Scribonius Largus Designatianus (c. 1-c. 50) was the court physician to the Roman emperor Claudius.
About 47 AD, at the request of Gaius Julius Callistus, the emperor's freedman, he drew up a list of 271 prescriptions (Compositiones), most of them his own, although he acknowledged his indebtedness to his tutors, to friends, and to the writings of eminent physicians. [1] Certain traditional remedies are also included. The work has no pretensions to style, and contains many colloquialisms, [2] and has been cited by Peter Suber as a forerunner of Open Access. [3] The greater part of it was transferred without acknowledgment to the work of Marcellus Empiricus (c. 410), De Medicamentis Empiricis, Physicis, et Rationabilibus, which is of great value for the correction of the text of Largus. [4]
See the edition of the Compositiones by S. Sconocchia (Teubner 1983), which replaced the well-outdated edition [5] of G. Helmreich (Teubner 1887).
Largus is credited with an early description peripheral nerve stimulation in the form of shocks from electric fish to provide relief from gout and headaches. [6]
There is an obscure Latin inscription that mentions a "Lucius Scribonius Asclepiades" that Rhodius believed to indicate this Scribonius, but most scholars consider this very doubtful. [7] [8]
Endocrinology is a branch of biology and medicine dealing with the endocrine system, its diseases, and its specific secretions known as hormones. It is also concerned with the integration of developmental events proliferation, growth, and differentiation, and the psychological or behavioral activities of metabolism, growth and development, tissue function, sleep, digestion, respiration, excretion, mood, stress, lactation, movement, reproduction, and sensory perception caused by hormones. Specializations include behavioral endocrinology and comparative endocrinology.
A nerve is an enclosed, cable-like bundle of nerve fibers in the peripheral nervous system.
Neurosurgery or neurological surgery, known in common parlance as brain surgery, is the medical specialty concerned with the surgical treatment of disorders which affect any portion of the nervous system including the brain, spinal cord and peripheral nervous system.
The Hippocratic Oath is an oath of ethics historically taken by physicians. It is one of the most widely known of Greek medical texts. In its original form, it requires a new physician to swear, by a number of healing gods, to uphold specific ethical standards. The oath is the earliest expression of medical ethics in the Western world, establishing several principles of medical ethics which remain of paramount significance today. These include the principles of medical confidentiality and non-maleficence. As the seminal articulation of certain principles that continue to guide and inform medical practice, the ancient text is of more than historic and symbolic value. It is enshrined in the legal statutes of various jurisdictions, such that violations of the oath may carry criminal or other liability beyond the oath's symbolic nature.
Bell's palsy is a type of facial paralysis that results in a temporary inability to control the facial muscles on the affected side of the face. In most cases, the weakness is temporary and significantly improves over weeks. Symptoms can vary from mild to severe. They may include muscle twitching, weakness, or total loss of the ability to move one or, in rare cases, both sides of the face. Other symptoms include drooping of the eyebrow, a change in taste, and pain around the ear. Typically symptoms come on over 48 hours. Bell's palsy can trigger an increased sensitivity to sound known as hyperacusis.
Pedanius Dioscorides, "the father of pharmacognosy", was a Greek physician, pharmacologist, botanist, and author of De materia medica, a 5-volume Greek encyclopedia about herbal medicine and related medicinal substances, that was widely read for more than 1,500 years. For almost two millennia Dioscorides was regarded as the most prominent writer on plants and plant drugs.
The hypoglossal nerve, also known as the twelfth cranial nerve, cranial nerve XII, or simply CN XII, is a cranial nerve that innervates all the extrinsic and intrinsic muscles of the tongue except for the palatoglossus, which is innervated by the vagus nerve. CN XII is a nerve with a sole motor function. The nerve arises from the hypoglossal nucleus in the medulla as a number of small rootlets, pass through the hypoglossal canal and down through the neck, and eventually passes up again over the tongue muscles it supplies into the tongue.
Weakness is a symptom of many different medical conditions. The causes are many and can be divided into conditions that have true or perceived muscle weakness. True muscle weakness is a primary symptom of a variety of skeletal muscle diseases, including muscular dystrophy and inflammatory myopathy. It occurs in neuromuscular junction disorders, such as myasthenia gravis.
A transcutaneous electrical nerve stimulation is a device that produces mild electric current to stimulate the nerves for therapeutic purposes. TENS, by definition, covers the complete range of transcutaneously applied currents used for nerve excitation, but the term is often used with a more restrictive intent—namely, to describe the kind of pulses produced by portable stimulators used to reduce pain. The unit is usually connected to the skin using two or more electrodes which are typically conductive gel pads. A typical battery-operated TENS unit is able to modulate pulse width, frequency, and intensity. Generally, TENS is applied at high frequency (>50 Hz) with an intensity below motor contraction or low frequency (<10 Hz) with an intensity that produces motor contraction. More recently, many TENS units use a mixed frequency mode which alleviates tolerance to repeated use. Intensity of stimulation should be strong but comfortable with greater intensities, regardless of frequency, producing the greatest analgesia. While the use of TENS has proved effective in clinical studies, there is controversy over which conditions the device should be used to treat.
Polyneuropathy is damage or disease affecting peripheral nerves in roughly the same areas on both sides of the body, featuring weakness, numbness, and burning pain. It usually begins in the hands and feet and may progress to the arms and legs and sometimes to other parts of the body where it may affect the autonomic nervous system. It may be acute or chronic. A number of different disorders may cause polyneuropathy, including diabetes and some types of Guillain–Barré syndrome.
The gens Scribonia was a plebeian family of ancient Rome. Members of this gens first appear in history at the time of the Second Punic War, but the first of the Scribonii to obtain the consulship was Gaius Scribonius Curio in 76 BC.
The mental nerve is a sensory nerve of the face. It is a branch of the posterior trunk of the inferior alveolar nerve, itself a branch of the mandibular nerve (CN V3), itself a branch of the trigeminal nerve (CN V). It provides sensation to the front of the chin and the lower lip, as well as the gums of the anterior mandibular (lower) teeth. It can be blocked with local anaesthesia for procedures on the chin, lower lip, and mucous membrane of the inner cheek. Problems with the nerve cause chin numbness.
Theophylact Simocatta was an early seventh-century Byzantine historiographer, arguably ranking as the last historian of Late Antiquity, writing in the time of Heraclius about the late Emperor Maurice (582–602).
Vomiting is the involuntary, forceful expulsion of the contents of one's stomach through the mouth and sometimes the nose.
The Medicina Plinii or Medical Pliny is an anonymous Latin compilation of medical remedies dating to the early 4th century AD. The excerptor, saying that he speaks from experience, offers the work as a compact resource for travelers in dealing with hucksters who sell worthless drugs at exorbitant prices or with know-nothings only interested in profit. The material is presented in three books in the conventional order a capite ad calcem, the first dealing with treatments pertaining to the head and throat, the second the torso and lower extremities, and the third systemic ailments, skin diseases, and poisons.
Philonides was the name of two physicians in the time of Ancient Greece and Rome:
Brachial plexus block is a regional anesthesia technique that is sometimes employed as an alternative or as an adjunct to general anesthesia for surgery of the upper extremity. This technique involves the injection of local anesthetic agents in close proximity to the brachial plexus, temporarily blocking the sensation and ability to move the upper extremity. The subject can remain awake during the ensuing surgical procedure, or they can be sedated or even fully anesthetized if necessary.
Occipital nerve stimulation (ONS), also called peripheral nerve stimulation (PNS) of the occipital nerves, is used to treat chronic migraine patients who have failed to respond to pharmaceutical treatments.
De materia medica is a pharmacopoeia of medicinal plants and the medicines that can be obtained from them. The five-volume work was written between 50 and 70 CE by Pedanius Dioscorides, a Greek physician in the Roman army. It was widely read for more than 1,500 years until supplanted by revised herbals in the Renaissance, making it one of the longest-lasting of all natural history and pharmacology books.
Konstantin Slavin is a Professor and Head of the Department of Stereotactic and functional neurosurgery at the University of Illinois College of Medicine. He is a former president of the American Society for Stereotactic and functional neurosurgery and current vice-president of the World Society for Stereotactic and Functional Neurosurgery. His specialties include Aneurysm, Brain surgery, Brain Tumor, Cerebrovascular Disorders, Craniotomy, Dystonia, Essential Tremor, Facial Nerve Pain, Facial Pain, Glioblastoma, Headache disorders, Laminectomy, Lower back pain, Movement Disorders, Multiple Sclerosis, Neck Pain, Neurosurgery, Neurosurgical Procedures, Pain, Parkinson Disease, Spinal Cord Injuries, and Stroke.