Pankaj Sharma is a British professor of Clinical Neurology [1] at Royal Holloway College, University of London, and consultant neurologist at Imperial College London. He is director of the Institute of Cardiovascular Research at Royal Holloway (ICR2UL), [2] and formerly head of the Imperial College Cerebrovascular Research Unit (ICCRU) at Imperial College London. [3] His main interest is in identifying genes for stroke, particularly in those of South Asian heritage.
He was president of the British Fulbright Scholars Association and is currently Medical Advisor of the UK national young stroke victim charity Different Strokes, [4] co-founder and treasurer of the South Asian Health Foundation (1998). [5] He is a Fellow of the Medical Society of London, editor-in-chief of the Journal of the Royal Society of Medicine Cardiovascular Disease, [6] president of the London Cardiovascular Society (2009), [7] and an expert external advisor to the Parliamentary and Health Service Ombudsman.
Sharma studied medicine at London University from 1983 to 1988 and holds two doctorates, a PhD from Gonville and Caius College, University of Cambridge in 1998 and a Doctorate in Medicine from London University in 2003. In 1998 he was the recipient of a Fulbright Scholarship at Harvard Medical School and Massachusetts General Hospital. [8] He holds a diploma in the history of medicine from the Worshipful Society of Apothecaries. He was elected a Fellow of the Royal College of Physicians in 2007 and is a Royal College examiner. [8]
He is a researcher in the field of stroke and is particularly interested in its genetical basis. He has established a large international biobank of stroke from the UK, India and the Middle East with the aim of trying to better understand the causes of stroke in ethnic minorities, especially those of South Asian descent.
He is the author of some 100 original papers and is the co-editor of two books: Stroke Genetics (Springer 2017; 2nd edition) and Clinical Pharmacology (Elsevier 2018) which is now in its twelfth edition.
Sharma has been a commentator for news media including the BBC and CNN International on medical issues especially relating to stroke. He has been interviewed on the subject of brain disease in prominent individuals including Ariel Sharon, Michael Schumacher and Jules Bianchi.
Sharma received a British Heart Foundation Clinician Scientist award in 1997, and in 2010 he was one of the recipients of the Hind Rattan award.[ citation needed ]
In 2015, he was named the UK's top Asian doctor at the annual British Indian Awards. [9] [10]
He was born in Delhi, the son of Kewal Krishan Sharma (Indian Foreign diplomatic service who served under three prime ministers, Nehru, Shastri and Indira Gandhi) and Janak Sharma (Bank of England). Under his grandfather, Bihari Lal Sharma, the family was noted for holding the licence for Kodak prior to India's partition. He is chairman of the UK charity founded by his family, Lotus Partners Foundation. He lists his hobbies as debating, fencing [11] and playing polo and describes himself as 'generous, disciplined and maverick'. [12] Sharma lives in London with his doctor wife and two children, Aarti and Shyam.
Sharma has a neurology private practice [13] in Harley Street.
Angela Vincent is Emeritus professor at the University of Oxford and a Fellow of Somerville College, Oxford.
Cerebrovascular disease includes a variety of medical conditions that affect the blood vessels of the brain and the cerebral circulation. Arteries supplying oxygen and nutrients to the brain are often damaged or deformed in these disorders. The most common presentation of cerebrovascular disease is an ischemic stroke or mini-stroke and sometimes a hemorrhagic stroke. Hypertension is the most important contributing risk factor for stroke and cerebrovascular diseases as it can change the structure of blood vessels and result in atherosclerosis. Atherosclerosis narrows blood vessels in the brain, resulting in decreased cerebral perfusion. Other risk factors that contribute to stroke include smoking and diabetes. Narrowed cerebral arteries can lead to ischemic stroke, but continually elevated blood pressure can also cause tearing of vessels, leading to a hemorrhagic stroke.
Stroke is a medical condition in which poor blood flow to the brain causes cell death. There are two main types of stroke: ischemic, due to lack of blood flow, and hemorrhagic, due to bleeding. Both cause parts of the brain to stop functioning properly.
Sir Magdi Habib Yacoub, is an Egyptian retired professor of cardiothoracic surgery at Imperial College London, best known for his early work in repairing heart valves with surgeon Donald Ross, adapting the Ross procedure, where the diseased aortic valve is replaced with the person's own pulmonary valve, devising the arterial switch operation (ASO) in transposition of the great arteries, and establishing the heart transplantation centre at Harefield Hospital in 1980 with a heart transplant for Derrick Morris, who at the time of his death was Europe's longest-surviving heart transplant recipient. Yacoub subsequently performed the UK's first combined heart and lung transplant in 1983.
Sir Richard Peto is an English statistician and epidemiologist who is Professor of Medical Statistics and Epidemiology at the University of Oxford, England.
Kamran Abbasi is the editor-in-chief of the British Medical Journal (BMJ), a physician, visiting professor at the Department of Primary Care and Public Health, Imperial College, London, editor of the Journal of the Royal Society of Medicine(JRSM), journalist, cricket writer and broadcaster, who contributed to the expansion of international editions of the BMJ and has argued that medicine cannot exist in a political void.
Sir Michael Gideon Marmot is Professor of Epidemiology and Public Health at University College London. He is currently the Director of The UCL Institute of Health Equity. Marmot has led research groups on health inequalities for over thirty years, working for various international and governmental bodies. In 2023, he was elected to the American Philosophical Society.
Ara Warkes Darzi, Baron Darzi of Denham, is an Armenian-British surgeon, academic, and politician.
Trevor A. Sheldon is a British academic and University administrator who is a former Deputy Vice-Chancellor of the University of York and Dean of Hull York Medical School. He has held academic posts at the University of York, the University of Leeds, the University of Leicester and Kingston University.
Avijit Lahiri is a researcher in cardiology in the UK.
Sir Rory Edwards Collins FMedSci FRS is a British physician who is Professor of Medicine and Epidemiology at the Clinical Trial Service Unit within the University of Oxford, the head of the Nuffield Department of Population Health and a Fellow of Green Templeton College, Oxford. His work has been in the establishment of large-scale epidemiological studies of the causes, prevention and treatment of heart attacks, other vascular disease, and cancer, while also being closely involved in developing approaches to the combination of results from related studies ("meta-analyses"). Since September 2005, he has been the Principal Investigator and Chief Executive of the UK Biobank, a prospective study of 500,000 British people aged 40–69 at recruitment.
Louis R. Caplan is an American physician who is a senior member of the Division of Cerebrovascular Disease at Beth Israel Deaconess Medical Center, Boston. He is a Professor of Neurology at Harvard Medical School, Boston, and the founder of the Harvard Stroke Registry at Beth Israel Deaconess Medical Center. Caplan is the author or editor of 51 books and more than 700 articles in medical journals.
Andrew Nicolaides is a British-Greek Cypriot surgeon, and an expert in cardiovascular disease and stroke prevention.
Sir John Irving Bell is a Canadian-British immunologist and geneticist. From 2006 to 2011, he was President of the United Kingdom's Academy of Medical Sciences, and since 2002 he has held the Regius Chair of Medicine at the University of Oxford. He was since 2006 Chairman of the Office for Strategic Coordination of Health Research (OSCHR) but in 2020 became a normal member. Bell was selected to the Vaccine Taskforce sometime before 1 July 2020. Bell is also on the board of directors of the SOE quango Genomics England.
Hugh Christian Watkins is a British cardiologist. He is a Fellow of Merton College, Oxford, an associate editor of Circulation Research, and was Field Marshal Alexander Professor of Cardiovascular Medicine in the University of Oxford between 1996 and 2013.
Dame Parveen June Kumar is a British doctor who is currently Professor of Medicine and Education at Barts and The London School of Medicine and Dentistry. She worked in the NHS for over 40 years as a consultant gastroenterologist and physician at Barts and the London Hospitals and the Homerton University Hospital. She was the President of the British Medical Association in 2006, of the Royal Society of Medicine from 2010 to 2012, of the Medical Women's Federation from 2016 to 2018 and of the Royal Medical Benevolent Fund from 2013 to 2020. She was also Vice President of the Royal College of Physicians from 2003 to 2005. In addition, she was a founding non-executive director of the National Institute of Clinical Excellence, chaired the Medicines Commission UK until 2005, and also chaired the BUPA Foundation Charity for Research until 2013.
The Liverpool Neurological Infectious Diseases Course is an annual two-day course aimed at medical professionals and students with an interest in neurological infectious diseases. The course is organised by the Liverpool Brain Infections Group, a division of the Institute of Infection and Global Health at the University of Liverpool, in collaboration with the Walton Centre NHS Foundation Trust, Alder Hey Children’s NHS Trust, Royal Liverpool University Hospital, and Liverpool School of Tropical Medicine, and is chaired by the neurologist Tom Solomon. It takes place during May at the historic Liverpool Medical Institution, in Liverpool, UK. A variety of both national and international speakers contribute to a programme which covers clinical aspects of common central nervous system infections such as meningitis and encephalitis, as well as rarer neurological infections and talks on recent advances in related research. The course is accredited by the UK Royal College of Physicians, and attracts delegates from many countries worldwide.
Vladimir Hachinski is a Canadian clinical neuroscientist and researcher based at the Schulich School of Medicine and Dentistry at Western University. He is also a Senior Scientist at London's Robarts Research Institute. His research pertains in the greatest part to stroke and dementia, the interactions between them and their joint prevention. He and John W. Norris helped to establish the world's first successful stroke unit at Sunnybrook Hospital in Toronto, and, by extension, helped cement stroke units as the standard of care for stroke patients everywhere. He discovered that the control of the heart by the brain is asymmetric, the fight/flight (sympathetic) response being controlled by the right hemisphere and the rest and digest (parasympathetic) response being controlled by the left hemisphere and damage to one key component can lead to heart irregularities and sudden death. This discovery has added fundamental knowledge to how the brain controls the heart and blood pressure and lays the foundation for helping prevent sudden death.
Sir Patrick John Thompson Vallance is a British physician, scientist, and clinical pharmacologist who has worked in both academia and industry. He served as the Chief Scientific Adviser to the Government of the United Kingdom from 2018 to 2023.
Raad Shakir CBE is Professor of Neurology at Imperial College London and a Consultant Neurologist at Charing Cross Hospital.