Wen, wen, or WEN may refer to:
- One of several Chinese surnames:
- Wen, alternate spelling for Wynn (Ƿ ƿ), a letter of the Old English alphabet
- Wen, common name for trichilemmal cyst or pilar cyst
- Wen, sebaceous cyst, a form of trichilemmal cyst
- Wen, alternate name for lipoma, a benign tumor composed of adipose tissue
- wen, the ISO 639-2 code for the Sorbian languages, also known as Wendish languages
- WEN, New York Stock Exchange symbol for Wendy's/Arby's Group
- WEN, Amtrak station code for Columbia Station in Wenatchee, Washington, United States
- WEN, ICAO airline designator for WestJet Encore
- Chinese wen or wén, a coin or currency-unit in the monetary system of Imperial China
