Natalia Gomez-Ospina

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Natalia Gomez-Ospina is a Colombian physician-scientist who studies genetic disorders and lysosomal storage disorders. [1] She was born in Medellín, Colombia. [2] She is an Assistant Professor of Pediatrics (Genetics) and of Pediatrics (Stem Cell Transplantation) at Stanford University and works at Lucile Packard Children's Hospital. [1] [2] She is a member of Stanford Bio-X. [3]

Contents

Natalia Gomez-Ospina
Born
Medellín, Colombia
Nationality Colombian
Alma mater National University of Colombia
University of Colorado Boulder
Known for Medical Genetics
Hematopoietic stem cell transplantation
Scientific career
Fields Pediatrics
Thesis The calcium channel CACNA1C gene: multiple proteins, diverse functions
Website https://www.gomezospina.com/

Education

Gomez-Ospina studied petroleum engineering at the National University of Colombia [4] before transferring to the University of Colorado Boulder, where she double-majored in Molecular, Cellular, and Developmental Biology and Biochemistry. [1] [2] [5] [6] She graduated summa cum laude . [5]

She joined the Medical Scientist Training Program at the Stanford University School of Medicine and earned her MD/PhD in 2011. [7] Her doctoral thesis was entitled, "The calcium channel CACNA1C gene: multiple proteins, diverse functions."

She spent a year in internal medicine at Santa Barbara Cottage hospital before pursuing a Dermatology residency at Johns Hopkins Hospital. [8] She completed her residency in Medical Genetics at Stanford Hospital. [9] Her post-doctoral work focused on hematopoietic stem cell transplantation in pediatrics. [3]

Research

Gomez-Ospina has published research in several academic journals, including The New England Journal of Medicine , [10] Cell, [11] Nature Communications , [12] Nature Medicine , [13] [14] and the American Journal of Medical Genetics . [2] [15]

Her professional work includes point-of-care testing for children with disorders in their ability to regulate ammonia levels. With her colleagues, Gomez-Ospina has developed a handheld device to measure levels of ammonia in serum. [16] [17] [18] [19]

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References

  1. 1 2 3 "Natalia Gomez-Ospina | Stanford Medicine Profiles". med.stanford.edu. Retrieved 2021-01-23.
  2. 1 2 3 4 "Natalia Gomez-Ospina's Profile | Stanford Profiles". profiles.stanford.edu. Retrieved 2021-01-23.
  3. 1 2 University, © Stanford; Stanford; California 94305 (2018-11-02). "Natalia Gomez-Ospina - Assistant Professor of Pediatrics (Genetics and Stem Cell Transplantation)". Welcome to Bio-X. Retrieved 2021-01-23.{{cite web}}: CS1 maint: numeric names: authors list (link)
  4. ↑ "Browsing by Author "Ospina Gómez, Natalia Andrea"". repositorio.unal.edu.co. Retrieved 2021-01-23.
  5. 1 2 "People". Gomez-Ospina Lab. Retrieved 2021-01-23.
  6. ↑ Fromherz, S. (2004-01-15). "Mutations in -tubulin promote basal body maturation and flagellar assembly in the absence of -tubulin". Journal of Cell Science. 117 (2): 303–314. doi: 10.1242/jcs.00859 . ISSN   0021-9533. PMID   14676280.
  7. ↑ "MSTP Alumni (before 2015)". MSTP MD-PhD Program. Retrieved 2021-01-23.
  8. ↑ "Dr. Natalia Gomez-Ospina, MD – Palo Alto, CA | Medical Genetics on Doximity". Doximity. Retrieved 2021-01-23.
  9. ↑ University, © Stanford; Stanford; California 94305 (2020-01-31). "Natalia Gomez-Ospina". Wu Tsai Neurosciences Institute. Retrieved 2021-01-23.{{cite web}}: CS1 maint: numeric names: authors list (link)
  10. ↑ Gomez-Ospina, Natalia; Chang, Anne Lynn S.; Qu, Kun; Oro, Anthony E. (2012-06-07). "Translocation Affecting Sonic Hedgehog Genes in Basal-Cell Carcinoma". New England Journal of Medicine. 366 (23): 2233–2234. doi:10.1056/nejmc1115123. ISSN   0028-4793. PMC   3839666 . PMID   22670922.
  11. ↑ Gomez-Ospina, Natalia; Tsuruta, Fuminori; Barreto-Chang, Odmara; Hu, Linda; Dolmetsch, Ricardo (Nov 2006). "The C Terminus of the L-Type Voltage-Gated Calcium Channel CaV1.2 Encodes a Transcription Factor". Cell. 127 (3): 591–606. doi:10.1016/j.cell.2006.10.017. PMC   1750862 . PMID   17081980.
  12. ↑ Gomez-Ospina, Natalia; Potter, Carol J.; Xiao, Rui; Manickam, Kandamurugu; Kim, Mi-Sun; Kim, Kang Ho; Shneider, Benjamin L.; Picarsic, Jennifer L.; Jacobson, Theodora A.; Zhang, Jing; He, Weimin (Apr 2014). "Mutations in the nuclear bile acid receptor FXR cause progressive familial intrahepatic cholestasis". Nature Communications. 7 (1): 10713. doi:10.1038/ncomms10713. ISSN   2041-1723. PMC   4759630 . PMID   26888176.
  13. ↑ Vakulskas, Christopher A.; Dever, Daniel P.; Rettig, Garrett R.; Turk, Rolf; Jacobi, Ashley M.; Collingwood, Michael A.; Bode, Nicole M.; McNeill, Matthew S.; Yan, Shuqi; Camarena, Joab; Lee, Ciaran M. (Aug 2018). "A high-fidelity Cas9 mutant delivered as a ribonucleoprotein complex enables efficient gene editing in human hematopoietic stem and progenitor cells". Nature Medicine. 24 (8): 1216–1224. doi:10.1038/s41591-018-0137-0. ISSN   1078-8956. PMC   6107069 . PMID   30082871.
  14. ↑ Charlesworth, Carsten T.; Deshpande, Priyanka S.; Dever, Daniel P.; Camarena, Joab; Lemgart, Viktor T.; Cromer, M. Kyle; Vakulskas, Christopher A.; Collingwood, Michael A.; Zhang, Liyang; Bode, Nicole M.; Behlke, Mark A. (Feb 2019). "Identification of preexisting adaptive immunity to Cas9 proteins in humans". Nature Medicine. 25 (2): 249–254. doi:10.1038/s41591-018-0326-x. ISSN   1078-8956. PMC   7199589 . PMID   30692695.
  15. ↑ Weiss, Karin; Terhal, Paulien A.; Cohen, Lior; Bruccoleri, Michael; Irving, Melita; Martinez, Ariel F.; Rosenfeld, Jill A.; Machol, Keren; Yang, Yaping; Liu, Pengfei; Walkiewicz, Magdalena (Oct 2016). "De Novo Mutations in CHD4, an ATP-Dependent Chromatin Remodeler Gene, Cause an Intellectual Disability Syndrome with Distinctive Dysmorphisms". The American Journal of Human Genetics. 99 (4): 934–941. doi:10.1016/j.ajhg.2016.08.001. PMC   5065651 . PMID   27616479.
  16. ↑ "Researchers develop a portable blood ammonia detector". EurekAlert!. Retrieved 2021-01-23.
  17. ↑ "Portable blood ammonia detector could be "life-changing"". New Atlas. 2020-07-22. Retrieved 2021-01-23.
  18. ↑ "Portable blood ammonia detector". ScienceDaily. Retrieved 2021-01-23.
  19. ↑ Kubota, Author Taylor (2020-07-24). "Device could help patients test blood ammonia levels at home". Scope. Retrieved 2021-01-23.{{cite web}}: |first= has generic name (help)
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