 |
| NLPC-P60 | |
|---|---|
 Consensus secondary structure and sequence conservation of NLPC-P60 RNA | |
| Identifiers | |
| Symbol | NLPC-P60 |
| Rfam | RF03033 |
| Other data | |
| RNA type | Cis-reg |
| SO | SO:0005836 |
| PDB structures | PDBe |
The NLPC-P60 RNA motif is a conserved RNA structure that was discovered by bioinformatics. [1] NLPC-P60 motif RNAs are found in Streptomyces .
NLPC-P60 motif RNAs likely function as cis-regulatory elements, in view of their positions upstream of protein-coding genes. The RNAs are consistently located upstream of genes encoding examples of the conserved protein domain known as "NlpC/P60". The biochemical function of this domain is unknown, but it is found in lipoproteins. NlpC/P60 proteins have been related with plant-bacteria interactions. [2] Additionally, genes encoding this domain are often regulated by riboswitches that sense the signaling molecule cyclic di-AMP. However, no associated between the NLPC-P60 RNA motif and cyclic di-AMP has been established.