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Robert Steffen | |
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Institutions | University of Zurich |
Robert Steffen is an Emeritus Professor at the Epidemiology, Biostatistics and Prevention Institute, University of Zurich, Switzerland [2] and an adjunct professor at the University of Texas School of Public in Houston. He is an editor of the Journal of Travel Medicine. [3] [4]
Robert Steffen was born and raised in Zurich. He was a medical student at the local university and towards the end of his medical studies, he was elected as the president of the International Federation of Medical Students Association. [5] [6]
He initially trained to become a flight surgeon at the Swiss Air Force Medical Institute. Subsequently, he obtained a broad education in Internal medicine and epidemiology at academic institutions in Sydney, Nairobi, Johannesburg, Chicago, San Francisco, and London.
Steffen's research focused on the epidemiology and prevention of infectious diseases in travelers. Areas of research included malaria, vaccines and travelers’ diarrhea. [7] [8] [9] He conducted a study on the oral antibiotic formulation Rifamycin SV – MMX for treating traveler’s diarrhea and also promoted researches on the interests of older travelers. [10] [11] Lately he focused on a viral infection called Tick-borne encephalitis (TBE). [12] [13] [14]
In the early days of his career, he served as a Chief Border Physician at the Zurich Airport. [15] Steffen served as Chair of the 2018 IHR Emergency Committee and Vice-Chair of the 2014-2016 IHR Emergency Committee for Ebola Virus Disease (EVD). [16] [17] [18] [19] [20] [21] [22] During the Gulf War he was the leader of Task Force Scorpio. [23]
He currently serves as the member of the Swiss Society for Infectious Diseases and an honorary fellow of the Australasian College of Tropical Medicine. [24] [25] Additional award includes the Bronze Medal of the City of Paris and also received the honor of serving as the chairman of the W.H.O. emergency committee. [26] He also has served as the President for International Society of Travel Medicine (ISTM). [27]
An epidemic is the rapid spread of disease to a large number of hosts in a given population within a short period of time. For example, in meningococcal infections, an attack rate in excess of 15 cases per 100,000 people for two consecutive weeks is considered an epidemic.
Arbovirus is an informal name for any virus that is transmitted by arthropod vectors. The term arbovirus is a portmanteau word. Tibovirus is sometimes used to more specifically describe viruses transmitted by ticks, a superorder within the arthropods. Arboviruses can affect both animals and plants. In humans, symptoms of arbovirus infection generally occur 3–15 days after exposure to the virus and last three or four days. The most common clinical features of infection are fever, headache, and malaise, but encephalitis and viral hemorrhagic fever may also occur.
The rifamycins are a group of antibiotics that are synthesized either naturally by the bacterium Amycolatopsis rifamycinica or artificially. They are a subclass of the larger family of ansamycins. Rifamycins are particularly effective against mycobacteria, and are therefore used to treat tuberculosis, leprosy, and mycobacterium avium complex (MAC) infections.
Travelers' diarrhea (TD) is a stomach and intestinal infection. TD is defined as the passage of unformed stool while traveling. It may be accompanied by abdominal cramps, nausea, fever, headache and bloating. Occasionally bloody diarrhea may occur. Most travelers recover within three to four days with little or no treatment. About 12% of people may have symptoms for a week.
Travel medicine or emporiatrics is the branch of medicine that deals with the prevention and management of health problems of international travelers.
Tick-borne encephalitis (TBE) is a viral infectious disease involving the central nervous system. The disease most often manifests as meningitis, encephalitis or meningoencephalitis. Myelitis and spinal paralysis also occurs. In about one third of cases sequelae, predominantly cognitive dysfunction, persist for a year or more.
Tick-borne encephalitis virus (TBEV) is a positive-strand RNA virus associated with tick-borne encephalitis in the genus Flavivirus.
An emerging infectious disease (EID) is an infectious disease whose incidence has increased recently, and could increase in the near future. The minority that are capable of developing efficient transmission between humans can become major public and global concerns as potential causes of epidemics or pandemics. Their many impacts can be economic and societal, as well as clinical. EIDs have been increasing steadily since at least 1940.
Alkhurma virus (ALKV) is a zoonotic virus of the Flaviviridae virus family. ALKV causes Alkhurma hemorrhagic fever (AHF), or alternatively termed as Alkhurma hemorrhagic fever virus, and is mainly based in Saudi Arabia.
Powassan virus (POWV) is a Flavivirus transmitted by ticks, found in North America and in the Russian Far East. It is named after the town of Powassan, Ontario, where it was identified in a young boy who eventually died from it. It can cause encephalitis, inflammation of the brain. No approved vaccine or antiviral drug exists. Prevention of tick bites is the best precaution.
Ehrlichiosis is a tick-borne bacterial infection, caused by bacteria of the family Anaplasmataceae, genera Ehrlichia and Anaplasma. These obligate intracellular bacteria infect and kill white blood cells.
The International Health Regulations (IHR), first adopted by the World Health Assembly in 1969 and last revised in 2005, are a legally binding rules that only apply to the WHO that is an instrument that aims for international collaboration "to prevent, protect against, control, and provide a public health response to the international spread of disease in ways that are commensurate with and restricted to public health risks and that avoid unnecessary interference with international traffic and trade". The IHR is the only international legal treaty with the responsibility of empowering the World Health Organization (WHO) to act as the main global surveillance system.
Tick-borne encephalitis vaccine is a vaccine used to prevent tick-borne encephalitis (TBE). The disease is most common in Central and Eastern Europe, and Northern Asia. More than 87% of people who receive the vaccine develop immunity. It is not useful following the bite of an infected tick. It is given by injection into a muscle.
Ticks are insects known for attaching to and sucking blood from land-dwelling animals. Ticks fall under the category of 'arthropod', and while they are often thought of in the context of disease transmission, they are also known to cause direct harm to hosts through bites, toxin release, and infestation. Infestation can cause symptoms ranging from mild to severe and may even cause death. Hosts can include any number of vertebrates, though humans and livestock are more likely to be the interest of researchers.
African tick bite fever (ATBF) is a bacterial infection spread by the bite of a tick. Symptoms may include fever, headache, muscle pain, and a rash. At the site of the bite there is typically a red skin sore with a dark center. The onset of symptoms usually occurs 4–10 days after the bite. Complications are rare but may include joint inflammation. Some people do not develop symptoms.
A public health emergency of international concern is a formal declaration by the World Health Organization (WHO) of "an extraordinary event which is determined to constitute a public health risk to other States through the international spread of disease and to potentially require a coordinated international response", formulated when a situation arises that is "serious, sudden, unusual, or unexpected", which "carries implications for public health beyond the affected state's national border" and "may require immediate international action". Under the 2005 International Health Regulations (IHR), states have a legal duty to respond promptly to a PHEIC. The declaration is publicized by an IHR Emergency Committee (EC) of international experts, which was developed following the 2002–2004 SARS outbreak.
Bavarian Nordic A/S is a fully integrated biotechnology company focused on the development, manufacturing and commercialization of vaccines for infectious diseases and cancer immunotherapies. The company is headquartered in Hellerup, Denmark, with a manufacturing facility in Kvistgård, and an additional site in Hørsholm. The company has a research and development facility in Martinsried, Germany, and offices in Zug, Switzerland, and Morrisville, North Carolina. The company uses viral vectors in its research and development.
A monkey bite is the bite of a monkey and is the second most common animal bite after dogs in India. Monkey bites account for 2–21% of animal bite injuries. Monkey bites are an important risk among travelers and after dog bites is the most common animal bite for travelers. Treatment depends upon many factors including the suspicion of rabies. Management involves:
Travel health nursing is a nursing specialty which promotes the health and safety of national and international travelers. Similar to travel medicine, it is an interdisciplinary practice which draws from the knowledge bases of vaccines, epidemiology, tropical medicine, public health, and health education. Travel nursing has experienced an increase in global demand due to the evolution of travel medicine. Travel health nursing was recognized during the 1980s as an emerging occupation to meet the needs of the traveling public, and additional education and training was established. Travel health nurses typically work in "private practice, hospital outpatient units, universities, the government, and the military", and have more opportunities and leadership roles as travel has become more common. However, they also experience organizational and support-related conflicts with general practitioners and patients in healthcare settings.
Global climate change has resulted in a wide range of impacts on the spread of infectious diseases. Like other ways in which climate change affects on human health, climate change exacerbates existing inequalities and challenges in managing infectious disease. Infectious diseases whose transmission can be impacted by climate change include for example the vector-borne diseases dengue fever, malaria, tick-borne diseases, leishmaniasis, zika fever, chikungunya and Ebola virus disease. One of the mechanisms for increased disease transmission is that climate change is altering the geographic range and seasonality of the insects that can carry the diseases.