Polly Roy

Last updated

Polly Roy

OBE
Born
Calcutta, India
Scientific career
InstitutionsLondon School of Hygiene and Tropical Medicine

Polly Roy OBE is a professor and Chair of Virology at The London School of Hygiene and Tropical Medicine. [1] [2] She attended a number of schools which included Columbia University Medical School, Rutgers University, University of Alabama, and University of Oxford. In 2001 she became a part of The London School of Hygiene and Tropical Medicine and, along with being the chair of Virology, is also the co-organiser of the medical microbiology course. The virus that she has dedicated most of her career to is Bluetongue disease that affects sheep and cattle. She became interested in this virus after attending a symposium and was intrigued by the fact that not much was known about the virus that was causing such a nasty and sometimes fatal disease.

Contents

Education

Roy went to Presidency College in Calcutta, India, where she was born. Thereafter, she received a scholarship to study at New York University where she received her PhD in Molecular Virology. Whilst studying biological sciences she met biologist Sol Spiegelman. Roy then spent three years in a post-doctoral position in RNA Virology at Waksman Institute of Microbiology at Rutgers University. After her post-doctoral work, she went to the University of Alabama at Birmingham to begin her own RNA research group. She became a professor at University of Alabama at Birmingham in 1987. Roy then received the Fogarty Fellowship at the University of Oxford in 1997 where she established a second virology lab. In 2001 Roy moved to The Department of Pathogen Molecular Biology at the London School of Hygiene and Tropical Medicine [3] as a Virology professor where she leads a research groups.

Research

Throughout her career, Roy has improved understanding on basic molecular, and structural biology, replication and the transmission of a variety viruses.

Her research has led to advances in the development of improved diagnostic assays, more efficacious virus-like protein (VLP) vaccines, vaccines for Bluetongue and African Horse sickness virus (AHSV) and the possibility of other therapeutics relating to these diseases. [4]

Roy's research [5] has been published in multiple highly acclaimed journals [6] alongside contributing to several published books as a guest writer/editor.

Roy's current research includes gaining a clearer understanding around the blue tongue virus at a molecular level, the potential for developing vaccines for Bluetongue virus and the African Horse sickness virus, RNA-RNA interactions and packaging, cell entry and transcription activation of non-enveloped dsRNA viruses and defining the cis and trans acting factors in the assembly of the Bluetongue virus. [4]

Research interests

Contributions to our understanding of Bluetongue Virus

Honours and awards

Related Research Articles

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Bluetongue disease is a noncontagious, insect-borne, viral disease of ruminants, mainly sheep and less frequently cattle, yaks, goats, buffalo, deer, dromedaries, and antelope. It is caused by Bluetongue virus (BTV). The virus is transmitted by the midges Culicoides imicola, Culicoides variipennis, and other culicoids.

<span class="mw-page-title-main">Poliovirus</span> Enterovirus

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<i>Semliki Forest virus</i> Species of virus

The Semliki Forest virus is an alphavirus found in central, eastern, and southern Africa. It was first isolated from mosquitoes in the Semliki Forest, Uganda by the Uganda Virus Research Institute in 1942 and described by Smithburn and Haddow. It is known to cause disease in animals and humans.

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<span class="mw-page-title-main">Virus</span> Infectious agent that replicates in cells

A virus is a submicroscopic infectious agent that replicates only inside the living cells of an organism. Viruses infect all life forms, from animals and plants to microorganisms, including bacteria and archaea. Viruses are found in almost every ecosystem on Earth and are the most numerous type of biological entity. Since Dmitri Ivanovsky's 1892 article describing a non-bacterial pathogen infecting tobacco plants and the discovery of the tobacco mosaic virus by Martinus Beijerinck in 1898, more than 11,000 of the millions of virus species have been described in detail. The study of viruses is known as virology, a subspeciality of microbiology.

Anthony (Tony) Charles Minson, PhD, FMedSci is a British virologist known for his work on the biology of herpesviruses, and a university administrator. He was the Senior Pro-Vice-Chancellor of the University of Cambridge from 2003 to 2009. He is an emeritus professor of virology at the university's Department of Pathology and an emeritus fellow of Wolfson College.

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References

  1. "Academic experts profile: Polly Roy". The Guardian . 1 May 2007.
  2. "Polly Roy". LSHTM. Retrieved 6 December 2019.
  3. Crace, John (May 2007). "Interview". The Guardian. Guardian News and Media Limited. Retrieved 4 May 2015.
  4. 1 2 "Polly Roy". LSHTM. Retrieved 2 October 2019.
  5. "LSHTM Research Online". researchonline.lshtm.ac.uk. Retrieved 6 December 2019.
  6. Rao, Zihe; Belyaev, Alexander S.; Fry, Elizabeth; Roy, Polly; Jones, Ian M.; Stuart, David I. (December 1995). "Crystal structure of SIV matrix antigen and implications for virus assembly". Nature. 378 (6558): 743–747. Bibcode:1995Natur.378..743R. doi:10.1038/378743a0. ISSN   1476-4687. PMID   7501025. S2CID   4250591.
  7. "Prof Polly Roy - women leaders insight series". LSHTM. Retrieved 6 December 2019.
  8. LSHTM (20 March 2018), Polly Roy - How a virus works: a journey , retrieved 6 December 2019
  9. "Professor Polly Roy". bbsrc.ukri.org. Retrieved 6 December 2019.
  10. "No. 60895". The London Gazette (Supplement). 14 June 2014. p. b14.
  11. "Polly Roy". London School of Hygiene and Tropical Medicine. Retrieved 4 May 2015.
  12. "Wellcome Trust award for Polly Roy". Opinion. 7 December 2012. Retrieved 6 December 2019.
  13. "Polly Roy awarded gold medal for science". LSHTM. Retrieved 6 December 2019.