Schedl has made significant contributions to the field of the control of gene expression in developmental systems using the model system Drosophila melanogaster. On the genomic level, his lab has uncovered the mechanisms of chromatin regulation by the Polycomb and trithorax group genes. At the transcriptional and post-transcriptional level, he made discoveries in the regulation of alternative splicing of the sex determination gene, Sxl. At the level of translational control, he discovered the function of the orb and orb2 gene in early development.
As of 2006, Schedl has published 132 papers, mentored 28 graduate students, sponsored 25 postdoctoral fellows and collaborated with 79 scientists.
Schedl was born to Harold Schedl, a professor of chemistry at the University of Iowa, and Naomi Schedl, a professor of art. He has two brothers, Andrew Schedl and Timothy Schedl.
William McGinnis, Ph.D. is a molecular biologist and professor of biology at the University of California San Diego. At UC San Diego he has also served as the Chairman of the Department of Biology from July 1998 - June 1999, as Associate Dean of the Division of Natural Sciences from July 1, 1999 - June 2000, and as Interim Dean of the newly established Division of Biological Sciences from July 1, 2000 - February 1, 2001. Dr. McGinnis was appointed Dean of the Divisional Biological Sciences on July 1, 2013.
Tom Maniatis, is an American professor of molecular and cellular biology.
Roger David Kornberg is an American biochemist and professor of structural biology at Stanford University School of Medicine. Kornberg was awarded the Nobel Prize in Chemistry in 2006 for his studies of the process by which genetic information from DNA is copied to RNA, "the molecular basis of eukaryotic transcription."
Barbara J. Meyer is a biologist and genetist, noted for her pioneering research on lambda phage, a virus that infects bacteria; discovery of the master control gene involved in sex determination; and studies of gene regulation, particularly dosage compensation. Meyer’s work has revealed mechanisms of sex determination and dosage compensation -- that balance X-chromosome gene expression between the sexes in Caenorhabditis elegans that continue to serve as the foundation of diverse areas of study on chromosome structure and function today.
Timothy Schedl is a professor of genetics at Washington University in St. Louis.
Franklin Gerardus "Frank" Grosveld, FRS is a Dutch molecular biologist whose research interests are in the regulation of transcription during development with a particular emphasis on mammalian erythroid differentiation. He is a professor and Head of the Department of Cell Biology at the Erasmus MC, Rotterdam.
Michael B. Elowitz is a biologist and professor of Biology, Bioengineering, and Applied Physics at the California Institute of Technology, and investigator at the Howard Hughes Medical Institute. In 2007 he was the recipient of the Genius grant, better known as the MacArthur Fellows Program for the design of a synthetic gene regulatory network, the Repressilator, which helped initiate the field of synthetic biology. In addition, he showed, for the first time, how inherently random effects, or 'noise', in gene expression could be detected and quantified in living cells, leading to a growing recognition of the many roles that noise plays in living cells. His work in Synthetic Biology and Noise represent two foundations of the field of Systems Biology.
Thomas Christian Südhof, ForMemRS, is a German-American biochemist known for his study of synaptic transmission. Currently, he is a professor in the School of Medicine in the Department of Molecular and Cellular Physiology, and by courtesy in Neurology, and in Psychiatry and Behavioral Sciences at Stanford University.
Uri Alon is a Professor and Systems Biologist at the Weizmann Institute of Science. His highly cited research investigates gene expression, network motifs and the design principles of biological networks in Escherichia coli and other organisms using both computational biology and traditional experimental wet laboratory techniques.
Keith R. Yamamoto is Vice Chancellor for Research, Executive Vice Dean of the School of Medicine, and Professor of Cellular and Molecular Pharmacology at the University of California, San Francisco, UCSF. He is known for his Molecular Biology and Biochemistry research on nuclear receptors and his involvement in science policy. He identified the genomic sequences to which the glucocorticoid receptor (GR) binds in order to control gene transcription termed "glucocorticoid response elements". He is also a leader in science policy, serving as Chairman of the Board on Life Sciences at the National Academy of Sciences, as well as numerous government and public advisory boards, including the NIH Center for Scientific Review Advisory Council.
Michael Levine is an American developmental and cell biologist at Princeton University, where he is the Director of the Lewis-Sigler Institute for Integrative Genomics and a Professor of Molecular Biology.
Michael Morris Rosbash is an American geneticist and chronobiologist. Rosbash is a professor and researcher at Brandeis University and investigator at the Howard Hughes Medical Institute. Rosbash's research group cloned the Drosophila period gene in 1984 and proposed the Transcription Translation Negative Feedback Loop for circadian clocks in 1990. In 1998, they discovered the cycle gene, clock gene, and cryptochrome photoreceptor in Drosophila through the use of forward genetics, by first identifying the phenotype of a mutant and then determining the genetics behind the mutation. Rosbash was elected to the National Academy of Sciences in 2003. Along with Michael W. Young and Jeffrey C. Hall, he was awarded the 2017 Nobel Prize in Physiology or Medicine "for their discoveries of molecular mechanisms controlling the circadian rhythm".
Jeffrey Connor Hall is an American geneticist and chronobiologist. Hall is Professor Emeritus of Biology at Brandeis University and currently resides in Cambridge, Maine.
Professor Judith Kimble is a Henry Vilas Professor of Biochemistry, Molecular Biology, Medical Genetics and Cell and Regenerative Biology at the University of Wisconsin–Madison and Investigator with the Howard Hughes Medical Institute (HHMI). Professor Kimble’s research focuses on the molecular regulation of animal development.
Usha Vijayraghavan is on the faculty of the Department of Microbiology and Cell Biology, at the Indian Institute of Science (IISc), Bangalore. Her major research interests are Molecular Genetics, Plant Development.
Steve A. Kay is a British-born chronobiologist who mainly works in the United States. Dr. Kay has pioneered methods to monitor daily gene expression in real time and characterized circadian gene expression in plants, flies and mammals. In 2014, Steve Kay celebrated 25 years of successful chronobiology research at the Kaylab 25 Symposium, joined by over one hundred researchers with whom he had collaborated with or mentored. Dr. Kay, a member of the National Academy of Sciences, U.S.A., briefly served as president of The Scripps Research Institute. and is currently a professor at the University of Southern California.
Paul Hardin is a prominent scientist in the field of chronobiology and a pioneering researcher in the understanding of circadian clocks in flies and mammals. Hardin currently serves as a distinguished professor in the biology department at Texas A&M University. He is best known for his discovery of circadian oscillations in the mRNA of the clock gene Period (per), the importance of the E-Box in per activation, the interlocked feedback loops that control rhythms in activator gene transcription, and the circadian regulation of olfaction in Drosophila melanogaster. Born in a suburb of Chicago, Matteson, Illinois, Hardin currently resides in College Station, Texas, with his wife and three children.
Michael Karin is an Israeli-American Distinguished Professor of Pharmacology, Ben and Wanda Hildyard Chair for Mitochondrial and Metabolic Diseases, American Cancer Society Research Professor at the University of California, San Diego.
Alexander Stark is a biochemist and computational biologist working on the regulation of gene expression in development. He is a senior scientist at the Research Institute of Molecular Pathology (IMP) at the Vienna Biocenter and adjunct professor of the Medical University of Vienna.
Carla Beth Green is an American neurobiologist and chronobiologist. She is a professor in the Department of Neuroscience and a Distinguished Scholar in Neuroscience at the University of Texas Southwestern Medical Center. She is the former president of the Society for Research on Biological Rhythms (SRBR), as well as a satellite member of the International Institute for Integrative Sleep Medicine at the University of Tsukuba in Japan.
This page is based on this Wikipedia article Text is available under the CC BY-SA 4.0 license; additional terms may apply. Images, videos and audio are available under their respective licenses.
