Recombinetics is a St. Paul, Minnesota-based bio-engineering company. [1] The company was founded in 2008, and has since raised $31 million from private investors. Mark Platt is the CEO. [2]
In November 2024, Recombinetics filed for Chapter 11 bankruptcy protection. The company has plans to be acquired by Trans Ova Genetics for $4.1 million. [3]
It is known for developing genetically engineered hornless cattle, and is working on growing human organs and tissues in pigs. [4] While it created a cow that does not grow horns, during the creation process it also added genes from bacteria that could produce antibiotic resistance. [5] This occurred despite the CEO claiming that they had proof there were no other effects than the horns not being present. [5] Due to the bacterial DNA, it is unlikely that the animals will get FDA approval, and a number of them have been killed and the bodies burned. [5]
Cloning is the process of producing individual organisms with identical genomes, either by natural or artificial means. In nature, some organisms produce clones through asexual reproduction; this reproduction of an organism by itself without a mate is known as parthenogenesis. In the field of biotechnology, cloning is the process of creating cloned organisms of cells and of DNA fragments.
A genetically modified organism (GMO) is any organism whose genetic material has been altered using genetic engineering techniques. The exact definition of a genetically modified organism and what constitutes genetic engineering varies, with the most common being an organism altered in a way that "does not occur naturally by mating and/or natural recombination". A wide variety of organisms have been genetically modified (GM), including animals, plants, and microorganisms.
Genetic engineering, also called genetic modification or genetic manipulation, is the modification and manipulation of an organism's genes using technology. It is a set of technologies used to change the genetic makeup of cells, including the transfer of genes within and across species boundaries to produce improved or novel organisms.
Revlon, Inc. is an American multinational company dealing in cosmetics, skin care, perfume, and personal care. The headquarters of Revlon was established in New York City on March 1, 1932, where it remains. Revlon was founded by brothers Charles and Joseph Revson, and chemist Charles Lachman. Revlon products are sold in 150 countries and the company has many global locations including Mexico City, London, Paris, Hong Kong, Indonesia, Sydney, Singapore, and Tokyo.
Xenotransplantation, or heterologous transplant, is the transplantation of living cells, tissues or organs from one species to another. Such cells, tissues or organs are called xenografts or xenotransplants. It is contrasted with allotransplantation, syngeneic transplantation or isotransplantation and autotransplantation. Xenotransplantation is an artificial method of creating an animal-human chimera, that is, a human with a subset of animal cells. In contrast, an individual where each cell contains genetic material from a human and an animal is called a human–animal hybrid.
GNC Holdings, LLC is an American multinational retail and nutritional manufacturing company based in Pittsburgh, Pennsylvania. It specializes in health and nutrition related products, including vitamins, supplements, minerals, herbs, sports nutrition, diet, and energy products. It is a wholly owned subsidiary of Harbin Pharmaceutical Group, a Chinese state-owned pharmaceutical manufacturer.
Ancestry.com LLC is an American genealogy company based in Lehi, Utah. The largest for-profit genealogy company in the world, it operates a network of genealogical, historical records, and related genetic genealogy websites. It is owned by The Blackstone Group, which acquired the company on December 4, 2020, in a deal valued at $4.7 billion.
Polled livestock are livestock without horns in species which are normally horned. The term refers to both breeds and strains that are naturally polled through selective breeding and also to naturally horned animals that have been disbudded. Natural polling occurs in cattle, yaks, water buffalo, and goats, and in these animals it affects both sexes equally; in sheep, by contrast, both sexes may be horned, both polled, or only the females polled. The history of breeding polled livestock starts about 6000 years BC.
Illumina, Inc. is an American biotechnology company, headquartered in San Diego, California. Incorporated on April 1, 1998, Illumina develops, manufactures, and markets integrated systems for the analysis of genetic variation and biological function. The company provides a line of products and services that serves the sequencing, genotyping and gene expression, and proteomics markets, and serves more than 155 countries.
23andMe Holding Co. is an American personal genomics and biotechnology company based in South San Francisco, California. It is best known for providing a direct-to-consumer genetic testing service in which customers provide a saliva sample that is laboratory analysed, using single nucleotide polymorphism genotyping, to generate reports relating to the customer's ancestry and genetic predispositions to health-related topics. The company's name is derived from the 23 pairs of chromosomes in a diploid human cell.
Genetically modified animals are animals that have been genetically modified for a variety of purposes including producing drugs, enhancing yields, increasing resistance to disease, etc. The vast majority of genetically modified animals are at the research stage while the number close to entering the market remains small.
Brandon Ross Colby is an American medical geneticist in Beverly Hills, California and physician specializing in predictive medicine and genetic testing. He is author of Outsmart Your Genes, a book about genetics published in 2011, and he is the founder and CEO of direct-to-consumer genetic testing service Sequencing.
WeWork Inc. is a provider of coworking spaces, including physical and virtual shared spaces, headquartered in New York City. As of December 31, 2022, the company operated 43.9 million square feet (4,080,000 m2) of space, including 18.3 million square feet (1,700,000 m2) in the United States and Canada, in 779 locations in 39 countries, and had 547,000 members, with a weighted average commitment term of 19 months.
Sophia Christina Amoruso is an American businesswoman. Amoruso founded Nasty Gal, a women's fashion retailer, which went on to be named one of "the fastest growing companies" by Inc. Magazine in 2012. In 2016, she was named one of the richest self-made women in the world by Forbes. However, Nasty Gal filed for bankruptcy. In 2017, Amoruso founded Girlboss Media, a company that creates content for women in the millennial generation to progress as people in their personal and professional life.
MOD Pizza is an American fast-casual pizza restaurant chain based in Seattle, Washington. Founded in 2008, MOD has more than 560 locations as of December 2023 in the United States and two locations in Canada.
Alison L. Van Eenennaam is a Cooperative Extension Specialist in the Department of Animal Science at the University of California, Davis and runs the Animal Genomics and Biotechnology Laboratory. She has served on national committees such as the USDA National Advisory Committee on Biotechnology in the 21st Century (AC21) and was awarded the 2014 Borlaug CAST Communication Award. Van Eenennaam writes the Biobeef Blog.
Byju's is an Indian multinational educational technology company, headquartered in Bengaluru. It was founded in 2011 by Byju Raveendran and Divya Gokulnath. As of October 2024, various media outlets reported that Byju's valuation has now plummeted to zero, down from its peak valuation of $22 billion in 2022. In April 2023, the company claimed it had over 150 million registered students.
Intellia Therapeutics, Inc. is an American clinical-stage biotechnology company focused on developing novel, potentially curative therapeutics leveraging CRISPR-based technologies. The company's in vivo programs use intravenously administered CRISPR as the therapy, in which the company's proprietary delivery technology enables highly precise editing of disease-causing genes directly within specific target tissues. Intellia's ex vivo programs use CRISPR to create the therapy by using engineered human cells to treat cancer and autoimmune diseases.
Ginkgo Bioworks is an American biotech company founded in 2008 by five scientists from MIT, headed by Jason Kelly. The company specializes in using genetic engineering to produce bacteria with industrial applications for other biotech companies, saving other companies the cost of reproducing the initial stages of design in synthetic biology. The self-proclaimed "Organism Company" was one of the world's largest privately held biotech companies, valued at $4.2 billion in 2019. It raised $290 million in September and $350 million in October of that year. Ginkgo Bioworks went public on the New York Stock Exchange via a SPAC merger on September 17, 2021.
Nu Ride Inc. is an American electric vehicle automaker located in Lordstown, Ohio. The company was based at the Lordstown Assembly plant, previously a General Motors factory. Lordstown Motors was known for its Lordstown Endurance electric pickup truck. In March 2024, the company emerged from its September 2023 bankruptcy restructuring as Nu Ride Inc., headquartered in New York City.