expert Advisory Group from 2005 to 2020 and was appointed chair of the commission in 2021, [5]

He is Director of the Centre for Drug Safety Science, Director of the Wolfson Centre of Personalised Medicine, [6] and Director of the MRC Clinical Pharmacology Training Scheme, [7] all at the University of Liverpool. In addition, he is Director of HDR North, part of HDR UK. [8]

Alongside these responsibilities, Pirmohamed is a non-executive director for NHS England/Improvement, [9] a member of the governing council of the Medical Research Council, [10] a medical trustee for the British Heart Foundation, [11] and was president of the British Pharmacological Society from January 2020 to December 2021. [12] He is president-elect of the Association of Physicians for 2022, and will become president in 2023. [13]

In 2022, he chaired a committee that produced a report, Personalised prescribing, on behalf of the Royal College of Physicians of London and the British Pharmacological Society, which advocates the implementation of pharmacogenomics into the UK NHS. [14]

Research

Clinical Pharmacology, Pharmacogenetics and drug safety are the main areas of Pirmohamed's research. With a particular focus on adverse drug reactions, their role in improving prescription choices and the development of genetic tests for personalised medicine. He has published over 600 articles. [15] He is included the 2021 list of highly cited researchers by Clarivate, [16] and has been ranked number 1 expert in pharmacogenetics worldwide by Expertscape. [17]

Awards

Pirmohamed is an inaugural NIHR Senior Investigator and is a Fellow of the Academy of Medical Sciences. [6] Pirmohamed has received the William Withering Medal from the Royal College of Physicians and the IPIT award for Public Service from the University of North Carolina in the US. [18] and the Bionow Outstanding Contribution award for 2021. [19] He was knighted the in Queen's Birthday Honours in June 2015 for services to Medicine. [6]

Professional memberships

Funding

Pirmohamed has been awarded funding from The UK Department of Health, NIHR, MRC, Wellcome Trust, Wolfson Foundation, and the EU FP7 programme funds . [20]

Related Research Articles

<span class="mw-page-title-main">Pharmacogenomics</span> Study of the role of the genome in drug response

Pharmacogenomics, often abbreviated "PGx," is the study of the role of the genome in drug response. Its name reflects its combining of pharmacology and genomics. Pharmacogenomics analyzes how the genetic makeup of a patient affects their response to drugs. It deals with the influence of acquired and inherited genetic variation on drug response, by correlating DNA mutations with pharmacokinetic, pharmacodynamic, and/or immunogenic endpoints.

Pharmacotherapy, also known as pharmacological therapy or drug therapy, is defined as medical treatment that utilizes one or more pharmaceutical drugs to improve ongoing symptoms, treat the underlying condition, or act as a prevention for other diseases (prophylaxis).

<span class="mw-page-title-main">British Pharmacological Society</span> British society of pharmacologists

The British Pharmacological Society is the primary UK learned society for pharmacologists, concerned with research into drugs and the ways in which they work. Members work in academia, industry, regulatory agencies, and the health services, and many are medically qualified. The Society covers the whole spectrum of pharmacology, including laboratory, clinical, and toxicological aspects.

<span class="mw-page-title-main">Fellowship of Postgraduate Medicine</span> British non-profit organisation

The Fellowship of Postgraduate Medicine (FPM) is a British non-profit organisation that was founded after World War I and pioneered the development of postgraduate educational programmes in all branches of medicine. It was founded in late 1918 as the Inter-allied Fellowship of Medicine with Sir William Osler as its president. In the autumn of 1919, Osler merged the IAFM with the Postgraduate Medical Association of which he had been the founding President since 1911. In October 1919, Osler was appointed President of the combined Fellowship of Medicine and the Postgraduate Medical Association and Sir William Osler became the first president of the new organisation. The fellowship is supported by national and international fellows with expertise in the practice of medicine, medical education, clinical research, and related disciplines. The office and meeting rooms of the fellowship are in Central London. It is governed by a council that meets quarterly.

The National Institute for Health and Care Research (NIHR) is the British government's major funder of clinical, public health, social care and translational research. With a budget of over £1.2 billion in 2020–21, its mission is to "improve the health and wealth of the nation through research". The NIHR was established in 2006 under the government's Best Research for Best Health strategy, and is funded by the Department of Health and Social Care. As a research funder and research partner of the NHS, public health and social care, the NIHR complements the work of the Medical Research Council. NIHR focuses on translational research, clinical research and applied health and social care research.

Donald Robert James Singer was a British clinical pharmacologist who was the president of the Fellowship of Postgraduate Medicine.

<span class="mw-page-title-main">Derek Bell (physician)</span> Physician

Derek Bell was Professor of Acute Medicine at Imperial College London and continues to be an emeritus Professor. He has been a Consultant Physician at Central Middles Hospital, The Royal Infirmary of Edinburgh and most recently at Chelsea and Westminster Hospital NHS Foundation Trust. Appointed as the joint chair of two NHS Trusts in 2021. His initial leadership saw him and others receive parliamentary criticism. Professor Bell was the director of the National Institute for Health Research (NIHR) CLAHRC for Northwest London. He was President of the Royal College of Physicians of Edinburgh, elected in November 2013 he took office on 1 March 2014 succeeding Neil Dewhurst. He was re-elected for a second term on 24 November 2016. He was awarded an OBE in the 2018 New Year Honours for services to Unscheduled Care and Quality Improvement.

<span class="mw-page-title-main">Sam Ahmedzai</span> British care specialist

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Una Martin is an emeritus professor of clinical pharmacology and was formerly the deputy pro-vice chancellor for equalities at the University of Birmingham. She is an expert in hypertension and ambulatory monitoring. She is a Fellow of the British Pharmacological Society.

<span class="mw-page-title-main">Marc Tischkowitz</span> British medical geneticist

Marc Tischkowitz is a British medical geneticist. He is a Professor and Head of the Department of Medical Genetics at University of Cambridge. He also works as an Honorary NHS Consultant in the East Genomic Medicine Service. He is editor-in-chief of BJC Reports and NIHR CRN East of England Specialty Lead for Genetics. Tischkowitz researches Fanconi Anemia genes, hereditary cancer syndromes, and genomic technologies.

Russell Mardon Viner, FMedSci is an Australian-British paediatrician and policy researcher who is Chief Scientific Advisor at the Department for Education and Professor of Adolescent Health at the UCL Great Ormond Street Institute of Child Health. He is an expert on child and adolescent health in the UK and internationally. He was a member of the UK Government's Scientific Advisory Group for Emergencies (SAGE) during the COVID-19 pandemic and was President of the Royal College of Paediatrics and Child Health from 2018 to 2021. He remains clinically active, seeing young people with diabetes each week at UCL Hospitals. Viner is vice-chair of the NHS England Transformation Board for Children and Young People and Chair of the Stakeholder Council for the Board. He is a non-executive director (NED) at Great Ormond St. Hospital for Children NHS Foundation Trust, also sitting on the Trust's Finance & Investment and the Quality and Safety sub-committees.

David Christopher Crossman is a physician who has been the Dean of the University of St Andrews School of Medicine since 2014 and was the Chief Scientist (Health) within the Health and Social Care Directorates of the Scottish Government from 2017 to 2022.

<span class="mw-page-title-main">Martin Rossor</span>

Martin Neil Rossor is a British clinical neurologist with a specialty interest in degenerative dementias and familial disease.

Howard L. McLeod is an American pharmacogeneticist and implementation scientist specialized in precision medicine.

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Philip Michael Bath is a British clinician scientist. He is Stroke Association Professor of Stroke Medicine at the Stroke Trials Unit within the University of Nottingham. He specialises clinically in stroke and academically has established large-scale trials in treating and preventing stroke. Bath worked as a junior doctor before specialising in general medicine, stroke and hypertension. He is an Honorary Consultant Physician at Nottingham University Hospitals NHS Trust. He has spent his academic career at St George's, University of London, King's College London and University of Nottingham.

Patrick Francis Chinnery is a neurologist, clinician scientist, and Wellcome Trust Principal Research Fellow based in the Medical Research Council Mitochondrial Biology Unit and the University of Cambridge, where he is also professor of neurology and head of the department of clinical neurosciences.

Jean Gray is a Canadian academic and retired physician, who is professor emeritus of medical education, medicine and pharmacology at Dalhousie University. She has served as president of the Canadian and American Society of Clinical Pharmacology. She was invested as a Member of the Order of Canada in 2005, and has been a Fellow of the Royal College of Physicians since 2007. She was inducted into the Canadian Medical Hall of Fame in 2020.

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<span class="mw-page-title-main">Matthias Schwab (pharmacologist)</span> German pharmacologist

Matthias Schwab is a German doctor and university lecturer. He is director of the Dr. Margarete Fischer-Bosch-Institute of Clinical Pharmacology located on the campus of the Robert-Bosch-Hospital in Stuttgart, an institution of the Robert Bosch Stiftung, and holder of the Chair of Clinical Pharmacology at the University of Tübingen as well as Medical Director of the Department of Clinical Pharmacology at the University Hospital Tübingen.

References

  1. ↑ "Knighthood for former pupil".
  2. ↑ "Munir Pirmohamed". LinkedIn. Retrieved 4 March 2015.
  3. 1 2 "Pharmacologists in Phrame: Munir Pirmohamed". bps.ac.uk/. Retrieved 11 May 2022.
  4. ↑ "Munir Pirmohamed". linkedin.com. Retrieved 11 May 2022.
  5. ↑ "Press release: New Chair of the Commission on Human Medicines". gov.uk. Retrieved 11 May 2022.
  6. 1 2 3 "Professor Sir Munir Pirmohamed". ukri.org/. Retrieved 11 May 2022.
  7. ↑ "Contact us". liv.ac.uk. Retrieved 11 May 2022.
  8. ↑ "Health Data Research UK (HDRUK) North". hdruk.ac.uk/. Retrieved 11 May 2022.
  9. ↑ "Collaboration for Leadership in Applied Health Research and Care North West Coast". england.nhs.uk. Retrieved 11 May 2022.
  10. ↑ "Council Members". www.ukri.org/. Retrieved 11 May 2022.
  11. ↑ "Meet Our Board of Trustees". bhf.org.uk/. Retrieved 11 May 2022.
  12. ↑ "University professor announced as President Elect of the British Pharmacological Society". liverpool.ac.uk. Retrieved 11 May 2022.
  13. ↑ "Our People: Board of Trustees". aopgbi.org. Retrieved 11 May 2022.
  14. ↑ "Personalised prescribing: using pharmacogenomics to improve patient outcomes". rcp.ac.uk. Retrieved 11 May 2022.
  15. ↑ "Publons Munir Pirmohamed". publons.com/about/home/. Retrieved 11 May 2022.
  16. ↑ "Highly Cited researchers". clarivate.com/webofsciencegroup/. Retrieved 11 May 2022.
  17. ↑ "Expertise in Pharmacogenetics: Worldwide". expertscape.com/. Retrieved 11 May 2022.
  18. ↑ "Collaboration for Leadership in Applied Health Research and Care North West Coast". www.clahrc-nwc.nihr.ac.uk. Retrieved 4 March 2015.
  19. ↑ "Life Science Shines Brightly at the Bionow Digital Awards". bionow.co.uk/. Retrieved 11 May 2022.
  20. ↑ "Munir PIRMOHAMED, Research and Innovation". ec.europa.eu. Retrieved 4 March 2015.
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