TMPRSS11B

Last updated
TMPRSS11B
Identifiers
Aliases TMPRSS11B , transmembrane protease, serine 11B, transmembrane serine protease 11B
External IDs HomoloGene: 131255 GeneCards: TMPRSS11B
Gene location (Human)
Ideogram human chromosome 4.svg
Chr. Chromosome 4 (human) [1]
Human chromosome 4 ideogram.svg
HSR 1996 II 3.5e.svg
Red rectangle 2x18.png
Band 4q13.2Start68,226,653 bp [1]
End68,245,720 bp [1]
Orthologs
SpeciesHumanMouse
Entrez

132724

n/a

Ensembl

ENSG00000185873

n/a

UniProt

Q86T26

n/a

RefSeq (mRNA)

NM_182502

n/a

RefSeq (protein)

NP_872308

n/a

Location (UCSC) Chr 4: 68.23 – 68.25 Mb n/a
PubMed search [2] n/a
Wikidata
View/Edit Human

Transmembrane protease, serine 11B is a protein that in humans is encoded by the TMPRSS11B gene. [3]

Protein biological molecule consisting of chains of amino acid residues

Proteins are large biomolecules, or macromolecules, consisting of one or more long chains of amino acid residues. Proteins perform a vast array of functions within organisms, including catalysing metabolic reactions, DNA replication, responding to stimuli, providing structure to cells and organisms, and transporting molecules from one location to another. Proteins differ from one another primarily in their sequence of amino acids, which is dictated by the nucleotide sequence of their genes, and which usually results in protein folding into a specific three-dimensional structure that determines its activity.

Gene basic physical and functional unit of heredity

In biology, a gene is a sequence of nucleotides in DNA or RNA that codes for a molecule that has a function. During gene expression, the DNA is first copied into RNA. The RNA can be directly functional or be the intermediate template for a protein that performs a function. The transmission of genes to an organism's offspring is the basis of the inheritance of phenotypic trait. These genes make up different DNA sequences called genotypes. Genotypes along with environmental and developmental factors determine what the phenotypes will be. Most biological traits are under the influence of polygenes as well as gene–environment interactions. Some genetic traits are instantly visible, such as eye color or number of limbs, and some are not, such as blood type, risk for specific diseases, or the thousands of basic biochemical processes that constitute life.

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References

  1. 1 2 3 GRCh38: Ensembl release 89: ENSG00000185873 - Ensembl, May 2017
  2. ↑ "Human PubMed Reference:".
  3. ↑ "Entrez Gene: Transmembrane protease, serine 11B" . Retrieved 2017-04-03.

Further reading

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