Titi monkey adenovirus

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Platyrrhini mastadenovirus A
Virus classification Red Pencil Icon.png
(unranked): Virus
Realm: Varidnaviria
Kingdom: Bamfordvirae
Phylum: Preplasmiviricota
Class: Tectiliviricetes
Order: Rowavirales
Family: Adenoviridae
Genus: Mastadenovirus
Platyrrhini mastadenovirus A

Titi monkey adenovirus (TMAdV) is an adenovirus first identified in a New World titi monkey of the genus Callicebus, and the virus also infected at least two humans. [1] It is a large DNA-based virus which can cause death in monkeys, and respiratory illness has been recorded in humans. It was first discovered in Davis, California, at the California National Primate Research Center. The discovery of TMAdV was made by the laboratory of Charles Chiu and the UCSF-Abbott Viral Diagnostics and Discovery Center, [2] using a DNA microarray test called the ViroChip that is able to detect all known as well as novel viruses. The virus is genetically different from any other adenovirus, and the origin or reservoir for TMAdV is still unknown. The significance of the discovery lies in the fact that adenovirus infections have always been thought to be species-specific, and the existence of adenoviruses that can infect both monkeys and humans raises the possibility of zoonotic transmission of adenoviruses.[ citation needed ]

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  1. Chen, Eunice C.; Kristi R. Kelly; Sally P. Mendoza; Nicole Maninger; Ann Rosenthal; Abigail Spinner; Karen L. Bales; David P. Schnurr; Nicholas W. Lerche; Charles Y. Chiu (2011-07-14). "Cross-species transmission of a novel adenovirus associated with a fulminant outbreak in a New World monkey colony". PLOS Pathogens . 7 (7): e1002155. doi:10.1371/journal.ppat.1002155. PMC   3136464 . PMID   21779173.
  2. Chiu, Charles. "UCSF-Abbott Viral Diagnostics and Discovery Center".