Resuscitation Outcomes Consortium

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The Resuscitation Outcomes Consortium (ROC) is a network of eleven regional clinical centers and a data coordinating center. The consortium conducts experimental and observational studies of out-of-hospital treatments of cardiac arrest and trauma. Ten communities in the United States and Canada doing uniform quality improvement, clinical trials, and tracking of cardiac arrest and major trauma. The network is coordinated by the University of Washington Clinical Trial Center. ROC is funded by the National Heart, Lung, and Blood Institute, Institute of Circulatory and Respiratory Health, United States Army Medical Research and Materiel Command, Defence Research and Development Canada, Heart and Stroke Foundation of Canada, and American Heart Association.

Contents

Research Sites

SiteRegional Clinical CenterService Area PopulationResidents per Square MileNo. of EMS AgenciesNo. of Hospitals
Alabama, United States (Central and Northern)Alabama Resuscitation Center644,7014851314
Dallas, Texas, United States (includes some surrounding cities)Dallas Center for Resuscitation Research1,989,3573,1731122
Iowa, United States (participated in the network from September 2004 to February 2008)University of Iowa Carver College of Medicine-Iowa Resuscitation Network1,015,3473881919
Milwaukee, Wisconsin, United StatesThe Milwaukee Resuscitation Research Center940,1643,8851616
Ottawa, Ontario, Canada (includes 20 other cities in the OPALS group)Ottawa/OPALS/British Columbia RCC4,030,6963143937
Pittsburgh, Pennsylvania, United States (includes some suburbs)Pittsburgh Resuscitation Network935,967396638
Portland, Oregon, United States (includes 4 counties in Oregon and Washington)Oregon Health & Sciences University - Portland Resuscitation Outcomes Consortium1,751,1194311516
San Diego, California, United States (includes the entire county)UCSD/San Diego Resuscitation Research Center
Seattle/King County, Washington, United StatesSeattle-King County Center for Resuscitation Research at the University of Washington1,666,9781,5733518
Toronto, Ontario, Canada (includes surrounding areas)Toronto Regional Resuscitation Research Out of Hospital Network5,627,0219113255
Vancouver, British Columbia, CanadaOttawa/OPALS/British Columbia RCC2,779,3731,6043933

Studies

Epistry Database

Jama 2008 number of cardiac arrests.png
Number of cases of EMS-assessed and EMS-treated cardiac arrest and cardiac arrests with initial recorded rhythm being shockable.
Jama cardiac arrest survival rates.png
Survival rates for the period May 1, 2006 to April 30, 2007


Hypertonic Saline

ROC PRIMED

(Prehospital Resuscitation using an IMpedance valve and Early vs Delayed analysis) Seattle/King County did not participate in the early vs. delayed analysis portion of the trial. [1]

CPR Feedback


Related Research Articles

<span class="mw-page-title-main">Cardiac arrest</span> Sudden failure of heart beat

Cardiac arrest, also known as sudden cardiac arrest, is when the heart suddenly and unexpectedly stops beating. As a result, blood cannot properly circulate around the body and there is diminished blood flow to the brain and other organs. When the brain does not receive enough blood, this can cause a person to lose consciousness. Coma and persistent vegetative state may result from cardiac arrest. Cardiac arrest is also identified by a lack of central pulses and abnormal or absent breathing.

<span class="mw-page-title-main">Cardiopulmonary resuscitation</span> Emergency procedure after sudden cardiac arrest

Cardiopulmonary resuscitation (CPR) is an emergency procedure consisting of chest compressions often combined with artificial ventilation, or mouth to mouth in an effort to manually preserve intact brain function until further measures are taken to restore spontaneous blood circulation and breathing in a person who is in cardiac arrest. It is recommended for those who are unresponsive with no breathing or abnormal breathing, for example, agonal respirations.

<span class="mw-page-title-main">Advanced cardiac life support</span> Emergency medical care

Advanced cardiac life support, advanced cardiovascular life support (ACLS) refers to a set of clinical guidelines established by the American Heart Association (AHA) for the urgent and emergent treatment of life-threatening cardiovascular conditions that will cause or have caused cardiac arrest, using advanced medical procedures, medications, and techniques. ACLS expands on Basic Life Support (BLS) by adding recommendations on additional medication and advanced procedure use to the CPR guidelines that are fundamental and efficacious in BLS. ACLS is practiced by advanced medical providers including physicians, some nurses and paramedics; these providers are usually required to hold certifications in ACLS care.

<span class="mw-page-title-main">Defibrillation</span> Treatment for life-threatening cardiac arrhythmias

Defibrillation is a treatment for life-threatening cardiac arrhythmias, specifically ventricular fibrillation (V-Fib) and non-perfusing ventricular tachycardia (V-Tach). A defibrillator delivers a dose of electric current to the heart. Although not fully understood, this process depolarizes a large amount of the heart muscle, ending the arrhythmia. Subsequently, the body's natural pacemaker in the sinoatrial node of the heart is able to re-establish normal sinus rhythm. A heart which is in asystole (flatline) cannot be restarted by a defibrillator; it would be treated only by cardiopulmonary resuscitation (CPR) and medication, and then by cardioversion or defibrillation if it converts into a shockable rhythm.

<span class="mw-page-title-main">Do not resuscitate</span> Legal order saying not to perform CPR if heart stops

A do-not-resuscitate order (DNR), also known as Do Not Attempt Resuscitation (DNAR), Do Not Attempt Cardiopulmonary Resuscitation (DNACPR), no code or allow natural death, is a medical order, written or oral depending on the jurisdiction, indicating that a person should not receive cardiopulmonary resuscitation (CPR) if that person's heart stops beating. Sometimes these decisions and the relevant documents also encompass decisions around other critical or life-prolonging medical interventions. The legal status and processes surrounding DNR orders vary in different polities. Most commonly, the order is placed by a physician based on a combination of medical judgement and patient involvement.

The Seattle & King County Emergency Medical Services System is a fire-based two-tier response system providing prehospital basic and advanced life support services.

<span class="mw-page-title-main">Major trauma</span> Injury that could cause prolonged disability or death

Major trauma is any injury that has the potential to cause prolonged disability or death. There are many causes of major trauma, blunt and penetrating, including falls, motor vehicle collisions, stabbing wounds, and gunshot wounds. Depending on the severity of injury, quickness of management, and transportation to an appropriate medical facility may be necessary to prevent loss of life or limb. The initial assessment is critical, and involves a physical evaluation and also may include the use of imaging tools to determine the types of injuries accurately and to formulate a course of treatment.

<span class="mw-page-title-main">Traumatic cardiac arrest</span> Medical condition

Traumatic cardiac arrest (TCA) is a condition in which the heart has ceased to beat due to blunt or penetrating trauma, such as a stab wound to the thoracic area. It is a medical emergency which will always result in death without prompt advanced medical care. Even with prompt medical intervention, survival without neurological complications is rare. In recent years, protocols have been proposed to improve survival rate in patients with traumatic cardiac arrest, though the variable causes of this condition as well as many coexisting injuries can make these protocols difficult to standardize. Traumatic cardiac arrest is a complex form of cardiac arrest often derailing from advanced cardiac life support in the sense that the emergency team must first establish the cause of the traumatic arrest and reverse these effects, for example hypovolemia and haemorrhagic shock due to a penetrating injury.

<span class="mw-page-title-main">ABC (medicine)</span> Mnemonic for Airway, Breathing, and Circulation

ABC and its variations are initialism mnemonics for essential steps used by both medical professionals and lay persons when dealing with a patient. In its original form it stands for Airway, Breathing, and Circulation. The protocol was originally developed as a memory aid for rescuers performing cardiopulmonary resuscitation, and the most widely known use of the initialism is in the care of the unconscious or unresponsive patient, although it is also used as a reminder of the priorities for assessment and treatment of patients in many acute medical and trauma situations, from first-aid to hospital medical treatment. Airway, breathing, and circulation are all vital for life, and each is required, in that order, for the next to be effective: a viable Airway is necessary for Breathing to provide oxygenated blood for Circulation. Since its development, the mnemonic has been extended and modified to fit the different areas in which it is used, with different versions changing the meaning of letters or adding other letters.

<span class="mw-page-title-main">AutoPulse</span> Cardiopulmonary resuscitation device

The AutoPulse is an automated, portable, battery-powered cardiopulmonary resuscitation device created by Revivant and subsequently purchased and currently manufactured by ZOLL Medical Corporation. It is a chest compression device composed of a constricting band and half backboard that is intended to be used as an adjunct to CPR during advanced cardiac life support by professional health care providers. The AutoPulse uses a distributing band to deliver the chest compressions. In literature it is also known as LDB-CPR.

Door-to-balloon is a time measurement in emergency cardiac care (ECC), specifically in the treatment of ST segment elevation myocardial infarction. The interval starts with the patient's arrival in the emergency department, and ends when a catheter guidewire crosses the culprit lesion in the cardiac cath lab. Because of the adage that "time is muscle", meaning that delays in treating a myocardial infarction increase the likelihood and amount of cardiac muscle damage due to localised hypoxia, ACC/AHA guidelines recommend a door-to-balloon interval of no more than 90 minutes. As of 2006 in the United States, fewer than half of STEMI patients received reperfusion with primary percutaneous coronary intervention (PCI) within the guideline-recommended timeframe. It has become a core quality measure for the Joint Commission on Accreditation of Healthcare Organizations (TJC).

Early goal-directed therapy was introduced by Emanuel P. Rivers in The New England Journal of Medicine in 2001 and is a technique used in critical care medicine involving intensive monitoring and aggressive management of perioperative hemodynamics in patients with a high risk of morbidity and mortality. In cardiac surgery, goal-directed therapy has proved effective when commenced after surgery. The combination of GDT and Point-of-Care Testing has demonstrated a marked decrease in mortality for patients undergoing congenital heart surgery. Furthermore, a reduction in morbidity and mortality has been associated with GDT techniques when used in conjunction with an electronic medical record.

Targeted temperature management (TTM) previously known as therapeutic hypothermia or protective hypothermia is an active treatment that tries to achieve and maintain a specific body temperature in a person for a specific duration of time in an effort to improve health outcomes during recovery after a period of stopped blood flow to the brain. This is done in an attempt to reduce the risk of tissue injury following lack of blood flow. Periods of poor blood flow may be due to cardiac arrest or the blockage of an artery by a clot as in the case of a stroke.

The Utstein Style is a set of guidelines for uniform reporting of cardiac arrest. The Utstein Style was first proposed for emergency medical services in 1991. The name derives from a 1990 conference of the European Society of Cardiology, the European Academy of Anesthesiology, the European Society for Intensive Care Medicine, and related national societies, held at the Utstein Abbey on the island of Mosterøy, Norway.

The Ontario Prehospital Advanced Life Support (OPALS) Studies were a series of multi-center before-and-after clinical trials looking at the impact of prehospital advanced life support services. The studies have not found the addition of advanced life support services to increase survival to hospital discharge for cardiac arrest patients.

Return of spontaneous circulation (ROSC) is the resumption of a sustained heart rhythm that perfuses the body after cardiac arrest. It is commonly associated with significant respiratory effort. Signs of return of spontaneous circulation include breathing, coughing, or movement and a palpable pulse or a measurable blood pressure. Someone is considered to have sustained return of spontaneous circulation when circulation persists and cardiopulmonary resuscitation has ceased for at least 20 consecutive minutes.

An inspiratory impedance threshold device is a valve used in cardiopulmonary resuscitation (CPR) to decrease intrathoracic pressure and improve venous return to the heart. The valve is a part of a mask or other breathing device such as an endotracheal tube, and may open at high or low pressures

<span class="mw-page-title-main">Rearrest</span>

Rearrest is a phenomenon that involves the resumption of a lethal cardiac dysrhythmia after successful return of spontaneous circulation (ROSC) has been achieved during the course of resuscitation. Survival to hospital discharge rates are as low as 7% for cardiac arrest in general and although treatable, rearrest may worsen these survival chances. Rearrest commonly occurs in the out-of-hospital setting under the treatment of health care providers.

<span class="mw-page-title-main">Benjamin Abella</span> American physician

Benjamin S. Abella is an American physician, emergency medicine practitioner, internist, academic and researcher. He is the William G. Baxt Professor and Vice Chair of Research at University of Pennsylvania’s Department of Emergency Medicine. He directs the Center for Resuscitation Science and the Penn Acute Research Collaboration at the University. He has participated in developing international CPR guidelines.

Post-cardiac arrest syndrome (PCAS) is an inflammatory state of pathophysiology that can occur after a patient is resuscitated from a cardiac arrest. While in a state of cardiac arrest, the body experiences a unique state of global ischemia. This ischemia results in the accumulation of metabolic waste which instigate the production of inflammatory mediators. If return of spontaneous circulation (ROSC) is achieved after CPR, then circulation resumes, resulting in global reperfusion and the subsequent distribution of the ischemia products throughout the body. While PCAS has a unique cause and consequences, it can ultimately be thought of as type of global ischemia-reperfusion injury. The damage, and therefore prognosis, of PCAS generally depends on the length of the patient's ischemic period; therefore the severity of PCAS is not uniform across different patients.

References

  1. "Interview with Keith Lurie M.D. discussing the ResQPOD and the ROC PRIMED trial".