Neisseria sigma-E sRNA

Neisseria sigma-E sRNA
Neisseria sigma-E sRNA
	A representation of the Neisseria sigma-E sRNA secondary structure including a colour scheme that indicates the degree of sequence conservation.
Identifiers
Symbol	NSE_sRNA
Rfam	RF02270
Other data
RNA type	Gene
Domain	Bacteria;
PDB structures	PDBe

Last updated October 08, 2025

Neisseria sigma-E sRNA (NSE sRNA) is a non-coding RNA found in the bacterial genus Neisseria, including the two pathogens N. meningitidis and N. gonorrhoeae. The RNA was discovered in a screen for genes differentiated by high expression of the Sigma factor, sigma E.^[1] Seven genes were predicted to be regulated by NSE sRNA, including fur, nadC and a putative TetR family transcriptional regulator, through base-pairing interactions with the 5' UTR. The sRNA transcript is terminated by a rho independent terminator.

References

↑ Huis in 't Veld RA, Willemsen AM, van Kampen AH, Bradley EJ, Baas F, Pannekoek Y, van der Ende A (2011). Yang PC (ed.). "Deep sequencing whole transcriptome exploration of the σE regulon in Neisseria meningitidis". PLOS ONE. 6 (12) e29002. Bibcode:2011PLoSO...629002H. doi: 10.1371/journal.pone.0029002 . PMC 3240639 . PMID 22194974.

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[pmid22194974-1] Huis in 't Veld RA, Willemsen AM, van Kampen AH, Bradley EJ, Baas F, Pannekoek Y, van der Ende A (2011). Yang PC (ed.). "Deep sequencing whole transcriptome exploration of the σE regulon in Neisseria meningitidis". PLOS ONE. 6 (12) e29002. Bibcode:2011PLoSO...629002H. doi: 10.1371/journal.pone.0029002 . PMC 3240639 . PMID 22194974.

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