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Ronald P. Karlsberg | |
|---|---|
| Nationality | American |
| Alma mater | University of California, San Francisco |
| Occupation(s) | Academic Cardiologist |
Ronald P. Karlsberg is an American academic and cardiologist. [1] [2] [3] He is a clinical professor of medicine at the Cedars-Sinai Medical Center and the David Geffen School of Medicine at UCLA, specializing in clinical, preventive, and interventional cardiology. [4]
Karlsberg received his medical degree from the University of California, San Francisco, completed his residency at the University of Colorado Medical Center, and pursued a fellowship in cardiology at Washington University School of Medicine in St. Louis, Missouri. [5]
Karlsberg is board certified in internal medicine, cardiovascular disease, and cardiovascular computed tomography. [5] He is a Master of the Society for Cardiovascular Computed Tomography. [5]
Karlsberg began his career as an academic at the University of California, Irvine, where he served as the director of cardiac wards and research at the Long Beach VA. [5] He later joined the faculty at UCLA and has made contributions in consultative cardiology and clinical research, with a particular focus on coronary artery disease. [5]
Recognized for his work in informatics, Karlsberg created a notable electronic health record system, one of the earliest on the internet. [6] He conducts an masters course in coronary CT angiography and is an expert in advance office-based cardiac imaging. [5] [7]
Karlsberg has been instrumental in leading innovations in areas of cardiovascular research including personal point of care medical devices. [5] [8] [9] He has been an active member of the informatics committee of the American College of Cardiology (ACC) and has contributed to the development of national electronic record standards for cardiac outcomes. [5] He has been on the Board of the Society for Cardiac Computed Tomography (SCCT) establishing standards in that field. The ACC appointed him to the Intersociety Commission for the Accreditation of Computed Tomographic Laboratories (ICACTL). [5]
Karlsberg also co-founded and now serves as chairman of the Cardiovascular Research Foundation of Southern California. [10]
His research interests focuses on translational research in the areas of clinical cardiology, Coronary CT angiography, medical imaging, health informatics, artificial intelligence, point of care medical monitoring, and multicenter medical research trials. [5]
Coronary artery disease (CAD), also called coronary heart disease (CHD), ischemic heart disease (IHD), myocardial ischemia, or simply heart disease, involves the reduction of blood flow to the cardiac muscle due to build-up of atherosclerotic plaque in the arteries of the heart. It is the most common of the cardiovascular diseases. Types include stable angina, unstable angina, and myocardial infarction.
Angiography or arteriography is a medical imaging technique used to visualize the inside, or lumen, of blood vessels and organs of the body, with particular interest in the arteries, veins, and the heart chambers. Modern angiography is performed by injecting a radio-opaque contrast agent into the blood vessel and imaging using X-ray based techniques such as fluoroscopy.
A coronary catheterization is a minimally invasive procedure to access the coronary circulation and blood filled chambers of the heart using a catheter. It is performed for both diagnostic and interventional (treatment) purposes.
A cardiac stress test is a cardiological examination that evaluates the cardiovascular system's response to external stress within a controlled clinical setting. This stress response can be induced through physical exercise or intravenous pharmacological stimulation of heart rate.
An atheroma, or atheromatous plaque, is an abnormal accumulation of material in the inner layer of an arterial wall.
Myocardial perfusion imaging or scanning is a nuclear medicine procedure that illustrates the function of the heart muscle (myocardium).
The Canadian Cardiovascular Society (CCS) is the national voice for cardiovascular physicians and scientists in Canada. The CCS is a membership organization that represents more than 1,800 professionals in the cardiovascular field. Its mission is to promote cardiovascular health and care through knowledge translation, professional development and leadership in health policy.
A coronary CT calcium scan is a computed tomography (CT) scan of the heart for the assessment of severity of coronary artery disease. Specifically, it looks for calcium deposits in atherosclerotic plaques in the coronary arteries that can narrow arteries and increase the risk of heart attack. These plaques are the cause of most heart attacks, and become calcified as they develop.
A myocardial infarction (MI), commonly known as a heart attack, occurs when blood flow decreases or stops in one of the coronary arteries of the heart, causing infarction to the heart muscle. The most common symptom is chest pain or discomfort which may travel into the shoulder, arm, back, neck or jaw. Often such pain occurs in the center or left side of the chest and lasts for more than a few minutes. The discomfort may occasionally feel like heartburn.
A myocardial bridge (MB) is a congenital heart defect in which one of the coronary arteries tunnels through the heart muscle itself (myocardium). In normal patients, the coronary arteries rest on top of the heart muscle and feed blood down into smaller vessels which then take blood into the heart muscle itself. However, if a band of muscle forms around one of the coronary arteries during the fetal stage of development, then a myocardial bridge is formed – a "bridge" of heart muscle over the artery. Each time the heart squeezes to pump blood, the band of muscle exerts pressure and constricts the artery, reducing blood flow to the heart. This defect is present from birth. It is important to note that even a very thin ex. <1 mm and/or short ex. 20 mm MB can cause significant symptoms. MBs can range from a few mm in length to 10 cm or more. The overall prevalence of myocardial bridge is 19%, although its prevalence found by autopsy is much higher (42%).
Spontaneous coronary artery dissection (SCAD) is an uncommon but potentially lethal condition in which one of the coronary arteries that supply the heart, spontaneously develops a blood collection, or hematoma, within the artery wall due to a tear in the wall. SCAD is one of the arterial dissections that can occur.
A diagnosis of myocardial infarction is created by integrating the history of the presenting illness and physical examination with electrocardiogram findings and cardiac markers. A coronary angiogram allows visualization of narrowings or obstructions on the heart vessels, and therapeutic measures can follow immediately. At autopsy, a pathologist can diagnose a myocardial infarction based on anatomopathological findings.
Cardiac magnetic resonance imaging perfusion, also known as stress CMR perfusion, is a clinical magnetic resonance imaging test performed on patients with known or suspected coronary artery disease to determine if there are perfusion defects in the myocardium of the left ventricle that are caused by narrowing of one or more of the coronary arteries.
Coronary CT angiography is the use of computed tomography (CT) angiography to assess the coronary arteries of the heart. The patient receives an intravenous injection of radiocontrast and then the heart is scanned using a high speed CT scanner, allowing physicians to assess the extent of occlusion in the coronary arteries, usually in order to diagnose coronary artery disease.
Cardiac imaging refers to minimally invasive imaging of the heart using ultrasound, magnetic resonance imaging (MRI), computed tomography (CT), or nuclear medicine (NM) imaging with PET or SPECT. These cardiac techniques are otherwise referred to as echocardiography, Cardiac MRI, Cardiac CT, Cardiac PET and Cardiac SPECT including myocardial perfusion imaging.
Overscreening, also called unnecessary screening, is the performance of medical screening without a medical indication to do so. Screening is a medical test in a healthy person who is showing no symptoms of a disease and is intended to detect a disease so that a person may prepare to respond to it. Screening is indicated in people who have some threshold risk for getting a disease, but is not indicated in people who are unlikely to develop a disease. Overscreening is a type of unnecessary health care.
Cardiac allograft vasculopathy (CAV) is a progressive type of coronary artery disease in people who have had a heart transplant. As the donor heart has lost its nerve supply there is typically no chest pain, and CAV is usually detected on routine testing. It may present with symptoms such as tiredness and breathlessness.
John A. Ambrose is an American physician who is an expert in coronary artery disease. He is one of the pioneers in acute coronary syndromes having published over 40 articles in the cardiology literature between 1985 and 2000 on their pathogenesis. He has also published on cigarette smoking and cardiovascular disease. Working with his PhD candidate, Rajat Barua, utilizing a novel in vitro model, they described the effects of cigarette smoking on nitric oxide biosynthesis, endothelial function, and endothelial-derived fibrinolytic and antithrombotic factors. Their 2004 update on cigarette smoking and cardiovascular disease published in the Journal of the American College of Cardiology has been referenced over 2,100 times as of 2020. Ambrose is a Professor of Clinical Medicine at the University of California, San Francisco. He was also a Director of the Cardiac Catheterization Laboratory at Mount Sinai Hospital and received a National Leadership Award from the National Republican Congressional Committee.
Sanjay Rajagopalan is the Herman Hellerstein Professor of Medicine and Chief Scientific and Medical Officer at the Harrington Heart and Vascular Institute, University Hospitals and Professor Medicine at Case Western Reserve University (CWRU) in Cleveland, Ohio. He holds secondary appointments in the Case Western Reserve University Departments of Physiology, Radiology and Biomedical Engineering. Much of his research has been on using technology to guide the detection and treatment of heart disease and more recently on the impact of environmental exposures and climate change on cardiovascular health.
Michelle Claire Williams is a Scottish physician and professor at the University of Edinburgh. She is president elect of the British Society of Cardiovascular Imaging. Her research makes use of medical imaging and machine learning to understand cardiovascular disease.
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