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Rtf1, Paf1/RNA polymerase II complex component, homolog (S. cerevisiae) is a protein that in humans is encoded by the RTF1 gene. [1]
This locus may represent a gene involved in regulation of transcription elongation and chromatin remodeling, based on studies of similar proteins in other organisms. The encoded protein may bind single-stranded DNA. [1]
Exonucleases are enzymes that work by cleaving nucleotides one at a time from the end (exo) of a polynucleotide chain. A hydrolyzing reaction that breaks phosphodiester bonds at either the 3′ or the 5′ end occurs. Its close relative is the endonuclease, which cleaves phosphodiester bonds in the middle (endo) of a polynucleotide chain. Eukaryotes and prokaryotes have three types of exonucleases involved in the normal turnover of mRNA: 5′ to 3′ exonuclease (Xrn1), which is a dependent decapping protein; 3′ to 5′ exonuclease, an independent protein; and poly(A)-specific 3′ to 5′ exonuclease.
DNA-directed RNA polymerases I, II, and III subunit RPABC3 is a protein that in humans is encoded by the POLR2H gene.
DNA-directed RNA polymerase II subunit RPB4 is an enzyme that in humans is encoded by the POLR2D gene.
Transcription elongation factor SPT5 is a protein that in humans is encoded by the SUPT5H gene.
Cell division cycle 73, Paf1/RNA polymerase II complex component, homolog , also known as CDC73 and parafibromin, is a protein which in humans is encoded by the CDC73 gene.
Regulator of nonsense transcripts 1 is a protein that in humans is encoded by the UPF1 gene.
Mediator of RNA polymerase II transcription subunit 14 is an enzyme that in humans is encoded by the MED14 gene.
Transcription factor IIIB 90 kDa subunit is a protein that in humans is encoded by the BRF1 gene.
Transcription elongation factor SPT4 is a protein that in humans is encoded by the SUPT4H1 gene.
DNA-directed RNA polymerase III subunit RPC9 is an enzyme that in humans is encoded by the CRCP gene.
Cleavage and polyadenylation specificity factor subunit 3 is a protein that in humans is encoded by the CPSF3 gene.
Cleavage and polyadenylation specificity factor subunit 4 is a protein that in humans is encoded by the CPSF4 gene.
DNA-directed RNA polymerase III subunit RPC6 is an enzyme that in humans is encoded by the POLR3F gene.
Repressor of RNA polymerase III transcription MAF1 homolog is a protein that in humans is encoded by the MAF1 gene.
Zinc finger protein 143 is a protein that in humans is encoded by the ZNF143 gene.
DNA-directed RNA polymerase III subunit RPC3 is an enzyme that in humans is encoded by the POLR3C gene.
DNA-directed RNA polymerase III subunit RPC4 is an enzyme that in humans is encoded by the POLR3D gene.
RNA polymerase-associated protein LEO1 is an enzyme that in humans is encoded by the LEO1 gene.
DNA-directed RNA polymerase III subunit RPC5 is an enzyme that in humans is encoded by the POLR3E gene.
RNA polymerase-associated protein CTR9 homolog is an enzyme that in humans is encoded by the CTR9 gene.