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Male infertility refers to a sexually mature male's inability to impregnate a fertile female. In humans it accounts for 40–50% of infertility. It affects approximately 7% of all men. Male infertility is commonly due to deficiencies in the semen, and semen quality is used as a surrogate measure of male fecundity. More recently, advance sperm analyses that examine intracellular sperm components are being developed.
The cation channels of sperm also known as Catsper channels or CatSper, are ion channels that are related to the two-pore channels and distantly related to TRP channels. The four members of this family form voltage-gated Ca2+ channels that seem to be specific to sperm. As sperm encounter the more alkaline environment of the female reproductive tract, CatSper channels become activated by the altered ion concentration. These channels are required for proper fertilization. The study of these channels has been slow because they do not traffic to the cell membrane in many heterologous systems.
Ashok Agarwal is the Director of the Andrology Center, and also the Director of Research at the American Center for Reproductive Medicine at Cleveland Clinic, Cleveland, USA. He is Professor at the Cleveland Clinic Lerner College of Medicine of Case Western Reserve University, USA. Ashok is a Senior Staff in the Cleveland Clinic's Glickman Urological and Kidney Institute. He has published extensive translational research in human infertility and assisted reproduction.
JoGayle Dillon Howard (1951–2011) was an American zoologist and theriogenologist specializing in the captive breeding of endangered species such as pandas, clouded leopards, and black-footed ferrets.
Geraldine Lee Richmond is an American chemist and physical chemist who is serving as the Under Secretary of Energy for Science in the US Department of Energy. Richmond was confirmed to her DOE role by the United States Senate on November 5, 2021. Richmond is the Presidential Chair in Science and Professor of Chemistry at the University of Oregon (UO). She conducts fundamental research to understand the chemistry and physics of complex surfaces and interfaces. These understandings are most relevant to energy production, atmospheric chemistry and remediation of the environment. Throughout her career she has worked to increase the number and success of women scientists in the U.S. and in many developing countries in Africa, Asia and South America. Richmond has served as president of the American Association for the Advancement of Science, and she received the 2013 National Medal of Science.
Rosemary Gillespie is an evolutionary biologist and professor of Environmental Science, Policy & Management, Division of Insect Biology at the University of California, Berkeley. She was the President of the American Genetics Association in 2018 and was previously President of the International Biogeography Society 2013–2015. From 2011 to 2013 she had served at the president of the American Arachnological Society. As of 2020 she is the faculty director of the Essig Museum of Entomology and a Professor and Schlinger Chair in systematic entomology at the University of California, Berkeley. Gillespie is known for her work on the evolution of communities on hotspot archipelagoes.
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Minerva Cordero Braña is a Puerto Rican mathematician and a professor of mathematics at the University of Texas at Arlington. She is also the university's Senior Associate Dean for the College of Science, where she is responsible for the advancement of the research mission of the college. President Biden awarded her the Presidential Award for Excellence in Science, Mathematics, and Engineering Mentoring (PAESMEM) on February 8, 2022.
Erika Tatiana Camacho is a Mexican-born American mathematical biologist and professor of applied mathematics at Arizona State University. She is a 2014 Presidential Award for Excellence in Science, Mathematics, and Engineering Mentoring (PAESMEM) awardee. She was taught and mentored in high school by Jaime Escalante, who was the subject of the movie Stand and Deliver.
Wei Yan is a Chinese-American reproductive biologist, currently Professor of Medicine at David Geffen School of Medicine at UCLA and Senior Investigator at The Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical Center. He is also University Foundation Professor at University of Nevada, Reno, United States and an Elected Fellow of the American Association for the Advancement of Science. He is Director of National Center for Male Reproductive Epigenomics and served as the editor-in-chief of the journal Biology of Reproduction.
Robert John Aitken is a British reproductive biologist, widely known for identifying oxidative stress as a significant contribution to infertility and its actions on human sperm function. He also made substantial contributions to clinical practice translation in male reproductive health, notably the development of new contraceptive vaccine.
Margaret (Maggie) Werner-Washburne is a molecular biologist and Regents' Professor Emeritus of Biology. at the University of New Mexico. She was previously the president (2013–2015) of the Society for the Advancement of Chicanos/Hispanics and Native Americans in Science (SACNAS), which holds the largest broadly multidisciplinary and multicultural STEM diversity conference in the U.S. A pioneer in the genomics of the stationary phase of yeast, she is known for her innovative programs to attract and retain underrepresented minorities in STEM. Werner-Washburne has made great strides in the field of Genetics. She has done gene sequencing with organisms that are disease vectors, which allows a greater understanding of genetics in general.
Claudia Benitez-Nelson is a Latinx American oceanographer whose research focuses on marine geochemistry and biogeochemistry. A Carolina Distinguished Professor, she serves as the Senior Associate Dean for College Initiatives and Interdisciplinary Programs at the University of South Carolina’s College of Arts and Sciences.
Elba E. Serrano is a neuroscientist and biophysicist who holds a position as a Regent's Professor of Biology at New Mexico State University.
Therese Ann Markow is the Amylin Chair in Life Sciences at the University of California, San Diego. Her research involves the use of genetics and ecology to study the insects of the Sonoran Desert. She was awarded the Presidential Early Career Award for Scientists and Engineers in 2001 and the Genetics Society of America George Beadle Award in 2012. Her research received widespread attention for its alleged misuse of Native American genetic data.
Sarah Martins Da SilvaMRCOG is a British gynaecologist and researcher specialising in male infertility. Da Silva is a senior lecturer in reproductive medicine at the University of Dundee. She also works as an honorary consultant gynaecologist at the Ninewells Hospital in Dundee, specialising in fertility problems and assisted conception. She was named one of the BBC's "100 Women of 2019" for her contribution to fertility science.
Maria Elena Zavala is an American plant biologist. She was the first Mexican-American woman to earn a PhD in botany in the United States. She is currently a full professor of biology at the California State University-Northridge, studying plant development. She is a Fellow of the American Association for the Advancement of Science, the first Latina fellow of the American Society of Plant Biologists, the first Latina fellow of the American Society of Cell Biology, and an elected fellow of the Institute of Science. In 2000, she was awarded the Presidential Award for Excellence in Science, Mathematics, and Engineering Mentoring, which recognises individuals who have increased the participation of underrepresented minorities in their fields.
Claire Brindis, DrPH, is a Distinguished Emerita Professor of Pediatrics and Health Policy, Department of Pediatrics and Department of Obstetrics, Gynecology and Reproductive Health Sciences and Emerita Director of the Philip R. Lee Institute for Health Policy Studies at the University of California, San Francisco (UCSF). Her research considers women's, adolescent and child health, as well as adolescent pregnancy prevention strategies. She was elected a member of the Institute of Medicine in 2010.
References
- 1 2 Nowak, Romana A. (2018-11-01). "An interview with Dr Patricia A. Martin-DeLeon". Biology of Reproduction. 99 (5): 899–902. doi: 10.1093/biolre/ioy103 . ISSN 0006-3363. PMID 30561557.
- 1 2 3 "AlisonAwardDeLeon". www.bio.udel.edu. Retrieved 2020-08-02.
- ↑ "Patricia Martin-DeLeon". Icons. 2017-06-21. Retrieved 2020-08-02.
- ↑ "Patricia A. DeLeon, PhD". Careers in Andrology. Retrieved 2020-08-02.
- ↑ "Patricia DeLeon's Biography". The HistoryMakers. Retrieved 2020-08-02.
- ↑ contributor, Joey Davidson / (2017-01-13). "This UD researcher hopes to make in vitro fertilization much more affordable". Technical.ly Delaware. Retrieved 2020-08-02.
{{cite web}}:|last=has generic name (help) - ↑ "PAESMEM » Awardee Profile". paesmem.net. Retrieved 2020-08-02.
- ↑ American Society of Andrology (April 5, 2005). "ASA 30th Annual Meeting Program" (PDF). American Society of Andrology. Retrieved May 23, 2023.
{{cite web}}: CS1 maint: url-status (link) - ↑ "Patricia Martin-DeLeon: Scientist par Excellence! | Mona E-Connection". www.mona.uwi.edu. Retrieved 2020-08-02.
- ↑ "President Honors Outstanding Science, Math, Engineering Teachers and Mentors". whitehouse.gov. 2009-07-09. Retrieved 2020-08-02.
- ↑ "11th William G. Demas Lecture" . Retrieved 2020-08-02.
- ↑ "50 Most Outstanding Jamaican Women - Record". calameo.com. Retrieved 2020-08-02.
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