Transmembrane and tetratricopeptide repeat containing 1

Last updated
TMTC1
Identifiers
Aliases TMTC1 , OLF, TMTC1A, ARG99, transmembrane and tetratricopeptide repeat containing 1
External IDs MGI: 3039590 HomoloGene: 65299 GeneCards: TMTC1
Gene location (Human)
Ideogram human chromosome 12.svg
Chr. Chromosome 12 (human) [1]
Human chromosome 12 ideogram.svg
HSR 1996 II 3.5e.svg
Red rectangle 2x18.png
Band 12p11.22Start29,500,840 bp [1]
End29,784,759 bp [1]
Orthologs
SpeciesHumanMouse
Entrez

83857

387314

Ensembl

ENSG00000133687

ENSMUSG00000030306

UniProt

Q8IUR5

Q3UV71

RefSeq (mRNA)

NM_001193451
NM_175861

NM_198967
NM_001347518

RefSeq (protein)

NP_001180380
NP_787057

NP_001334447
NP_945318

Location (UCSC) Chr 12: 29.5 – 29.78 Mb Chr 6: 148.23 – 148.44 Mb
PubMed search [3] [4]
Wikidata
View/Edit Human View/Edit Mouse

Transmembrane and tetratricopeptide repeat containing 1 is a protein that in humans is encoded by the TMTC1 gene. [5]

Protein biological molecule consisting of chains of amino acid residues

Proteins are large biomolecules, or macromolecules, consisting of one or more long chains of amino acid residues. Proteins perform a vast array of functions within organisms, including catalysing metabolic reactions, DNA replication, responding to stimuli, providing structure to cells and organisms, and transporting molecules from one location to another. Proteins differ from one another primarily in their sequence of amino acids, which is dictated by the nucleotide sequence of their genes, and which usually results in protein folding into a specific three-dimensional structure that determines its activity.

Gene basic physical and functional unit of heredity

In biology, a gene is a sequence of nucleotides in DNA or RNA that codes for a molecule that has a function. During gene expression, the DNA is first copied into RNA. The RNA can be directly functional or be the intermediate template for a protein that performs a function. The transmission of genes to an organism's offspring is the basis of the inheritance of phenotypic trait. These genes make up different DNA sequences called genotypes. Genotypes along with environmental and developmental factors determine what the phenotypes will be. Most biological traits are under the influence of polygenes as well as gene–environment interactions. Some genetic traits are instantly visible, such as eye color or number of limbs, and some are not, such as blood type, risk for specific diseases, or the thousands of basic biochemical processes that constitute life.

Related Research Articles

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TMTC4 protein-coding gene in the species Homo sapiens

Transmembrane and Tetratricopeptide repeat containing 4 is a protein that in humans is encoded by the TMTC4 gene. This protein crosses the plasma membrane 10 times, and resides in the ER lumen and cytosol. The predicted structure of the TMTC4 protein is a series of alpha-helices.

TTC1 protein-coding gene in the species Homo sapiens

Tetratricopeptide repeat protein 1 is a protein that in humans is encoded by the TTC1 gene.

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TTC4 protein-coding gene in the species Homo sapiens

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TTC28 protein-coding gene in the species Homo sapiens

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Tetratricopeptide repeat and ankyrin repeat containing 1 is a protein that in humans is encoded by the TRANK1 gene.

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Sid1 transmembrane family member 2 protein-coding gene in the species Homo sapiens

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Leucine-rich repeats and death domain containing 1 is a protein that in humans is encoded by the LRRD1 gene.

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Leucine rich repeat and fibronectin type III domain containing 4 is a protein that in humans is encoded by the LRFN4 gene.

Tectonin beta-propeller repeat containing 1 protein-coding gene in the species Homo sapiens

Tectonin beta-propeller repeat containing 1 is a protein that in humans is encoded by the TECPR1 gene.

TMIGD1 protein-coding gene in the species Homo sapiens

Transmembrane and immunoglobulin domain containing 1 is a protein that in humans is encoded by the TMIGD1 gene.

P4HTM protein-coding gene in the species Homo sapiens

Prolyl 4-hydroxylase, transmembrane is a protein that in humans is encoded by the P4HTM gene.

CKLF like MARVEL transmembrane domain containing 6 protein-coding gene in the species Homo sapiens

CKLF like MARVEL transmembrane domain containing 6 is a protein that in humans is encoded by the CMTM6 gene.

Kelch repeat and btb domain containing 11 protein-coding gene in the species Homo sapiens

Kelch repeat and BTB domain containing 11 is a protein that in humans is encoded by the KBTBD11 gene.

Transmembrane 6 superfamily member 1 protein-coding gene in the species Homo sapiens

Transmembrane 6 superfamily member 1 is a protein that in humans is encoded by the TM6SF1 gene.

References

  1. 1 2 3 GRCh38: Ensembl release 89: ENSG00000133687 - Ensembl, May 2017
  2. 1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000030306 - Ensembl, May 2017
  3. ↑ "Human PubMed Reference:".
  4. ↑ "Mouse PubMed Reference:".
  5. ↑ "Entrez Gene: Transmembrane and tetratricopeptide repeat containing 1" . Retrieved 2016-03-21.

Further reading


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