Sequence-defined polymer

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Sequence-defined polymer (Syn. sequence-specific polymer, sequence-ordered polymer) is a uniform macromolecule with an exact chain-length and a perfectly defined sequence of monomers. [1] [2] In other words, each monomer unit is at a defined position in the chain e.g. peptides, proteins, oligonucleotides. [3] Sequence-defined polymers constitute therefore a subclass of the field of sequence-controlled polymers. [1] [4]


References

  1. 1 2 Lutz, Jean-François; Ouchi, Makoto; Liu, David R.; Sawamoto, Mitsuo (2013-08-09). "Sequence-Controlled Polymers". Science. 341 (6146) 1238149. doi:10.1126/science.1238149. ISSN   0036-8075. PMID   23929982. S2CID   206549042.
  2. Lutz, Jean-François (2017-12-01). "Defining the Field of Sequence-Controlled Polymers". Macromolecular Rapid Communications. 38 (24): n/a. doi:10.1002/marc.201700582. ISSN   1521-3927. PMID   29160615.
  3. Lehto, Taavi; Wagner, Ernst (2014-12-23). "Sequence-defined polymers for the delivery of oligonucleotides". Nanomedicine. 9 (18): 2843–2859. doi:10.2217/nnm.14.166. PMID   25535686.
  4. Aksakal, R.; Mertens, C.; Soete, M.; Badi, N.; Du Prez, F. (2021). "Applications of Discrete Synthetic Macromolecules in Life and Materials Science: Recent and Future Trends". Advanced Science. 2021 (2004038): 1–22. doi: 10.1002/advs.202004038 . PMC   7967060 . PMID   33747749.