RSPH14

RSPH14
Identifiers
Aliases	RSPH14 , RTDR1, radial spoke head 14 homolog
External IDs	MGI: 1918486 HomoloGene: 49382 GeneCards: RSPH14
Gene location (Human)
Chr.	Chromosome 22 (human) [1]
End	23,145,021 bp [1]
Gene location (Mouse)
Chr.	Chromosome 10 (mouse) [2]
End	75,032,586 bp [2]
Gene ontology
Molecular function	• protein binding ; • molecular function ;
Cellular component	• cellular component ;
Biological process	• biological process ;
	Sources:Amigo / QuickGO
Orthologs
	27156
	71236
	ENSG00000100218
	ENSMUSG00000009070
	Q9UHP6
	Q9D3W1
	NM_014433
	NM_001163533 ; NM_001163534 ; NM_001163535 ; NM_027730
	NP_055248
	NP_001157005 ; NP_001157006 ; NP_001157007 ; NP_082006
	Wikidata
View/Edit Human	View/Edit Mouse

Last updated May 04, 2019

Radial spoke head 14 homolog is a protein that in humans is encoded by the RSPH14 gene. ^[5]

Protein biological molecule consisting of chains of amino acid residues

Proteins are large biomolecules, or macromolecules, consisting of one or more long chains of amino acid residues. Proteins perform a vast array of functions within organisms, including catalysing metabolic reactions, DNA replication, responding to stimuli, providing structure to cells and organisms, and transporting molecules from one location to another. Proteins differ from one another primarily in their sequence of amino acids, which is dictated by the nucleotide sequence of their genes, and which usually results in protein folding into a specific three-dimensional structure that determines its activity.

In biology, a gene is a sequence of nucleotides in DNA or RNA that codes for a molecule that has a function. During gene expression, the DNA is first copied into RNA. The RNA can be directly functional or be the intermediate template for a protein that performs a function. The transmission of genes to an organism's offspring is the basis of the inheritance of phenotypic trait. These genes make up different DNA sequences called genotypes. Genotypes along with environmental and developmental factors determine what the phenotypes will be. Most biological traits are under the influence of polygenes as well as gene–environment interactions. Some genetic traits are instantly visible, such as eye color or number of limbs, and some are not, such as blood type, risk for specific diseases, or the thousands of basic biochemical processes that constitute life.

Function

This gene encodes a protein with no known function but with slight similarity to a yeast vacuolar protein. The gene is located in a region deleted in pediatric rhabdoid tumors of the brain, kidney and soft tissues, but mutations in this gene have not been associated with the disease.

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