Sterol carrier protein

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Sterol carrier protein 2
Identifiers
SymbolSCP2
Pfam PF02036
InterPro IPR003033
PROSITE PDOC00092
SCOP2 1qnd / SCOPe / SUPFAM
OPM superfamily 135
OPM protein 2cx7
Available protein structures:
Pfam   structures / ECOD  
PDB RCSB PDB; PDBe; PDBj
PDBsum structure summary

Sterol carrier proteins (also known as nonspecific lipid transfer proteins) is a family of proteins that transfer steroids and probably also phospholipids and gangliosides between cellular membranes.

Contents

These proteins are different from plant nonspecific lipid transfer proteins but structurally similar to small proteins of unknown function from Thermus thermophilus.

This domain is involved in binding sterols. The human sterol carrier protein 2 (SCP2) is a basic protein that is believed to participate in the intracellular transport of cholesterol and various other lipids. [1]

Human proteins containing this domain

HSD17B4; HSDL2; SCP2; STOML1;

See also

References

  1. Johansson J, Wuthrich K, Szyperski T, Scheek S, Assmann G, Seedorf U (1993). "NMR determination of the secondary structure and the three-dimensional polypeptide backbone fold of the human sterol carrier protein 2". FEBS Lett. 335 (1): 18–26. Bibcode:1993FEBSL.335...18S. doi: 10.1016/0014-5793(93)80431-S . PMID   8243660. S2CID   9969358.
This article incorporates text from the public domain Pfam and InterPro: IPR003033