Sheri Krams | |
---|---|
Alma mater | University of California, Davis |
Scientific career | |
Fields | Immunology and abdominal transplantation |
Institutions | Stanford University |
Doctoral advisor | M. Eric Gershwin |
Sheri Michele Krams is an American immunologist and academic administrator serving as the senior associate dean for graduate education and postdoctoral affairs at Stanford University School of Medicine since 2020. She is a professor of surgery specializing in abdominal transplantation.
Krams earned a Ph.D. in immunology from the University of California, Davis in 1989. [1] Her dissertation is titled, Immune Response to the Mitochondrial Autoantigens of Primary Biliary Cirrhosis. [2] M. Eric Gershwin was her doctoral advisor. [2] She completed postdoctoral research in transplantation at the University of California, San Francisco in 1993. [1]
Krams is a professor of surgery specializing in abdominal transplantation at Stanford University School of Medicine. [1] In 2015, she was elected a fellow of the American Society of Transplantation. [1] In 2020, Krams became the senior associate dean for graduate education and postdoctoral affairs. [1] Krams and Olivia M. Martinez manage the transplantation immunology laboratories. [3]
The Stanford University School of Medicine is the medical school of Stanford University and is located in Stanford, California, United States. It traces its roots to the Medical Department of the University of the Pacific, founded in San Francisco in 1858. This medical institution, then called Cooper Medical College, was acquired by Stanford in 1908. The medical school moved to the Stanford campus near Palo Alto, California, in 1959.
Polly Celine Eveline Matzinger is a French-born immunologist who proposed the danger model theory of how the immune system works.
Primary biliary cholangitis (PBC), previously known as primary biliary cirrhosis, is an autoimmune disease of the liver. It results from a slow, progressive destruction of the small bile ducts of the liver, causing bile and other toxins to build up in the liver, a condition called cholestasis. Further slow damage to the liver tissue can lead to scarring, fibrosis, and eventually cirrhosis.
Ursodeoxycholic acid (UDCA), also known as ursodiol, is a secondary bile acid, produced in humans and most other species from metabolism by intestinal bacteria. It is synthesized in the liver in some species, and was first identified in bile of bears of genus Ursus, from which its name derived. In purified form, it has been used to treat or prevent several diseases of the liver or bile ducts.
Deborah Doniach MD FRCP was a British clinical immunologist and pioneer in the field of autoimmune diseases.
Pyruvate dehydrogenase is an enzyme that catalyzes the reaction of pyruvate and a lipoamide to give the acetylated dihydrolipoamide and carbon dioxide. The conversion requires the coenzyme thiamine pyrophosphate.
Elizabeth Hirak Field is an academic scholar and professor in the University of Iowa’s Department of Internal Medicine.
Philippa "Pippa" Marrack, FRS is an English immunologist and academic, based in the United States, best known for her research and discoveries pertaining to T cells. Marrack is the Ida and Cecil Green Professor and chair of the Department of Biomedical Research at National Jewish Health and a distinguished professor of immunology and microbiology at the University of Colorado Denver.
Robert Peter Gale is an American physician and medical researcher. He is known for research in leukemia and other bone marrow disorders.
Cirrhosis, also known as liver cirrhosis or hepatic cirrhosis, and end-stage liver disease, is the impaired liver function caused by the formation of scar tissue known as fibrosis due to damage caused by liver disease. Damage to the liver leads to repair of liver tissue and subsequent formation of scar tissue. Over time, scar tissue can replace normal functioning tissue, leading to the impaired liver function of cirrhosis. The disease typically develops slowly over months or years. Early symptoms may include tiredness, weakness, loss of appetite, unexplained weight loss, nausea and vomiting, and discomfort in the right upper quadrant of the abdomen. As the disease worsens, symptoms may include itchiness, swelling in the lower legs, fluid build-up in the abdomen, jaundice, bruising easily, and the development of spider-like blood vessels in the skin. The fluid build-up in the abdomen may develop into spontaneous infections. More serious complications include hepatic encephalopathy, bleeding from dilated veins in the esophagus, stomach, or intestines, and liver cancer. Stages of cirrhosis include compensated cirrhosis and decompensated cirrhosis.
Hugh O'Neill McDevitt ForMemRS was an immunologist and Professor of Microbiology and Immunology at Stanford University School of Medicine.
C. Garrison Fathman is a Professor of Medicine and Division Chief of Immunology and Rheumatology at Stanford University School of Medicine. He is also the Associate Director of the Institute for Immunity, Transplantation and Infection and Director of the Center for Clinical Immunology at Stanford University. He was Founder and first-President of the Federation of Clinical Immunology Societies. As Director of the CCIS, Dr. Fathman initiated a multidisciplinary approach to study and treat autoimmune diseases, including rheumatoid arthritis, multiple sclerosis, and insulin-dependent diabetes mellitus, and initiated several new approaches to education and community outreach.
Ray David Owen was a teacher and scientist whose discovery of unusual, “mixed,” red blood cell types in cattle twins in 1945 launched the fields of modern immunology and organ transplantation. Owen's 1945 findings were published in the journal Science. This observation demonstrated that self was “learned” by the immune system during development and paved the way for research involving induction of immune tolerance and early tissue grafting. When Frank Macfarlane Burnet and Sir Peter Brian Medawar were awarded their 1960 Nobel Prize in Physiology or Medicine for the discovery of acquired immunological tolerance, Owen was not mentioned in the prize. However, in a letter to Owen, Medawar stated that he believed Owen should have also been included in the prize. Owen also led the successful effort to admit women as California Institute of Technology undergraduates.
Mark Morris Davis is an American immunologist. He is the director of and Avery Family Professor of Immunology at the Institute for Immunity, Transplantation and Infection at Stanford University.
Allan Douglas Kirk, FACS, is chairman of the department of surgery in the Duke University School of Medicine and surgeon-in-chief for Duke University Health System. He is the David C. Sabiston Jr. Professor of Surgery and a professor of immunology and pediatrics. He served as editor-in-chief for the American Journal of Transplantation from 2010 through 2020, and is now Editor Emeritus.
Minnie M. Sarwal is an adult and pediatric nephrologist, researcher of transplant immunology, and biotechnology entrepreneur in San Francisco. She has made significant contributions to the field of organ transplantation, including conducting the first successful complete steroid avoidance trial in the US and the first dosing safety trial for Rituximab in pediatric renal transplantation. She also spearheaded genomic and proteomics investigations into mechanisms of organ transplant injury and was the first to determine that there was substantive molecular heterogeneity in acute kidney transplant rejection. She has successfully commercialized blood testing for early diagnosis of both acute rejection and operational tolerance in kidney transplant patients, providing tools for proactive and predictive immunosuppression monitoring for transplant recipients.
James Michael Millis is an American academic and surgeon specializing in pediatric and adult liver transplantation. He is Professor of Surgery and Vice Chair of Global Surgery at University of Chicago. He is also the director of Clinical Leadership Development Fellowship and Hepatobiliary Surgery at the University of Chicago Medical Center. He is known for developing new techniques of liver surgery that improved outcomes following liver transplantation and non transplant liver and biliary tract surgery.
Donna L. Farber is the Chief of Surgical Sciences, George H. Humphreys, II Professor of Surgical Sciences, and Professor of Microbiology and Immunology at Columbia University. Her research focuses on transplant immunology and memory T-cells.
Cathryn R. Nagler is an American immunologist. She is the Bunning Family Professor in the Pritzker School of Molecular Engineering, the Department of Pathology, and the college at the University of Chicago. Nagler is also the co-founder and president of the startup company ClostraBio, Inc.
Pamela J. Fink is a professor emerita in the Department of Immunology at the University of Washington School of Medicine. Fink was the first woman to be editor-in-chief of the Journal of Immunology, serving from 2013–2018.