The Portland Press Excellence in Science Award was an annual award instituted in 1964 to recognize notable research in any branch of biochemistry undertaken in the UK or Republic of Ireland. It was initially called the CIBA Medal and Prize, then the Novartis Medal and Prize. The prize consists of a medal and a £3000 cash award. The winner is invited to present a lecture at a Society conference and submit an article to one of the Society's publications. [1] Notable recipients include the Nobel laureates John E. Walker, Paul Nurse, Sydney Brenner, César Milstein, Peter D. Mitchell, Rodney Porter, and John Cornforth.
The Novartis Medal and Prize was last presented in 2019 and will be replaced from 2021 by the Portland Press Excellence in Science Award. Portland Press is the publishing arm of the Biochemical Society. [2]
Source: Biochemical Society
Source: [1]
Sir Hans Adolf Krebs, FRS was a German-born British biologist, physician and biochemist. He was a pioneer scientist in the study of cellular respiration, a biochemical process in living cells that extracts energy from food and oxygen and makes it available to drive the processes of life. He is best known for his discoveries of two important sequences of chemical reactions that take place in the cells of humans and many other organisms, namely the citric acid cycle and the urea cycle. The former, often eponymously known as the "Krebs cycle", is the key sequence of metabolic reactions that provides energy in the cells of humans and other oxygen-respiring organisms; and its discovery earned Krebs a Nobel Prize in Physiology or Medicine in 1953. With Hans Kornberg, he also discovered the glyoxylate cycle, which is a slight variation of the citric acid cycle found in plants, bacteria, protists, and fungi.
Sir Edward Penley Abraham, was an English biochemist instrumental in the development of the first antibiotics penicillin and cephalosporin.
Dolichol refers to any of a group of long-chain mostly unsaturated organic compounds that are made up of varying numbers of isoprene units terminating in an α-saturated isoprenoid group, containing an alcohol functional group.
Sir Arthur Harden, FRS was a British biochemist. He shared the Nobel Prize in Chemistry in 1929 with Hans Karl August Simon von Euler-Chelpin for their investigations into the fermentation of sugar and fermentative enzymes. He was a founding member of the Biochemical Society and editor of its journal for 25 years.
David Keilin FRS was a Jewish scientist focusing mainly on entomology.
Sir Michael John Berridge was a British physiologist and biochemist.
Jennifer Moyle was a British biochemist who helped discover the chemiosmotic mechanism of ATP synthesis.
The halloween genes are a set of genes identified in Drosophila melanogaster that influence embryonic development. All of the genes code for cytochrome P450 enzymes in the ecdysteroidogenic pathway (biosynthesis of ecdysone from cholesterol). Ecdysteroids such as 20-hydroxyecdysone and ecdysone influence many of the morphological, physiological, biochemical changes that occur during molting in insects.
The Colworth Medal is awarded annually by the Biochemical Society to an outstanding research biochemist under the age of 35 and working mainly in the United Kingdom. The award is one of the most prestigious recognitions for young scientists in the UK, and was established by Tony James FRS at Unilever Research and Henry Arnstein of the Biochemical Society and takes its name from a Unilever research laboratory near Bedford in the UK, Colworth House.
Paul György (April 7, 1893 – March 1, 1976) was a Hungarian-born American biochemist, nutritionist, and pediatrician best known for his discovery of three B vitamins: riboflavin, B6, and biotin. Gyorgy was also well known for his research into the protective factors of human breast milk, particularly for his discoveries of Lactobacillus bifidus growth factor activity in human milk and its anti-staphylococcal properties. He was a recipient of the National Medal of Science in 1975 from President Gerald Ford.
Stefan Schuster is a German biophysicist. He is professor for bioinformatics at the University of Jena.
Alan Hall FRS was a British cell biologist and a biology professor at the Sloan-Kettering Institute, where he was chair of the Cell Biology program. Hall was elected a Fellow of the Royal Society in 1999.
Pseudoenzymes are variants of enzymes that are catalytically-deficient, meaning that they perform little or no enzyme catalysis. They are believed to be represented in all major enzyme families in the kingdoms of life, where they have important signaling and metabolic functions, many of which are only now coming to light. Pseudoenzymes are becoming increasingly important to analyse, especially as the bioinformatic analysis of genomes reveals their ubiquity. Their important regulatory and sometimes disease-associated functions in metabolic and signalling pathways are also shedding new light on the non-catalytic functions of active enzymes, of moonlighting proteins, the re-purposing of proteins in distinct cellular roles. They are also suggesting new ways to target and interpret cellular signalling mechanisms using small molecules and drugs. The most intensively analyzed, and certainly the best understood pseudoenzymes in terms of cellular signalling functions are probably the pseudokinases, the pseudoproteases and the pseudophosphatases. Recently, the pseudo-deubiquitylases have also begun to gain prominence.
Sibyl Taite Widdows (1876–1960) was a British Scientist and member of the Chemistry department at the London School of Medicine for Women for 40 years.
Matthew Johnson is a Reader in Biochemistry at the University of Sheffield, England. He was the 2018 recipient of the Biochemical Society’s Colworth Medal.
Kiyoshi Nagai was a Japanese structural biologist at the MRC Laboratory of Molecular Biology Cambridge, UK. He was known for his work on the mechanism of RNA splicing and structures of the spliceosome.
Paula Jane Booth is an English chemist who holds the Daniell Chair of Chemistry at King's College London and is Head of Department. Booth was awarded a Philip Leverhulme Prize in 2003, a Royal Society Wolfson Research Merit Award in 2008 and an ERC Advanced grant in 2012 for her novel work on investigating the mechanisms of biological self-assembly.
Carbon Catabolite Repression—Negative On TATA-less, or CCR4-Not, is a multiprotein complex that functions in gene expression. The complex has multiple enzymatic activities as both a poly(A) 3′-5′ exonuclease and a ubiquitin ligase. The complex is present both in the nucleus where it regulates transcription and in the cytoplasm where it associates with translating ribosomes and RNA processing bodies.
Julia Anne Horsfield is a New Zealand biochemist and developmental geneticist. She is professor of pathology at the University of Otago and director of Genetics Otago and the Otago Zebrafish Facility.
Nicki Packer FRSC is a Distinguished Professor of Glycoproteomics in the School of Natural Sciences at Macquarie University and Principal Research Leader at Griffith University's Institute for Glycomics. Packer is a Fellow of the Royal Society of Chemistry and in 2021 received the Distinguished Achievement in Proteomic Sciences Award from the Human Proteome Organization. Her research focuses on biological functional of glycoproteins by linking glycomics with proteomics and bioinformatics.
The Ciba Medal Lecture 'Inositol lipids and phosphates in cell regulation' was delivered by Bob Michell at the December [1989] meeting at St. Bartholomew’s Hospital Medical College...