Transcranial focused ultrasound

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Transcranial focused ultrasound
Other namestFUS; Transcranial focused ultrasound stimulation
Specialty Psychiatry, neurology
Uses Psychiatric disorders; Neurological disorders

Transcranial focused ultrasound (tFUS) is a form of focused ultrasound (FUS) which is being investigated for the potential non-invasive treatment of psychiatric and neurological disorders. [1] [2] [3] It differs from other non-invasive brain stimulation methods such as magnetic (transcranial magnetic stimulation or TMS) and electrical (transcranial direct-current stimulation or tDCS) in that it has higher spatial resolution and precision (millimetric) and is able to reach deep brain structures. [1] [3] Depending on the parameters, tFUS can inhibit, stimulate, and even ablate brain tissue. [1] Only a handful of clinical studies of tFUS for psychiatric conditions have been conducted as of 2024. [3]

References

  1. 1 2 3 di Biase L, Falato E, Di Lazzaro V (2019). "Transcranial Focused Ultrasound (tFUS) and Transcranial Unfocused Ultrasound (tUS) Neuromodulation: From Theoretical Principles to Stimulation Practices". Front Neurol. 10: 549. doi: 10.3389/fneur.2019.00549 . PMC   6579808 . PMID   31244747.
  2. ↑ Baek H, Lockwood D, Mason EJ, Obusez E, Poturalski M, Rammo R, Nagel SJ, Jones SE (2022). "Clinical Intervention Using Focused Ultrasound (FUS) Stimulation of the Brain in Diverse Neurological Disorders". Front Neurol. 13 880814. doi: 10.3389/fneur.2022.880814 . PMC   9124976 . PMID   35614924.
  3. 1 2 3 Keihani A, Sanguineti C, Chaichian O, Huston CA, Moore C, Cheng C, Janssen SA, Donati FL, Mayeli A, Moussawi K, Phillips ML, Ferrarelli F (October 2024). "Transcranial Focused Ultrasound Neuromodulation in Psychiatry: Main Characteristics, Current Evidence, and Future Directions". Brain Sci. 14 (11): 1095. doi: 10.3390/brainsci14111095 . PMC   11592166 . PMID   39595858.


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