Sara Goodacre | |
---|---|
Born | Sara L. Goodacre |
Alma mater | University of Cambridge (BA) University of Nottingham (PhD) |
Known for | SpiderLab |
Scientific career | |
Fields | Evolutionary genetics Population genetics Conservation genetics Arachnology |
Institutions | University of East Anglia University of Nottingham University of Oxford |
Thesis | Studies on the evolution of Partula (1999) |
Website | arachnotts |
Sara L. Goodacre is a research geneticist and Professor of Evolutionary Biology and Genetics at the University of Nottingham. [1] [2] She is the lead for the Open Air Laboratories, [3] [ Link to precise page ] a citizen science project that engages people with the outdoor environment and Deputy Director of the Biotechnology and Biological Sciences Doctoral Training Programme. [4]
Goodacre studied the Natural Sciences Tripos at the University of Cambridge as a student of Gonville and Caius College, Cambridge, graduating in 1995. [5] Goodacre joined the University of Nottingham for her graduate studies and earned her PhD in 1999 for studies on the evolution of Partula land snails. [6] [5]
Goodacre joined the University of Oxford [7] as a research fellow in 1999. [5] She was a research fellow at the University of East Anglia from 2002. She was described by the BBC as Spider Woman. [8] As of 2018 [update] , Goodacre is based at the University of Nottingham, where she founded the SpiderLab in 2007 and leads the ArachNotts research group. [1] [9] As a geneticist, Goodacre studies the evolution, population and conservation of spiders. [2] She monitored the mating behaviour and sex ratio of the linyphiid spider Pityohyphantes phrygianus with Bengt Gunnarsson at the University of Gothenburg. [1] [10] She also studied the silk of Mygalomorphae spiders and the genetic diversity of spider silk genes [11] [1] and found evidence for antimicrobial activity in the silk of common house spiders. [12] She found that Erigone atra , a pest controlling spider, uses long-distance airborne dispersal. [13] Goodacre contributed to the 2011 book Spider Physiology and Behaviour: Physiology. [14] In 2015 Goodacre reported that spiders could survive "sailing" across oceans. [15]
ArachNotts study the diving bell spider and its silk, which it uses to build a diving bell in which it stores air underwater, and have so far identified some of the silk genes used by this spider. [16] [11] They also work on the relationship between spiders and the microbes that they carry with them, including the mating behaviour and sex-ratio of offspring, the ecology and biological control potential of spiders in agriculture and the use of genetic tools in the conservation of the endangered raft spider. [16]
Goodacre worked alongside chemists at the University of Nottingham to create functionalised spider silk that could be used for drug delivery, wound healing and regenerative medicine. [17] [18] [19] [20] This involved attaching fluorescent dyes and antibiotics by click chemistry to silk synthesised by Escherichia coli . [17] [21] [22] The intention is this synthetic silk can slowly deliver antibiotics or be used as a scaffold to grow new tissues. [23] She has patented the synthesised silk (functionalised spidroin). [24]
Goodacre created the app Spider in da House. [25] She works to make people to be less frightened of spiders, as well as engaging the public in improving the UK's biodiversity. [26] [27] In June 2017, Goodacre took the SpiderLab to a series of primary schools, working in partnership with the Zoological Society of London. [28] She appears regularly on the BBC. [29] [30] [31] [32] [33] She has contributed to The Conversation , The Guardian [34] [35] and serves as an editor of both PeerJ [36] and Heredity . [37]
Thomas Hunt Morgan was an American evolutionary biologist, geneticist, embryologist, and science author who won the Nobel Prize in Physiology or Medicine in 1933 for discoveries elucidating the role that the chromosome plays in heredity.
The brown recluse, Sicariidae is a recluse spider with necrotic venom. Similar to those of other recluse spiders, their bites sometimes require medical attention. The brown recluse is one of three spiders in North America with toxic venom, the others being the black widow and the Chilean recluse.
Spider silk is a protein fibre spun by spiders. Spiders use their silk to make webs or other structures, which function as sticky nets to catch other animals, or as nests or cocoons to protect their offspring, or to wrap up prey. They can also use their silk to suspend themselves, to float through the air, or to glide away from predators. Most spiders vary the thickness and stickiness of their silk for different uses.
Streptomycin is an antibiotic medication used to treat a number of bacterial infections, including tuberculosis, Mycobacterium avium complex, endocarditis, brucellosis, Burkholderia infection, plague, tularemia, and rat bite fever. For active tuberculosis it is often given together with isoniazid, rifampicin, and pyrazinamide. It is administered by injection into a vein or muscle.
Jumping spiders are a group of spiders that constitute the family Salticidae. As of 2019, this family contained over 600 described genera and over 6,000 described species, making it the largest family of spiders at 13% of all species. Jumping spiders have some of the best vision among arthropods and use it in courtship, hunting, and navigation. Although they normally move unobtrusively and fairly slowly, most species are capable of very agile jumps, notably when hunting, but sometimes in response to sudden threats or crossing long gaps. Both their book lungs and tracheal system are well-developed, and they use both systems. Jumping spiders are generally recognized by their eye pattern. All jumping spiders have four pairs of eyes, with the anterior median pair being particularly large.
Latrodectus is a broadly distributed genus of spiders with several species that are commonly known as the true widows. This group is composed of those often loosely called black widow spiders, brown widow spiders, and similar spiders. However, the diversity of species is much greater. A member of the family Theridiidae, this genus contains 34 species, which include several North American "black widows". Besides these, North America also has the red widow Latrodectus bishopi and the brown widow Latrodectus geometricus, which, in addition to North America, has a much wider geographic distribution. Elsewhere, others include the European black widow, the Australian redback spider and the closely related New Zealand katipō, several different species in Southern Africa that can be called button spiders, and the South American black-widow spiders. Species vary widely in size. In most cases, the females are dark-coloured and can be readily identified by reddish markings on the central underside (ventral) abdomen, which are often hourglass-shaped.
Theridiidae, also known as the tangle-web spiders, cobweb spiders and comb-footed spiders, is a large family of araneomorph spiders first described by Carl Jakob Sundevall in 1833. This diverse, globally distributed family includes over 3,000 species in 124 genera, and is the most common arthropod found in human dwellings throughout the world.
Orb-weaver spiders are members of the spider family Araneidae. They are the most common group of builders of spiral wheel-shaped webs often found in gardens, fields, and forests. The English word "orb" can mean "circular", hence the English name of the group. Araneids have eight similar eyes, hairy or spiny legs, and no stridulating organs.
An exudate is a fluid emitted by an organism through pores or a wound, a process known as exuding or exudation. Exudate is derived from exude 'to ooze' from Latin exsūdāre 'to sweat'.
Selman Abraham Waksman was a Jewish Russian-born American inventor, Nobel Prize laureate, biochemist and microbiologist whose research into the decomposition of organisms that live in soil enabled the discovery of streptomycin and several other antibiotics. A professor of biochemistry and microbiology at Rutgers University for four decades, he discovered several antibiotics, and he introduced procedures that have led to the development of many others. The proceeds earned from the licensing of his patents funded a foundation for microbiological research, which established the Waksman Institute of Microbiology located at the Rutgers University Busch Campus in Piscataway, New Jersey (USA). In 1952, he was awarded the Nobel Prize in Physiology or Medicine for "ingenious, systematic, and successful studies of the soil microbes that led to the discovery of streptomycin." Waksman and his foundation later were sued by Albert Schatz, one of his Ph.D. students and the discoverer of streptomycin, for minimizing Schatz's role in the discovery.
BioSteel was a trademark name for a high-strength fiber-based material made of the recombinant spider silk-like protein extracted from the milk of transgenic goats, made by defunct Montreal-based company Nexia Biotechnologies, and later by the Randy Lewis lab of the University of Wyoming and Utah State University. It is reportedly 7-10 times as strong as steel if compared for the same weight, and can stretch up to 20 times its unaltered size without losing its strength properties. It also has very high resistance to extreme temperatures, not losing any of its properties within −20 to 330 degrees Celsius.
Ballooning, sometimes called kiting, is a process by which spiders, and some other small invertebrates, move through the air by releasing one or more gossamer threads to catch the wind, causing them to become airborne at the mercy of air currents and electric fields. A 2018 study concluded that electric fields provide enough force to lift spiders in the air, and possibly elicit ballooning behavior. This is primarily used by spiderlings to disperse; however, larger individuals have been observed doing so as well. The spider climbs to a high point and takes a stance with its abdomen to the sky, releasing fine silk threads from its spinneret until it becomes aloft. Journeys achieved vary from a few metres to hundreds of kilometres. Even atmospheric samples collected from balloons at five kilometres altitude and ships mid-ocean have reported spider landings. Ballooning can be dangerous.
Ambush predators or sit-and-wait predators are carnivorous animals that capture or trap prey via stealth, luring or by strategies utilizing an element of surprise. Unlike pursuit predators, who chase to capture prey using sheer speed or endurance, ambush predators avoid fatigue by staying in concealment, waiting patiently for the prey to get near, before launching a sudden overwhelming attack that quickly incapacitates and captures the prey.
A spider web, spiderweb, spider's web, or cobweb is a structure created by a spider out of proteinaceous spider silk extruded from its spinnerets, generally meant to catch its prey.
A dermal patch or skin patch is a medicated adhesive patch placed on human skin to deliver a medication into the skin. This is in contrast to a transdermal patch, which delivers the medication through the skin and into the bloodstream.
YouTube Space Lab was a 2011–2012 international science competition launched by YouTube and Lenovo, in cooperation with NASA, European Space Agency (ESA), and the Japan Aerospace Exploration Agency (JAXA). Founded by Zahaan Bharmal of Google, the competition challenged teenagers from ages 14–18 to design an experiment to be performed on the International Space Station. The global winners were Amr Mohamed from Alexandria, Egypt, and Dorothy Chen and Sara Ma from Troy, Michigan.
Hydrogels are three-dimensional networks consisting of chemically or physically cross-linked hydrophilic polymers. The insoluble hydrophilic structures absorb polar wound exudates and allow oxygen diffusion at the wound bed to accelerate healing. Hydrogel dressings can be designed to prevent bacterial infection, retain moisture, promote optimum adhesion to tissues, and satisfy the basic requirements of biocompatibility. Hydrogel dressings can also be designed to respond to changes in the microenvironment at the wound bed. Hydrogel dressings should promote an appropriate microenvironment for angiogenesis, recruitment of fibroblasts, and cellular proliferation.
Jeremy was a left-coiled garden snail investigated by biologists. The snail had a rare condition which caused its shell to coil to the left; in most snails the shell coils to the right. At first it was thought to be a rare genetic mutation, although later work revealed that it was likely due to an accident in early development.
Renee Elizabeth Sockett is a professor and microbiologist in the School of Life Sciences at the University of Nottingham. She is a world-leading expert on Bdellovibrio bacteriovorus, a species of predatory bacteria.
Yamni NigamFRES is a professor and scientist at Swansea University. Her scientific research focuses on the immune system of insects and invertebrates. She has a particular interest in wound healing and maggot (larval) therapy. Nigam additionally lectures on anatomy, physiology and pathophysiology within the School of Health & Social Care in the Faculty of Medicine, Health & Life - science at Swansea University.