Pseudomonas virus 42 | |
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Virus classification ![]() | |
(unranked): | Virus |
Realm: | Duplodnaviria |
Kingdom: | Heunggongvirae |
Phylum: | Uroviricota |
Class: | Caudoviricetes |
Order: | Caudovirales |
Family: | Myoviridae |
Genus: | incertae sedis |
Species: | Pseudomonas virus 42 |
Synonyms | |
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Pseudomonas virus 42, formerly Pseudomonas phage 42, is a bacteriophage known to infect Pseudomonas bacteria. [1] [2]
A bacteriophage, also known informally as a phage, is a duplodnaviria virus that infects and replicates within bacteria and archaea. The term was derived from "bacteria" and the Greek φαγεῖν, meaning "to devour". Bacteriophages are composed of proteins that encapsulate a DNA or RNA genome, and may have structures that are either simple or elaborate. Their genomes may encode as few as four genes and as many as hundreds of genes. Phages replicate within the bacterium following the injection of their genome into its cytoplasm.
Phage therapy, viral phage therapy, or phagotherapy is the therapeutic use of bacteriophages for the treatment of pathogenic bacterial infections. This therapeutic approach emerged at the beginning of the 20th century but was progressively replaced by the use of antibiotics in most parts of the world after the second world war. Bacteriophages, known as phages, are a form of virus that attach to bacterial cells and inject their genome into the cell. The bacteria's production of the viral genome interferes with its ability to function, halting the bacterial infection. The bacterial cell causing the infection is unable to reproduce, and instead produces additional phages. Phages are very selective in the strains of bacteria they are effective against.
Escherichia virus T4 is a species of bacteriophages that infect Escherichia coli bacteria. It is a double-stranded DNA virus in the subfamily Tevenvirinae from the family Myoviridae. T4 is capable of undergoing only a lytic lifecycle and not the lysogenic lifecycle. The species was formerly named T-even bacteriophage, a name which also encompasses, among other strains, Enterobacteria phage T2, Enterobacteria phage T4 and Enterobacteria phage T6.
Podoviridae is a family of bacteriophage in the order Caudovirales often associated with T-7 like phages. There are 130 species in this family, assigned to 3 subfamilies and 52 genera. This family is characterized by having very short, noncontractile tails. Podoviradae are largely understudied and most new isolates are of the phicbkviruses genus, a group of giant viruses that appear to be Caulobacter specific.
Filamentous bacteriophage is a family of viruses (Inoviridae) that infect bacteria. The phages are named for their filamentous shape, a worm-like chain, about 6 nm in diameter and about 1000-2000 nm long. The coat of the virion comprises five types of viral protein, which are located during phage assembly in the inner membrane of the host bacteria, and are added to the nascent virion as it extrudes through the membrane. The simplicity of this family makes it an attractive model system to study fundamental aspects of molecular biology, and it has also proven useful as a tool in immunology and nanotechnology.
Cystovirus is a genus of double-stranded RNA viruses which infects bacteria. It is the only genus in the family Cystoviridae. The name of the group cysto derives from Greek kystis which means bladder or sack. There are seven species in this genus.
Fiersviridae is a family of positive-strand RNA viruses which infect prokaryotes. Bacteria serve as the natural host. They are small viruses with linear, positive-sense, single-stranded RNA genomes that encode four proteins. All phages of this family require bacterial pili to attach to and infect cells. The family has 185 genera, most discovered by metagenomics. In 2020, the family was renamed from Leviviridae to its current name.
Φ6 is the best-studied bacteriophage of the virus family Cystoviridae. It infects Pseudomonas bacteria. It has a three-part, segmented, double-stranded RNA genome, totalling ~13.5 kb in length. Φ6 and its relatives have a lipid membrane around their nucleocapsid, a rare trait among bacteriophages. It is a lytic phage, though under certain circumstances has been observed to display a delay in lysis which may be described as a "carrier state".
Tectiviridae is a family of viruses with 10 species in five genera. Bacteria serve as natural hosts. Tectiviruses have no head-tail structure, but are capable of producing tail-like tubes of ~ 60×10 nm upon adsorption or after chloroform treatment. The name is derived from Latin tectus.
Corticovirus is a genus of viruses in the family Corticoviridae. Corticoviruses are bacteriophages; that is, their natural hosts are bacteria. The genus contains two species. The name is derived from Latin cortex, corticis. However, prophages closely related to PM2 are abundant in the genomes of aquatic bacteria, suggesting that the ecological importance of corticoviruses might be underestimated. Bacteriophage PM2 was first described in 1968 after isolation from seawater sampled from the coast of Chile.
Outer membrane transport proteins (OMPP1/FadL/TodX) family includes several proteins that are involved in toluene catabolism and degradation of aromatic hydrocarbons. This family also includes protein FadL involved in translocation of long-chain fatty acids across the outer membrane. It is also a receptor for the bacteriophage T2.
Autographiviridae is a family of viruses in the order Caudovirales. Bacteria serve as natural hosts. There are 373 species in this family, assigned to 9 subfamilies and 133 genera.
Phikmvvirus is a genus of viruses that infect bacteria. There are currently 16 species in this genus including the type species Pseudomonas virus phiKMV. Bacteriophage phiKMV and its relatives are known to be highly virulent phages, producing large clear plaques on a susceptible host. The only reported exception is phage LKA1, which yields small plaques surrounded by a halo. While all other P. aeruginosa-specific phikmvviruses use the Type IV pili as primary receptor, LKA1 particles attach to the bacterial lipopolysaccharide layer.
Bruynoghevirus is a genus of viruses in the order Caudovirales, in the family Podoviridae. Bacteria serve as natural hosts. There are seven species in this genus.
Rauchvirus is a genus of viruses in the order Caudovirales, in the family Podoviridae. Bacteria serve as natural hosts. The genus contains only one species: Bordetella virus BPP1.
Enquatrovirus is a genus of bacteriophages in the order Caudovirales, in the family Podoviridae. Bacteria serve as natural hosts. There is currently only one species in this genus: the type species Escherichia virus N4.
Pseudomonas virus phiCTX is a virus of the family Myoviridae, genus Citexvirus.
Vibrio virus nt1 is a bacteriophage known to infect Vibrio bacteria. It infects Vibrio natriegens and was originally isolated from a coastal marsh, a frequent habitat of V. natriegens.
Hukuchivirus is a genus of double-stranded DNA viruses that infect thermophilic bacteria. The genus was previously named Gammasphaerolipovirus.
Pseudomonas virus gh1 is a bacteriophage capable of infecting susceptible strains of Pseudomonas putida. It is a member of family Podoviridae, subfamily Autographivirinae. It was first isolated in 1966 from a sample taken from the aeration tank at a sewage plant in East Lansing, Michigan.