PRSS55

PRSS55
Identifiers
Aliases	PRSS55 , CT153, T-SP1, TSP1, UNQ9391, protease, serine 55, serine protease 55
External IDs	MGI: 1918287 HomoloGene: 51233 GeneCards: PRSS55
Gene location (Human)
Chr.	Chromosome 8 (human) [1]
End	10,554,166 bp [1]
Gene location (Mouse)
Chr.	Chromosome 14 (mouse) [2]
End	64,090,162 bp [2]
Gene ontology
Molecular function	• peptidase activity ; • serine-type peptidase activity ; • hydrolase activity ; • serine-type endopeptidase activity ;
Cellular component	• cytoplasm ; • integral component of membrane ; • cytosol ; • membrane ;
Biological process	• proteolysis ;
	Sources:Amigo / QuickGO
Orthologs
	203074
	71037
	ENSG00000184647 ; ENSG00000285141
	ENSMUSG00000034623
	Q6UWB4
	Q14BX2
	NM_001197020 ; NM_198464
	NM_001081063
	NP_001183949 ; NP_940866
	n/a
	Wikidata
View/Edit Human	View/Edit Mouse

Last updated June 26, 2019

Serine protease 55 is a protein that in humans is encoded by the PRSS55 gene. ^[5]

Protein Biological molecule consisting of chains of amino acid residues

Proteins are large biomolecules, or macromolecules, consisting of one or more long chains of amino acid residues. Proteins perform a vast array of functions within organisms, including catalysing metabolic reactions, DNA replication, responding to stimuli, providing structure to cells and organisms, and transporting molecules from one location to another. Proteins differ from one another primarily in their sequence of amino acids, which is dictated by the nucleotide sequence of their genes, and which usually results in protein folding into a specific three-dimensional structure that determines its activity.

In biology, a gene is a sequence of nucleotides in DNA or RNA that codes for a molecule that has a function. During gene expression, the DNA is first copied into RNA. The RNA can be directly functional or be the intermediate template for a protein that performs a function. The transmission of genes to an organism's offspring is the basis of the inheritance of phenotypic trait. These genes make up different DNA sequences called genotypes. Genotypes along with environmental and developmental factors determine what the phenotypes will be. Most biological traits are under the influence of polygenes as well as gene–environment interactions. Some genetic traits are instantly visible, such as eye color or number of limbs, and some are not, such as blood type, risk for specific diseases, or the thousands of basic biochemical processes that constitute life.

Function

This gene encodes a member of a group of membrane-anchored chymotrypsin (S1)-like serine proteases. The encoded protein is primarily expressed in the Leydig and Sertoli cells of the testis and may be involved in male fertility. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Sep 2010].

Related Research Articles

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Granzyme B is a serine protease that in humans is encoded by the GZMB gene. Granzyme B is expressed by cytotoxic T lymphocytes (CTL) and natural killer (NK) cells.

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Chymotrypsin-like elastase family member 3A is an enzyme that in humans is encoded by the CELA3A gene.

WAP, kazal, immunoglobulin, kunitz and NTR domain-containing protein 1 is a protein that is encoded by the WFIKKN1 gene. when found in humans.

Brain-specific serine protease 4 (BSSP-4), also known as serine protease 22 or tryptase epsilon, is an enzyme that in humans is encoded by the PRSS22 gene.

Ribosomal protein S6 kinase, 90kDa, polypeptide 6 is a protein in humans that is encoded by the RPS6KA6 gene.

Calpain 6 is a protein in humans that is encoded by the CAPN6 gene.

Calcium/calmodulin-dependent protein kinase ID is a protein in humans that is encoded by the CAMK1D gene on chromosome 10.

Protease, serine, 2 is a protein that in humans is encoded by the PRSS2 gene.

Protease, serine, 3 is a protein that in humans is encoded by the PRSS3 gene.

Rhomboid, veinlet-like 2 (Drosophila) is a protein that in humans is encoded by the RHBDL2 gene.

Rho associated coiled-coil containing protein kinase 2 is a protein that in humans is encoded by the ROCK2 gene.

Solute carrier family 38 member 5 is a protein that in humans is encoded by the SLC38A5 gene.

PGAM family member 5 (PGAM5), also known as mitochondrial Serine/threonine-protein phosphatase PGAM5 is related to phosphoglycerate mutase family. It, in humans, is encoded by the PGAM5 gene on chromosome 12.

Transmembrane serine protease 11F is a protein that in humans is encoded by the TMPRSS11F gene.

Transmembrane serine protease 7 is a protein that in humans is encoded by the TMPRSS7 gene.

Testis specific serine kinase 1B is a protein that in humans is encoded by the TSSK1B gene.

Serine protease 57 is a protein that in humans is encoded by the PRSS57 gene.

Serine/threonine kinase 11 interacting protein is a protein that in humans is encoded by the STK11IP gene.

References

1 2 3 ENSG00000285141 GRCh38: Ensembl release 89: ENSG00000184647, ENSG00000285141 - Ensembl, May 2017
1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000034623 - Ensembl, May 2017
↑ "Human PubMed Reference:".
↑ "Mouse PubMed Reference:".
↑ "Entrez Gene: Serine protease 55" . Retrieved 2018-04-24.

PRSS55

Contents

Function

Related Research Articles

References

Further reading