Bruce Nathan Ames is an American biochemist. He is a professor of Biochemistry and Molecular Biology Emeritus at the University of California, Berkeley, and was a senior scientist at Children's Hospital Oakland Research Institute (CHORI). He is the inventor of the Ames test, a system for easily and cheaply testing the mutagenicity of compounds.
Agmatine, also known as 4-aminobutyl-guanidine, is an aminoguanidine that was discovered in 1910 by Albrecht Kossel. Agmatine is a chemical substance which is naturally created from the amino acid arginine. Agmatine has been shown to exert modulatory action at multiple molecular targets, notably: neurotransmitter systems, ion channels, nitric oxide (NO) synthesis and polyamine metabolism and this provides bases for further research into potential applications.
In organic chemistry, nitrosamines are organic compounds with the chemical structure R2N−N=O, where R is usually an alkyl group. They feature a nitroso group bonded to a deprotonated amine. Most nitrosamines are carcinogenic in nonhuman animals. A 2006 systematic review supports a "positive association between nitrite and nitrosamine intake and gastric cancer, between meat and processed meat intake and gastric cancer and oesophageal cancer, and between preserved fish, vegetable and smoked food intake and gastric cancer, but is not conclusive".
Sir Salvador Moncada, FRS, FRCP, FMedSci is a Honduran-British pharmacologist and professor. He is currently Research Domain Director for Cancer at the University of Manchester.
Chi-Tang Ho is a Chinese-born American food scientist. He received his PhD in organic chemistry in 1974 and started working as a researcher and professor in the food science department at Rutgers University. He is now director of the food science graduate program at Rutgers University in New Brunswick, New Jersey.
Gasotransmitters is a class of neurotransmitters. The molecules are distinguished from other bioactive endogenous gaseous signaling molecules based on a need to meet distinct characterization criteria. Currently, only nitric oxide, carbon monoxide, and hydrogen sulfide are accepted as gasotransmitters.
Exposure science is the study of the contact between humans and harmful agents within their environment – whether it be chemical, physical, biological, behavioural or mental stressors – with the aim of identifying the causes and preventions of the adverse health effects they result in. This can include exposure within the home, workplace, outdoors or any other environment an individual may encounter. The term ‘exposure’ is the umbrella term for many different types, ranging from ultraviolet exposure, exposure to the chemicals in the food we eat, to exposure to long working hours being the occupational factor most attributable to the burden of disease.
Tobin Jay Marks is the Vladimir N. Ipatieff Professor of Catalytic Chemistry, Professor of Material Science and Engineering, Professor of Chemical and Biological Engineering, and Professor of Applied Physics at Northwestern University in Evanston, Illinois. Among the themes of his research are synthetic organo-f-element and early-transition metal organometallic chemistry, polymer chemistry, materials chemistry, homogeneous and heterogeneous catalysis, molecule-based photonic materials, superconductivity, metal-organic chemical vapor deposition, and biological aspects of transition metal chemistry.
Carolyn Ruth Bertozzi is an American chemist and Nobel laureate, known for her wide-ranging work spanning both chemistry and biology. She coined the term "bioorthogonal chemistry" for chemical reactions compatible with living systems. Her recent efforts include synthesis of chemical tools to study cell surface sugars called glycans and how they affect diseases such as cancer, inflammation, and viral infections like COVID-19. At Stanford University, she holds the Anne T. and Robert M. Bass Professorship in the School of Humanities and Sciences. Bertozzi is also an Investigator at the Howard Hughes Medical Institute (HHMI) and is the former Director of the Molecular Foundry, a nanoscience research center at Lawrence Berkeley National Laboratory.
Harden M. McConnell was an American physical chemist. His many awards included the National Medal of Science and the Wolf Prize, and he was elected to the National Academy of Science."
Joseph S. Francisco is an American scientist and the former president of the American Chemical Society from 2009 to 2010. He currently serves as the President's Distinguished Professor of Earth and Environmental Science and Professor of Chemistry at the University of Pennsylvania. He served as the Dean of College of Arts and Sciences, Elmer H. and Ruby M.Cordes Chair in chemistry at University of Nebraska in Lincoln until 2018.
Laura Lee Kiessling is an American chemist and the Novartis Professor of Chemistry at the Massachusetts Institute of Technology. Kiessling's research focuses on elucidating and exploiting interactions on the cell surface, especially those mediated by proteins binding to carbohydrates. Multivalent protein-carbohydrate interactions play roles in cell-cell recognition and signal transduction. Understanding and manipulating these interactions provides tools to study biological processes and design therapeutic treatments. Kiessling's interdisciplinary research combines organic synthesis, polymer chemistry, structural biology, and molecular and cell biology.
John L. Wallace is a medical scientist and was the founder of the Inflammation Research Network at The University of Calgary and inaugural director of the Farncombe Institute at McMaster University. In November 2013, he became the tenth recipient of the Heymans Foundation Memorial Medal. Since its inauguration in 1972, the Medal had been awarded twelve times; six of the recipients are Nobel Laureates. Wallace is also the 2009 recipient of the Premier's Summit Award in Innovation, Canada's largest value research award aimed at supporting the work of an individual scientist.
Yinsheng Wang is a Professor of Chemistry and the Director for the ETOX Graduate Program at the University of California Riverside. His current research involves the use of a multi-pronged approach encompassing mass spectrometry, synthetic chemistry, and molecular biology, for understanding the biological consequences of DNA damage and the molecular mechanisms of actions of anti-cancer drugs and environmental toxicants.
Curtis. C. Harris is the head of the Molecular Genetics and Carcinogenesis Section and chief of the Laboratory of Human Carcinogenesis at the Center for Cancer Research of the National Cancer Institute, NIH.
Umesh Chandra Chaturvedi was an Indian virologist, immunologist, medical microbiologist, CSIR Emeritus Scientist and a former chairman of the Bharat Immunologicals and Biologicals Corporation. The founder head of the department of microbiology at King George's Medical University, he is known for his studies on Dengue virus infection. Chaturvedi is an elected fellow of all the three major Indian science academies viz. Indian Academy of Sciences, National Academy of Sciences, India and the Indian National Science Academy as well as the Royal College of Pathologists and National Academy of Medical Sciences. The Council of Scientific and Industrial Research, the apex agency of the Government of India for scientific research, awarded him the Shanti Swarup Bhatnagar Prize for Science and Technology, one of the highest Indian science awards for his contributions to Medical Sciences in 1981.
Katrina Miranda is an Associate Professor of Biochemistry at the University of Arizona. She works on nitric oxide and their role in diseases like breast cancer, stroke and chronic pain.
Jacquin C. Niles is an American Professor of Biological Engineering and Director of the Massachusetts Institute of Technology Center for Environmental Health Sciences. In an effort to design new antimalarial drugs, Niles studies the malaria parasite and investigates how it interacts with human hosts.
D. Lansing Taylor is the Director at the University of Pittsburgh Drug Discovery Institute (UPDDI), Pennsylvania and a faculty member in the Department of Computational and Systems Biology.
Katherine J. Franz is the Chair of the Department Chemistry at Duke University. She studies metal ion coordination in biological systems and looks to use the insight to manage species such as copper and iron. Franz was awarded the American Chemical Society Award for Encouraging Women into Careers in the Chemical Sciences.
