Nathaniel Dimsdale, FRS (11 April 1748 – 3 July 1811), a British physician and MP who received a Barony of the Russian Empire for his work in Russia on smallpox vaccination. [1]
He was the second son of the Quaker Thomas Dimsdale, a Hertfordshire physician, banker, and MP, and was educated at Eton School. After travelling with his father to St. Petersburg in 1768 to inoculate Catherine the Great and her son, Grand Duke Paul, against smallpox, he, along with his father, received an annuity and was created Baron Dimsdale of the Russian Empire. On his return, he studied medicine at the University of Edinburgh, graduating with an MB in 1771.
He returned to Russia with his father in 1781 to carry out further inoculations within the Russian royal family. He became a partner in the family bank of Baron Dimsdale, Sons, Barnard and Staples, established by his father. When his father retired in 1790, he succeeded to his father's Parliamentary seat for Hertford, holding it until 1802.
In 1805, he was elected a Fellow of the Royal Society. [2]
By then, he was not in good health and died on a trip for his health to Brighton in 1811. He was unmarried and left his estate to his sister, Ann Dimsdale. His barony lapsed on his death, but that of his father passed down in the family via his elder brother John.
Edward Jenner, was an English physician and scientist who pioneered the concept of vaccines and created the smallpox vaccine, the world's first vaccine. The terms vaccine and vaccination are derived from Variolae vaccinae, the term devised by Jenner to denote cowpox. He used it in 1798 in the title of his Inquiry into the Variolae vaccinae known as the Cow Pox, in which he described the protective effect of cowpox against smallpox.
Jan Ingenhousz or Ingen-Housz FRS was a Dutch-born British physiologist, biologist and chemist.
Earl Cowper was a title in the Peerage of Great Britain. It was created in 1718 by George I for William Cowper, 1st Baron Cowper, his first Lord Chancellor, with remainder in default of male issue of his own to his younger brother, Spencer Cowper. Cowper had already been created Baron Cowper of Wingham in the County of Kent, in the Peerage of England on 14 December 1706, with normal remainder to the heirs male of his body, and was made Viscount Fordwich, in the County of Kent, at the same time as he was given the earldom, also Peerage of Great Britain and with similar remainder. He was the great-grandson of William Cowper, who was created a Baronet, of Ratling Court in the County of Kent, in the Baronetage of England on 4 March 1642. The latter was succeeded by his grandson, the second Baronet. He represented Hertford in Parliament. He was succeeded by his eldest son, the aforementioned William Cowper, the third Baronet, who was elevated to the peerage as Baron Cowper in 1706 and made Earl Cowper in 1718. In 1706 Lord Cowper married as his second wife Mary Clavering, daughter of John Clavering, of Chopwell, County Durham.
Bengeo is a suburb and former village and civil parish on the north-west edge of the county town of Hertford in Hertfordshire, England. It is an electoral ward of Hertford. In 1891 the parish had a population of 2586. In 1894 the parish was abolished to form Bengeo Rural and Bengeo Urban.
Zabdiel Boylston, FRS was a physician in the Boston area. As the first medical school in North America was not founded until 1765, Boylston apprenticed with his father, an English-born surgeon named Thomas Boylston, and studied under the Boston physician Dr. Cutler. Boylston is known for holding several "firsts" for an American-born physician: he performed the first surgical operation by an American physician, the first removal of gall bladder stones in 1710, and the first removal of a breast tumor in 1718. He was also the first physician to perform smallpox inoculations in North America.
Alexander Monro was a Scottish surgeon and anatomist. His father, the surgeon John Monro, had been a prime mover in the foundation of the Edinburgh Medical School and had arranged Alexander's education in the hope that his son might become the first Professor of Anatomy in the new university medical school.
Joseph Adams, F.L.S. was a British physician and surgeon.
Prince Alfred of Great Britain was the fourteenth child and ninth and youngest son of King George III and his queen consort, Charlotte of Mecklenburg-Strelitz. In 1782, Alfred, who had never enjoyed robust health, became unwell after his inoculation against smallpox. His early death, along with that of his brother Prince Octavius six months later, deeply distressed the royal family. In his later bouts of madness, King George imagined conversations with both of his youngest sons.
James Jurin FRS FRCP was an English scientist and physician, particularly remembered for his early work in capillary action and in the epidemiology of smallpox vaccination. He was a staunch proponent of the work of Sir Isaac Newton and often used his gift for satire in Newton's defence.
The history of smallpox extends into pre-history. Genetic evidence suggests that the smallpox virus emerged 3,000 to 4,000 years ago. Prior to that, similar ancestral viruses circulated, but possibly only in other mammals, and possibly with different symptoms. Only a few written reports dating from about 500 AD to 1000 AD are considered reliable historical descriptions of smallpox, so understanding of the disease prior to that has relied on genetics and archaeology. However, during the 2nd millennium AD, especially starting in the 16th century, reliable written reports become more common. The earliest physical evidence of smallpox is found in the Egyptian mummies of people who died some 3,000 years ago. Smallpox has had a major impact on world history, not least because indigenous populations of regions where smallpox was non-native, such as the Americas and Australia, were rapidly and greatly reduced by smallpox during periods of initial foreign contact, which helped pave the way for conquest and colonization. During the 18th century the disease killed an estimated 400,000 Europeans each year, including five reigning monarchs, and was responsible for a third of all blindness. Between 20 and 60% of all those infected—and over 80% of infected children—died from the disease.
Robert Dimsdale was an English banker and Conservative politician who sat in the House of Commons in two periods between 1866 and 1892.
Essendon is a village and civil parish in Hertfordshire 6 miles (10 km), south-west of Hertford.
Robert Marsham, 1st Baron Romney of The Mote, Maidstone, known as Sir Robert Marsham, Bt between 1703 and 1716, was an English Whig politician who sat in the House of Commons from 1708 to 1716 when he was raised to the peerage as Baron Romney.
Variolation was the method of inoculation first used to immunize individuals against smallpox (Variola) with material taken from a patient or a recently variolated individual, in the hope that a mild, but protective, infection would result. Only 1–2% of those variolated died from the intentional infection compared to 30% who contracted smallpox naturally. Variolation is no longer used today. It was replaced by the smallpox vaccine, a safer alternative. This in turn led to the development of the many vaccines now available against other diseases.
Charles Maitland was a Scottish surgeon who inoculated people against smallpox.
Baron Thomas Dimsdale was an English doctor, banker and politician who sat in the House of Commons from 1780 to 1790. He was created Baron Dimsdale of the Russian Empire by Catherine the Great.
Inoculation is the act of implanting a pathogen or other microbe or virus into a person or other organism. It is a method of artificially inducing immunity against various infectious diseases. The term "inoculation" is also used more generally to refer to intentionally depositing microbes into any growth medium, as into a Petri dish used to culture the microbe, or into food ingredients for making cultured foods such as yoghurt and fermented beverages such as beer and wine. This article is primarily about the use of inoculation for producing immunity against infection. Inoculation has been used to eradicate smallpox and to markedly reduce other infectious diseases such as polio. Although the terms "inoculation", "vaccination", and "immunization" are often used interchangeably, there are important differences. Inoculation is the act of implanting a pathogen or microbe into a person or other recipient; vaccination is the act of implanting or giving someone a vaccine specifically; and immunization is the development of disease resistance that results from the immune system's response to a vaccine or natural infection.
Henry Brougham, FRSE, of Brougham Hall (1742–1810), was an important landowner in north west England whose estates extended throughout much of Westmorland.
Baron Dimsdale is a title which was conferred on the physician Thomas Dimsdale of Hertfordshire by the Russian Royal Family.