This article may be confusing or unclear to readers.(November 2017) |
Biological engineering or bioengineering is the application of principles of biology and the tools of engineering to create usable, tangible, economically viable products. [1] Biological engineering employs knowledge and expertise from a number of pure and applied sciences, [2] such as mass and heat transfer, kinetics, biocatalysts, biomechanics, bioinformatics, separation and purification processes, bioreactor design, surface science, fluid mechanics, thermodynamics, and polymer science. It is used in the design of medical devices, diagnostic equipment, biocompatible materials, renewable energy, ecological engineering, agricultural engineering, process engineering and catalysis, and other areas that improve the living standards of societies.
Examples of bioengineering research include bacteria engineered to produce chemicals, new medical imaging technology, portable and rapid disease diagnostic devices, prosthetics, biopharmaceuticals, and tissue-engineered organs. [3] [4] Bioengineering overlaps substantially with biotechnology and the biomedical sciences in a way analogous to how various other forms of engineering and technology relate to various other sciences (such as aerospace engineering and other space technology to kinetics and astrophysics).[ citation needed ]
In general, biological engineers attempt to mimic biological systems to create products or modify and control biological systems. Working with doctors, clinicians, and researchers, bioengineers use traditional engineering principles and techniques to address biological processes, including ways to replace, augment, sustain, or predict chemical and mechanical processes. [5] [6]
Biological engineering is a science-based discipline founded upon the biological sciences in the same way that chemical engineering, electrical engineering, and mechanical engineering [7] can be based upon chemistry, electricity and magnetism, and classical mechanics, respectively. [8]
Before WWII, biological engineering had begun being recognized as a branch of engineering and was a new concept to people. Post-WWII, it grew more rapidly, and the term "bioengineering" was coined by British scientist and broadcaster Heinz Wolff in 1954 at the National Institute for Medical Research. Wolff graduated that year and became the Division of Biological Engineering director at Oxford. This was the first time Bioengineering was recognized as its own branch at a university. The early focus of this discipline was electrical engineering due to the work with medical devices and machinery during this time. [9]
When engineers and life scientists started working together, they recognized that the engineers did not know enough about the actual biology behind their work. To resolve this problem, engineers who wanted to get into biological engineering devoted more time to studying the processes of biology, psychology, and medicine. [10]
More recently, the term biological engineering has been applied to environmental modifications such as surface soil protection, slope stabilization, watercourse and shoreline protection, windbreaks, vegetation barriers including noise barriers and visual screens, and the ecological enhancement of an area. Because other engineering disciplines also address living organisms, the term biological engineering can be applied more broadly to include agricultural engineering.[ citation needed ]
The first biological engineering program in the United States was started at University of California, San Diego in 1966. [11] More recent programs have been launched at MIT [12] and Utah State University. [13] Many old agricultural engineering departments in universities over the world have re-branded themselves as agricultural and biological engineering or agricultural and biosystems engineering . According to Professor Doug Lauffenburger of MIT, [12] [14] biological engineering has a broad base which applies engineering principles to an enormous range of size and complexities of systems, ranging from the molecular level (molecular biology, biochemistry, microbiology, pharmacology, protein chemistry, cytology, immunology, neurobiology and, neuroscience) to cellular and tissue-based systems (including devices and sensors), to whole macroscopic organisms (plants, animals), and even to biomes and ecosystems.
The average length of study is three to five years, and the completed degree is signified as a bachelor of engineering (B.S. in engineering). Fundamental courses include thermodynamics, biomechanics, biology, genetic engineering, fluid and mechanical dynamics, chemical and enzyme kinetics, electronics, and materials properties. [15] [16]
Depending on the institution and particular definitional boundaries employed, some major branches of bioengineering may be categorized as (note these may overlap):
Biomedical engineering (BME) or medical engineering is the application of engineering principles and design concepts to medicine and biology for healthcare applications. BME is also traditionally logical sciences to advance health care treatment, including diagnosis, monitoring, and therapy. Also included under the scope of a biomedical engineer is the management of current medical equipment in hospitals while adhering to relevant industry standards. This involves procurement, routine testing, preventive maintenance, and making equipment recommendations, a role also known as a Biomedical Equipment Technician (BMET) or as a clinical engineer.
Biomechanics is the study of the structure, function and motion of the mechanical aspects of biological systems, at any level from whole organisms to organs, cells and cell organelles, using the methods of mechanics. Biomechanics is a branch of biophysics.
Biochemical engineering, also known as bioprocess engineering, is a field of study with roots stemming from chemical engineering and biological engineering. It mainly deals with the design, construction, and advancement of unit processes that involve biological organisms or organic molecules and has various applications in areas of interest such as biofuels, food, pharmaceuticals, biotechnology, and water treatment processes. The role of a biochemical engineer is to take findings developed by biologists and chemists in a laboratory and translate that to a large-scale manufacturing process.
The American Society of Agricultural and Biological Engineers (ASABE) is an international professional society devoted to agricultural and biological engineering. It was founded in December 1907 at the University of Wisconsin–Madison as the American Society of Agricultural Engineers (ASAE) and is now based in St. Joseph, Michigan. Today the organization has about 9,000 members in over 100 countries. ASABE serves many functions: it provides a forum for communication of research findings through conferences, scientific journals, and a magazine; it develops standards of practice; it provides opportunities for members to network. It cooperates with the Alpha Epsilon honor society.
A Bachelor of Science in Biomedical Engineering is a kind of bachelor's degree typically conferred after a four-year undergraduate course of study in biomedical engineering (BME). The degree itself is largely equivalent to a Bachelor of Science and many institutions conferring degrees in the fields of biomedical engineering and bioengineering do not append the field to the degree itself. Courses of study in BME are also extremely diverse as the field itself is relatively new and developing. In general, an undergraduate course of study in BME is likened to a cross between engineering and biological science with varying degrees of proportionality between the two.
Peter W. Zandstra, is a Canadian scientist who is the Director of the Michael Smith Laboratories at the University of British Columbia.
Biological systems engineering or biosystems engineering is a broad-based engineering discipline with particular emphasis on non-medical biology. It can be thought of as a subset of the broader notion of biological engineering or bio-technology though not in the respects that pertain to biomedical engineering as biosystems engineering tends to focus less on medical applications than on agriculture, ecosystems, and food science. The discipline focuses broadly on environmentally sound and sustainable engineering solutions to meet societies' ecologically related needs. Biosystems engineering integrates the expertise of fundamental engineering fields with expertise from non-engineering disciplines.
Biomechanical engineering, also considered a subfield of mechanical engineering and biomedical engineering, combines principles of physics, biology, and engineering. Topics of interest in this field include biomechanics, computational mechanics, continuum mechanics, bioinstrumentation, design of implants and prostheses, etc. This is a highly multidisciplinary field, and engineers with such a background may enter related niche careers, e.g., as an ergonomics consultant, rehabilitation engineer, biomechanics researcher, and biomedical device engineer.
Linda Gay Griffith is an American biological engineer, and Professor of Biological Engineering and Mechanical Engineering at Massachusetts Institute of Technology, where she also directs the Center for Gynepathology Research.
Duane Frederick Bruley is an American researcher, entrepreneur, and academician.
Robert M. Nerem, often referred to as Bob Nerem, a member of the U. S. National Academy of Engineering and the Institute of Medicine, held the Parker H. Petit Distinguished Chair for Engineering in Medicine and Institute Professor Emeritus at the Georgia Institute of Technology where he was an Emeritus Professor until his death.
Tony Jun Huang is the William Bevan Distinguished Professor of Mechanical Engineering and Materials Science at Duke University, United States.
Akhilesh K. Gaharwar is an Indian academic and a professor in the Department of Biomedical Engineering at Texas A&M University.
David A. Vorp is an American bioengineer, researcher, entrepreneur, and academic administrator noted for his contributions to aortic aneurysm biomechanics and pathobiology, and tissue engineered vascular grafts. He currently holds the titles of Associate Dean for Research at the University of Pittsburgh Swanson School of Engineering and the John A. Swanson Professor of Bioengineering, with secondary appointments in the departments of Cardiothoracic Surgery, Surgery, Chemical & Petroleum Engineering, and the Clinical & Translational Sciences Institute at the University of Pittsburgh. He also serves as the co-director of the Center for Medical Innovation., the acting director of the university's GRID Institute, and the director of the Vascular Bioengineering Laboratory.
Beth L. Pruitt is an American engineer. Upon completing her master's degree in manufacturing systems engineering from Stanford University, Pruitt served as an officer in the United States Navy. She is a full professor of mechanical engineering, biological engineering, and biomolecular science & engineering at the University of California, Santa Barbara. She is a fellow of both ASME and AIMBE.
Farshid Guilak is an American engineer and orthopedic researcher. He is the Mildred B. Simon Professor of Orthopaedic Surgery at Washington University in St. Louis and director of research at Shriners Hospitals for Children. He is also on the faculty of the departments of Biomedical Engineering, Mechanical Engineering & Materials Science, and Developmental Biology at Washington University.
Pavlos P. Vlachos is a Greek-American engineer, scientist, academic, and entrepreneur. He is professor in Purdue’s School of Mechanical Engineering and in the Weldon School of Biomedical Engineering, and the St. Vincent Health Professor of Healthcare Engineering. He serves as the Director for the Purdue Regenstrief Center for Healthcare Engineering (RCHE).
Dawn M. Elliott is an American biomedical engineer whose research concerns the biomechanics of connective tissue including the tendons, menisci, and intervertebral discs. She is Blue and Gold Distinguished Professor of Biomedical Engineering at the University of Delaware, adjunct professor of orthopaedic surgery at the Perelman School of Medicine at the University of Pennsylvania, and the former president of the Biomedical Engineering Society.
Laurel Kuxhaus is an American biomechanical engineer whose research focuses on the mechanics of soft and hard tissues in joints such as the elbow and ankle, and the effects of injuries on those joints. She is a professor of mechanical and aerospace engineering in the Wallace H. Coulter School of Engineering at Clarkson University.
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