Panda German Shepherds

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Panda German Shepherds are German Shepherd dogs that exhibit a rare genetic mutation that causes white spotting in the traditionally non-white marked breed.

Contents

Genetics

The first ever recorded Panda mutation occurred spontaneously in a female dog, Lewcinka's Franka von Phenom, in 2000.

A study published by UCDavis in 2016 found that the Panda marking is the result of dominant mutation of the KIT gene, or the CD117 gene. [1] DNA tested conducted by the American Kennel Club proved her lineage to be, for a fact, a pure German Shepherd Dog.

Panda is a dominant gene. In its homozygous state, the mutation is considered embryonic lethal as no live dog has been observed with it. [2]

Controversy

Due to fact that any white markings is considered a fault for showing, [3] many German Shepherd fanciers assume that this color as a result of crossbreeding to Collies or similar breeds. Many traditional breeders also believe that this color is from inferior stock, and that many breeders of this coloration are going against the GSDCA Code of Ethics.

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Overo

Overo refers to several genetically unrelated pinto coloration patterns of white-over-dark body markings in horses, and is a term used by the American Paint Horse Association to classify a set of pinto patterns that are not tobiano. Overo is a Spanish word, originally meaning "like an egg". The most common usage refers to frame overo, but splashed white and sabino are also considered "overo". A horse with both tobiano and overo patterns is called tovero.

White horse

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Sabino horse Color pattern in horses

Sabino describes a distinct pattern of white spotting in horses. In general, Sabino patterning is visually recognized by roaning or irregular edges of white markings, belly spots, white extending past the eyes or onto the chin, white above the knees or hocks, and "splash" or "lacy" marks anywhere on the body. Some sabinos have patches of roan patterning on part of the body, especially the barrel and flanks. Some sabinos may have a dark leg or two, but many have four white legs. Sabino patterns may range from slightly bold face or leg white markings—as little as white on the chin or lower lip—to horses that are fully white.

Splashed white

Splashed white or splash is a horse coat color pattern in the "overo" group of spotting patterns that produces pink-skinned, white markings. Many splashed whites have very modest markings, while others have the distinctive "dipped in white paint" pattern. Blue eyes are a hallmark of the pattern, and splash may account for otherwise "solid" blue-eyed horses. Splashed white occurs in a variety of geographically divergent breeds, from Morgans in North America to Kathiawari horses in India. The splashed white pattern is also associated with congenital deafness, though most splashed whites have normal hearing. Splashed white can be caused by multiple variants across two different genes, for which genetic testing is available.

Dominant white Horse coat color and its genetics

Dominant white (W) is a group of genetically related coat color alleles on the KIT gene of the horse, best known for producing an all-white coat, but also able to produce various forms of white spotting, as well as bold white markings. Prior to the discovery of the W alllelic series, many of these patterns were described by the term sabino, which is still used by some breed registries.

Roan (horse) Horse coat color pattern characterized by an even mixture of colored and white hairs on the body

Roan is a horse coat color pattern characterized by an even mixture of colored and white hairs on the body, while the head and "points"—lower legs, mane, and tail—are mostly solid-colored. Horses with roan coats have white hairs evenly intermingled throughout any other color. The head, legs, mane, and tail have fewer scattered white hairs or none at all. The roan pattern is dominantly inherited, and is found in many horse breeds. While the specific mutation responsible for roan has not been exactly identified, a DNA test can determine zygosity for roan in several breeds. True roan is always present at birth, though it may be hard to see until after the foal coat sheds out. The coat may lighten or darken from winter to summer, but unlike the gray coat color, which also begins with intermixed white and colored hairs, roans do not become progressively lighter in color as they age. The silvering effect of mixed white and colored hairs can create coats that look bluish or pinkish.

Ann T. Bowling American geneticist (1943–2000)

Ann Trommershausen Bowling was an American scientist who was one of the world's leading geneticists in the study of horses, conducting research in the areas of molecular genetics and cytogenetics. She was a major figure in the development of testing to determine animal parentage, first with blood typing in the 1980s and then DNA testing in the 1990s. She later became known for her studies of hereditary diseases in horses and equine coat color genetics, as well as research on horse evolution and the development of horse breeds. She studied the population genetics of feral horses, did considerable work to help preserve the Przewalski's horse, and was one of the founding members of the international project to map the horse genome. She was an adjunct professor at the University of California, Davis (UCD), and at the time of her death in 2000 was the executive associate director of the Veterinary Genetics Laboratory (VGL) there. Her unexpected death on December 8, 2000, at age 57 was attributed to a massive stroke.

References

  1. UC DAVIS. "Origin of Panda: White Spotting Gene". UC Davis Veterinary Genetics Laboratory. USDAVIS. Retrieved 18 November 2016.
  2. "White Spotting in German Shepherds". UC Davis Veterinary Genetics Laboratory. Retrieved 18 November 2016.
  3. "German Shepherd Standard". GSDCA. Retrieved 18 November 2016.