 | |
| Discipline | Transplantation medicine |
|---|---|
| Language | English |
| Edited by | Barry D. Kahan |
| Publication details | |
| History | 1969-present |
| Publisher | |
| Frequency | 10/year |
| 1.066 (2020) | |
| Standard abbreviations | |
| ISO 4 | Transplant. Proc. |
| Indexing | |
| CODEN | TRPPA8 |
| ISSN | 0041-1345 (print) 1873-2623 (web) |
| OCLC no. | 01767705 |
| Links | |
Transplantation Proceedings is a peer-reviewed medical journal covering the field of organ transplantation. It is the official publication of 27 international societies in this field. [1]
Organ transplantation is a medical procedure in which an organ is removed from one body and placed in the body of a recipient, to replace a damaged or missing organ. The donor and recipient may be at the same location, or organs may be transported from a donor site to another location. Organs and/or tissues that are transplanted within the same person's body are called autografts. Transplants that are recently performed between two subjects of the same species are called allografts. Allografts can either be from a living or cadaveric source.
The pancreatic islets or islets of Langerhans are the regions of the pancreas that contain its endocrine (hormone-producing) cells, discovered in 1869 by German pathological anatomist Paul Langerhans. The pancreatic islets constitute 1–2% of the pancreas volume and receive 10–15% of its blood flow. The pancreatic islets are arranged in density routes throughout the human pancreas, and are important in the metabolism of glucose.
A nursery is a place where plants are propagated and grown to a desired size. In a word, a nursery is a centre of seedling production where seedlings are produced and taken care until transplantation in the main field. Mostly the plants concerned are for gardening, forestry, or conservation biology, rather than agriculture. They include retail nurseries, which sell to the general public; wholesale nurseries, which sell only to businesses such as other nurseries and commercial gardeners; and private nurseries, which supply the needs of institutions or private estates. Some will also work in plant breeding.
Sirolimus, also known as rapamycin and sold under the brand name Rapamune among others, is a macrolide compound that is used to coat coronary stents, prevent organ transplant rejection, treat a rare lung disease called lymphangioleiomyomatosis, and treat perivascular epithelioid cell tumor (PEComa). It has immunosuppressant functions in humans and is especially useful in preventing the rejection of kidney transplants. It is a mechanistic target of rapamycin kinase (mTOR) inhibitor that inhibits activation of T cells and B cells by reducing their sensitivity to interleukin-2 (IL-2).
Transplant rejection occurs when transplanted tissue is rejected by the recipient's immune system, which destroys the transplanted tissue. Transplant rejection can be lessened by determining the molecular similitude between donor and recipient and by use of immunosuppressant drugs after transplant.
Xenotransplantation, or heterologous transplant, is the transplantation of living cells, tissues or organs from one species to another. Such cells, tissues or organs are called xenografts or xenotransplants. It is contrasted with allotransplantation, syngeneic transplantation or isotransplantation and autotransplantation. Xenotransplantation is an artificial method of creating an animal-human chimera, that is, a human with a subset of animal cells. In contrast, an individual where each cell contains genetic material from a human and an animal is called a human–animal hybrid.
King Edward Memorial Hospital and Seth Gordhandas Sunderdas Medical College is one of the foremost medical colleges and hospital in India, located in Mumbai, Maharashtra. It was founded in 1926; it is affiliated with Maharashtra University of Health Sciences (MUHS).
Thomas Earl Starzl was an American physician, researcher, and expert on organ transplants. He performed the first human liver transplants, and has often been referred to as "the father of modern transplantation." A documentary, entitled "Burden of Genius," covering the medical and scientific advances spearheaded by Starzl himself, was released to the public in 2017 in a series of screenings. Dr. Starzl also penned his autobiography, "The Puzzle People: Memoirs Of A Transplant Surgeon," which was published in 1992.
Open access citation advantage (OACA), sometimes known as FUTON bias, is a type of bias whereby scholars tend to cite academic journals with open access (OA)—that is, journals that make their full text available on the Internet without charge —in preference to toll-access publications. The concept was introduced, under the FUTON bias name, by UK medical researcher Reinhard Wentz in a letter to The Lancet in 2002.
Vladimir Petrovich Demikhov was a Soviet scientist and organ transplantation pioneer, who performed several transplants in the 1940s and 1950s, including the transplantation of a heart into an animal and a heart–lung replacement in an animal. He is also well known for his dog head transplants, which he conducted during the 1950s, resulting in two-headed dogs. This ultimately led to the head transplants in monkeys by Dr. Robert White, who was inspired by Demikhov's work.
Odulimomab is an investigational drug for the prevention of transplant rejection and for the treatment of various immunological diseases.
Forkhead box protein H1 is a protein that in humans is encoded by the FOXH1 gene.
A heart transplant, or a cardiac transplant, is a surgical transplant procedure performed on patients with end-stage heart failure or severe coronary artery disease when other medical or surgical treatments have failed. As of 2018, the most common procedure is to take a functioning heart, with or without both lungs, from a recently deceased organ donor and implant it into the patient. The patient's own heart is either removed and replaced with the donor heart or, much less commonly, the recipient's diseased heart is left in place to support the donor heart.
The Madras Institute of Orthopaedics and Traumatology, known in short as the MIOT International Hospital, is a multi-specialty hospital in Manapakkam, Chennai, India. It is a specialty hospital in the field of joint replacement surgeries, Interventional Cardiology, orthopaedics and trauma. Founded by P. V. A. Mohandas, the hospital was established in February 1999 on a 14-acre (5.7 ha) land with German collaboration, with an initial investment of ₹500,000. The hospital has 1000 beds and employs 170 physicians. It receives nearly 3,500 foreign patients every year, contributing 25 percent of the hospital's patients. North and East Africa account for many of these foreign patients.
Sunil Shroff is the managing trustee of a non-government and non-profit organisation called MOHAN Foundation and is well known for his work in the field of deceased donation transplantation in India. He has worked towards improving the deceased organ donation rate in India.
Hargovind Laxmishanker "H. L." Trivedi was an Indian nephrologist, immunologist, transplant surgeon and stem cell researcher.
Atrimustine (INN), also known as bestrabucil or busramustine, is a cytostatic antineoplastic agent which was under development in Japan by Kureha Chemicals for the treatment of breast cancer and non-Hodgkin's lymphoma as well as for the prevention of graft-versus-host disease in bone marrow transplant recipients. It is the benzoate ester of an ester conjugate of estradiol and chlorambucil, which results in targeted/site-directed cytostatic activity toward estrogen receptor-positive tissues such as breast and bone. It reached preregistration for the treatment of cancer but was ultimately discontinued. Estrogenicic side effects of atrimustine in clinical trials included vaginal bleeding and gynecomastia. The drug was first patented in 1980.
The World Transplant Games (WTG) are an international multi-sport event, occurring every two years, organized by the World Transplant Games Federation (WTGF). The Games promote amateur sport amongst organ transplant recipients, living donors and donor families.
Mammen Chandy is a former director of Tata Medical Center, Kolkata. Chandy, an alumnus of Christian Medical College Vellore, is a pioneer in the field of bone marrow transplantation in India. He was involved in setting up the first bone marrow transplantation program in the country at Christian Medical College, Vellore in 1986. In January 2019, Chandy was awarded Padma Shri for his contribution to the field of medicine in 2019.
Richard C. Lillehei was an American transplant surgeon best remembered for the world's first successful simultaneous pancreas-kidney transplant in 1966 and the first known human intestinal transplantation. He came from a renowned medical family in Minneapolis; his father was a dentist and his brothers were cardiologist James Lillehei and cardiothoracic surgeon C. Walton Lillehei. The Lillehei Surgical Society is named in honour of the three brothers.
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