The Adventures of Buckaroo Banzai Across the 8th Dimension, often shortened to Buckaroo Banzai, is a 1984 American science fiction film produced and directed by W.D. Richter and written by Earl Mac Rauch. It stars Peter Weller in the title role, with Ellen Barkin, John Lithgow, Jeff Goldblum, and Christopher Lloyd. The supporting cast includes Lewis Smith, Rosalind Cash, Clancy Brown, Pepe Serna, Robert Ito, Vincent Schiavelli, Dan Hedaya, Jonathan Banks, John Ashton, Carl Lumbly and Ronald Lacey.
Jeffrey Scott Buckley, raised as Scott Moorhead, was an American singer, songwriter, and guitarist. After a decade as a session guitarist in Los Angeles, Buckley amassed a following in the early 1990s by performing cover songs at venues in East Village, Manhattan, such as Sin-é, while gradually focusing more on his own material. After rebuffing interest from record labels and Herb Cohen—the manager of his father, singer Tim Buckley— he signed with Columbia, recruited a band, and recorded what would be his only studio album, Grace, in 1994.
The Canada jay, also known as the gray jay, grey jay, camp robber, or whisky jack, is a passerine bird of the family Corvidae. It is found in boreal forests of North America north to the tree line, and in the Rocky Mountains subalpine zone south to New Mexico and Arizona. A fairly large songbird, the Canada jay has pale grey underparts, darker grey upperparts, and a grey-white head with a darker grey nape. It is one of three members of the genus Perisoreus, a genus more closely related to the magpie genus Cyanopica than to other birds known as jays. The Canada jay itself has nine recognized subspecies.
Nicotinamide adenine dinucleotide (NAD) is a coenzyme central to metabolism. Found in all living cells, NAD is called a dinucleotide because it consists of two nucleotides joined through their phosphate groups. One nucleotide contains an adenine nucleobase and the other, nicotinamide. NAD exists in two forms: an oxidized and reduced form, abbreviated as NAD+ and NADH (H for hydrogen), respectively.
Fringe science refers to ideas whose attributes include being highly speculative or relying on premises already refuted. Fringe science theories are often advanced by persons who have no traditional academic science background, or by researchers outside the mainstream discipline. The general public has difficulty distinguishing between science and its imitators, and in some cases a "yearning to believe or a generalized suspicion of experts is a very potent incentive to accepting pseudoscientific claims".
Aubrey David Nicholas Jasper de Grey is an English author and biomedical gerontologist. He is the author of The Mitochondrial Free Radical Theory of Aging (1999) and co-author of Ending Aging (2007). He is known for his view that medical technology may enable human beings alive today not to die from age-related causes. As an amateur mathematician, he has contributed to the study of the Hadwiger–Nelson problem in geometric graph theory, making the first progress on the problem in over 60 years.
Following is a list of topics related to life extension:
The MIT Department of Biology is a center for research and teaching in the life sciences. Many members of the faculty hold joint appointments with other departments at MIT and with outside institutions.
Leonard Pershing Guarente is an American biologist best known for his research on life span extension in the budding yeast Saccharomyces cerevisiae, roundworms, and mice. He is a Novartis Professor of Biology at the Massachusetts Institute of Technology.
David Andrew Sinclair is an Australian-American biologist and academic known for his research on aging and epigenetics. Sinclair is a professor of genetics at Harvard Medical School and is the co-director of its Paul F. Glenn Center for Biology of Aging Research. He is the president of the non-profit Academy for Health & Lifespan Research and an officer of the Order of Australia (AO).
Cynthia Jane Kenyon is an American molecular biologist and biogerontologist known for her genetic dissection of aging in a widely used model organism, the roundworm Caenorhabditis elegans. She is the vice president of aging research at Calico Research Labs, and emeritus professor of biochemistry and biophysics at the University of California, San Francisco (UCSF).
The following outline is provided as an overview of and topical guide to life extension:
Preston "Pete" Wayne Estep III is an American biologist and science and technology advocate. He is a graduate of Cornell University, where he did neuroscience research, and he earned a Ph.D. in Genetics from Harvard University. He did his doctoral research in the laboratory of genomics pioneer Professor George M. Church at Harvard Medical School.
Sirtris Pharmaceuticals, Inc. was a biotechnology company based in Cambridge, MA that developed therapies for type 2 diabetes, cancer, and other diseases. Conceived in 2004 by Harvard University biologist David Sinclair and serial entrepreneur Andrew Perlman, and founded that year by Sinclair and Perlman, along with Christoph Westphal, Richard Aldrich, Richard Pops, and Paul Schimmel, the company was focused on developing Sinclair's research into activators of sirtuins, work that began in the laboratory of Leonard P. Guarente where Sinclair worked as a post-doc before starting his own lab.
Nicanor Robles Austriaco, Jr. OP is a Filipino-American molecular biologist and Catholic priest. He is a professor of biology and professor of theology at Providence College, in Providence, Rhode Island, and a research fellow at the Center for Theology, Religious Studies, and Ethics, at the University of Santo Tomas in the Philippines.
Jan Vijg is the Lola and Saul Kramer Chairperson in Molecular Genetics at the Department of Genetics at the Albert Einstein College of Medicine, New York City, United States. Prior to this appointment, he was a professor at the Buck Institute for Research on Aging.
The disposable soma theory of aging states that organisms age due to an evolutionary trade-off between growth, reproduction, and DNA repair maintenance. Formulated by Thomas Kirkwood, the disposable soma theory explains that an organism only has a limited amount of resources that it can allocate to its various cellular processes. Therefore, a greater investment in growth and reproduction would result in reduced investment in DNA repair maintenance, leading to increased cellular damage, shortened telomeres, accumulation of mutations, compromised stem cells, and ultimately, senescence. Although many models, both animal and human, have appeared to support this theory, parts of it are still controversial. Specifically, while the evolutionary trade-off between growth and aging has been well established, the relationship between reproduction and aging is still without scientific consensus, and the cellular mechanisms largely undiscovered.
The 2018 New York's 14th congressional district election was held on Tuesday, November 6, 2018. The primaries for New York's federal elections were held earlier in the year on June 26. Alexandria Ocasio-Cortez defeated incumbent congressman Joe Crowley in the primary, and went on to defeat Republican opponent Anthony Pappas in the general election.
