Oswaldo José Guillén Barrios is a Venezuelan-American former professional baseball player who is the current manager of Tiburones de La Guaira of the Venezuelan League. He played in Major League Baseball as a shortstop for 16 seasons, primarily with the Chicago White Sox, from 1985 to 2000. During that time, he won the American League Rookie of the Year Award and also a Gold Glove. He was considered one of the best defensive shortstops of his era. Guillen later managed the Chicago White Sox from 2004 to 2011, winning the World Series in 2005 and then moving to the Miami Marlins in 2012.
Franklyn Miguel Germán Madé is a Dominican former professional baseball relief pitcher. He played in Major League Baseball (MLB) for the Detroit Tigers, Florida Marlins, and Texas Rangers over parts of six seasons.
Anthony Loza Reyes is an American former professional baseball pitcher who played five seasons in Major League Baseball (MLB). He pitched primarily as a starting pitcher for the St. Louis Cardinals and Cleveland Indians. Reyes attended the University of Southern California (USC), before the Cardinals selected him in the 15th round of the 2003 MLB draft, and made his major league debut on August 9, 2005. During his playing career, Reyes threw and batted right-handed, stood 6 feet 2 inches (1.88 m) tall, and weighed 230 pounds (100 kg).
Neal James Cotts is an American former professional baseball pitcher. He played in Major League Baseball (MLB) for the Chicago White Sox, Chicago Cubs, Texas Rangers, Milwaukee Brewers, and Minnesota Twins.
Scott Alan Eyre, is an American former professional baseball left-handed pitcher, who played in Major League Baseball (MLB) for the Chicago White Sox, Toronto Blue Jays, San Francisco Giants, Chicago Cubs, and Philadelphia Phillies.
Gavin Christopher Floyd is an American former professional baseball pitcher, who played in Major League Baseball (MLB) for the Philadelphia Phillies, Chicago White Sox, Atlanta Braves, Cleveland Indians, and Toronto Blue Jays.
David Jeffrey LaPoint is an American former Major League Baseball pitcher. He was the manager of the Rockland Boulders, an American professional baseball team based in Pomona, New York, and member of the Canadian American Association of Professional Baseball known as the Can-Am League.
Mark Bruce Salas is a former professional catcher who played in Major League Baseball from 1984-1991. Salas, who is of Mexican descent, also worked for the Chicago White Sox as a bullpen catcher.
Below is a partial list of minor league baseball players in the Chicago White Sox organizations and rosters of their affiliates:
John Craig "Sonny" Dixon was an American professional baseball pitcher who played in Major League Baseball for four seasons with the Washington Senators (1953–1954), Philadelphia / Kansas City Athletics (1954–1955) and New York Yankees (1956). A right-hander, the switch-hitting Dixon threw stood 6 feet 2 inches (1.88 m) tall and weighed 205 pounds (93 kg).
David Bruce Lundquist Jr. is an American former professional baseball pitcher and former bullpen coach for the Philadelphia Phillies of Major League Baseball (MLB). During his big league playing career, Lundquist pitched for the Chicago White Sox and San Diego Padres.
Simón Alfonseca Castro is a Dominican former professional baseball pitcher. He played in Major League Baseball (MLB) for the Chicago White Sox, Colorado Rockies, and Oakland Athletics.
Thyago Vieira Lucio is a Brazilian professional baseball pitcher for the Arizona Diamondbacks of Major League Baseball (MLB). He has previously played in MLB for the Seattle Mariners, Chicago White Sox, Milwaukee Brewers, and Baltimore Orioles, and in Nippon Professional Baseball (NPB) for the Yomiuri Giants.
Erik Craig Johnson is an American former professional baseball pitcher. He played in Major League Baseball (MLB) for the Chicago White Sox and San Diego Padres.
Scott Alexander Carroll is an American former professional baseball pitcher. He played in Major League Baseball (MLB) for the Chicago White Sox.
Michael Talbert Kopech is an American professional baseball pitcher for the Chicago White Sox of Major League Baseball (MLB). He made his MLB debut in 2018. Kopech bats and throws right-handed.
Deivi Anderson García is a Dominican professional baseball pitcher in the Chicago White Sox organization. He has previously played in Major League Baseball (MLB) for the New York Yankees.
Yermín Francisco Mercedes, nicknamed "the Yermín-ator", is a Dominican professional baseball first baseman, catcher, and designated hitter for the Saraperos de Saltillo of the Mexican League. He has previously played in Major League Baseball (MLB) for the Chicago White Sox and San Francisco Giants. He signed as an international free agent with the Washington Nationals in 2011 and made his MLB debut in 2020 with the White Sox. On April 3, 2021, he set a major league record as the first player in modern MLB history to begin a season with eight consecutive hits. He was named the MLB Rookie of the Month in April 2021.
Zachary Ryan Thompson is an American professional baseball pitcher who is a free agent. He previously played in Major League Baseball (MLB) for the Miami Marlins and Pittsburgh Pirates. He was drafted by the Chicago White Sox in the 5th round of the 2014 Major League Baseball draft.
Davis Alan Martin is an American professional baseball pitcher for the Chicago White Sox of Major League Baseball (MLB). He made his MLB debut in 2022.