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The Society is an interdisciplinary body of cell biologists, pathologists, anatomists, biochemists, and neuroscientists. HCS's mission[4] is the development and use of visual techniques that provide biochemical and molecular information about the structure and function of cells, tissues and organs and for the dissemination of this knowledge through education and outreach. The Society fulfills its mission through publishing its Journal, the Journal of Histochemistry and Cytochemistry, and through the management of annual meetings and short courses.[5]
The Journal of Histochemistry and Cytochemistry, JHC, publishes primary research on the structure and function of cells, tissues, and organs, as well as mechanisms of development, differentiation, and disease. Of additional importance are new developments in microscopy and imaging, particularly new techniques highlighting current research in genetics, molecular biology and biochemistry. The Journal is published monthly, both in print and online. The Editor-in-Chief, Stephen M. Hewitt (National Cancer Institute) is assisted by a four Associate Editors and an Editorial Board.
The Histochemical Society Newsletter[6] regularly publishes a newsletter that offers updates on meetings, workshops, awards and HCS initiatives. The newsletter is complimentary to all HCS members.
Meetings
The Histochemical Society hosts an annual meeting[5] consisting of scientific plenary talks and symposia, student poster sessions, and an awards presentation and business meeting.
Since becoming a FASEB society in 2011, the HCS annual meetings have been held at Experimental Biology as a guest of another FASEB society. The annual Experimental Biology[7] meeting is among the largest biomedical/research meetings globally. This venue provides our members with many exciting sessions that span a broad spectrum of biomedical research fields.
The HCS also provide assistance to further trainee/student research projects. Specifically, the Capstone Grants[9] for undergraduate students and the Cornerstone Grants[10] for graduate medical trainees and graduate students.
Courses
The HCS founded the Immunohistochemistry and Microscopy Course[11] (IHCM) is course in 2008 and HCS members continue to act as the academic faculty. The IHCM course gives participants extensive hands-on experience with immunohistochemical techniques and a broad range of microscopy imaging modalities. The course emphasizes in-depth theory, didactic lectures, small group discussions, troubleshooting, and informal interactions among faculty and participants. The IHCM course prepares participants to independently carry out immunohistochemistry and imaging in their own laboratories and to critically evaluate and troubleshoot problems that arise when using these techniques.
Advocacy
HCS supports public advocacy of the issues that are important to and affect the biomedical research community through membership in FASEB.
In biochemistry, immunostaining is any use of an antibody-based method to detect a specific protein in a sample. The term "immunostaining" was originally used to refer to the immunohistochemical staining of tissue sections, as first described by Albert Coons in 1941. However, immunostaining now encompasses a broad range of techniques used in histology, cell biology, and molecular biology that use antibody-based staining methods.
Moshe Wolman was an Israeli neuropathologist. He is considered one of the fathers of histochemistry. In 1954, he described Wolman's disease.
Albert Hewett Coons was an American physician, pathologist, and immunologist. He was the first person to conceptualize and develop immunofluorescent techniques for labeling antibodies in the early 1940s.
Cytochemistry is the branch of cell biology dealing with the detection of cell constituents by means of biochemical analysis and visualization techniques. This is the study of the localization of cellular components through the use of staining methods. The term is also used to describe a process of identification of the biochemical content of cells. Cytochemistry is a science of localizing chemical components of cells and cell organelles on thin histological sections by using several techniques like enzyme localization, micro-incineration, micro-spectrophotometry, radioautography, cryo-electron microscopy, X-ray microanalysis by energy-dispersive X-ray spectroscopy, immunohistochemistry and cytochemistry, etc.
A biomedical scientist is a scientist trained in biology, particularly in the context of medical laboratory sciences or laboratory medicine. These scientists work to gain knowledge on the main principles of how the human body works and to find new ways to cure or treat disease by developing advanced diagnostic tools or new therapeutic strategies. The research of biomedical scientists is referred to as biomedical research.
The American Society for Cell Biology (ASCB) is a professional society that was founded in 1960.
The Materials Research Society (MRS) is a non-profit, professional organization for materials researchers, scientists and engineers. Established in 1973, MRS is a member-driven organization of approximately 14,000 materials researchers from academia, industry and government.
The Federation of American Societies for Experimental Biology (FASEB) is a non-profit organization that is the principal umbrella organization of U.S. societies in the field of biological and medical research. This organization organizes academic conferences and publishes scientific literature.
The American Society for Bone and Mineral Research (ASBMR) is a professional, scientific and medical society established in 1977 to promote excellence in bone and mineral research and to facilitate the translation of that research into clinical practice. The ASBMR has a membership of nearly 4,000 physicians, basic research scientists, and clinical investigators from around the world.
The American Physiological Society is a non-profit professional society for physiologists. It has nearly 10,000 members, most of whom hold doctoral degrees in medicine, physiology or other health professions. Its mission is to support research and education in the physiological sciences. The society publishes 16 peer reviewed journals, sponsors scientific conferences, and sponsors awards to further this mission.
The Genetics Society of America (GSA) is a scholarly membership society of more than 5,500 genetics researchers and educators, established in 1931. The Society was formed from the reorganization of the Joint Genetics Sections of the American Society of Zoologists and the Botanical Society of America.
Tissues that have been preserved with formaldehyde, a highly reactive compound, contain a variety of chemical modifications that can reduce the detectability of proteins in biomedical procedures such as immunohistochemistry. Antigen retrieval is an approach to reducing or eliminating these chemical modifications. The two primary methods of antigen retrieval are heat-mediated epitope retrieval (HIER) and proteolytic induced epitope retrieval (PIER).
The Journal of Histochemistry and Cytochemistry is a peer-reviewed scientific journal of cell biology established in 1953. It covers research in the structure and function of cells, tissues, and organs as well as components of development, differentiation, and disease, as well as microscopy and imaging techniques. The journal is the official publication of The Histochemical Society and is published by SAGE Publications. The editor-in-chief as of January 1, 2016 is Stephen M. Hewitt of the National Cancer Institute, National Institutes of Health, in Bethesda Maryland, USA. The immediate past editor-in-chief is John R. Couchman. The journal is published online and in print monthly. Journal content is available for free after twelve months.
The Biological Stain Commission (BSC) is an organization that provides third-party testing and certification of dyes and a few other compounds that are used to enhance contrast in specimens examined in biological and medical laboratories.
The American Society for Investigative Pathology (ASIP) is a society of biomedical scientists who investigate mechanisms of disease. ASIP membership includes scientists in the academic, government, hospital, and pharmaceutical arenas that focus their research on the pathogenesis, classification, diagnosis and manifestations of disease. Research findings are ultimately used in the understanding, diagnosis and treatment of human diseases. The word pathology is derived from the Greek word "pathos" meaning "disease."
Alex Benjamin Novikoff was a Russian Empire-born American biologist who is recognized for his pioneering works in the discoveries of cell organelles. A victim of American Cold War antagonism to communism that he supported, he is also recognized as a public figure of the mid-20th century at the height of McCarthyism in America. As his original discoveries such as cell organelles and autophagy earned other scientists Nobel Prizes, he is regarded as one of the overlooked scientists to get Nobel Prize.
The Australian and New Zealand Bone and Mineral Society (ANZBMS) is a not-for-profit collegiate organisation and principal professional body for scientists and clinicians involved in bone and mineral metabolism research in Australia and New Zealand.
The American Microscopical Society (AMS) is a society of biologists dedicated to promoting the use of microscopy.
Robert J. Cousins is an American nutritional biochemist who has researched the metabolism of heavy metals, especially zinc. He has served as president of the Federation of American Societies for Experimental Biology (FASEB) and the American Society for Nutrition (ASN). He was recognized with membership in the National Academy of Sciences in 2000 and served as editor of the Annual Review of Nutrition for ten years.
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