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Cosmic rays or astroparticles are high-energy particles or clusters of particles that move through space at nearly the speed of light. They originate from the Sun, from outside of the Solar System in our own galaxy, and from distant galaxies. Upon impact with Earth's atmosphere, cosmic rays produce showers of secondary particles, some of which reach the surface, although the bulk are deflected off into space by the magnetosphere or the heliosphere.
Chronobiology is a field of biology that examines timing processes, including periodic (cyclic) phenomena in living organisms, such as their adaptation to solar- and lunar-related rhythms. These cycles are known as biological rhythms. Chronobiology comes from the ancient Greek χρόνος, and biology, which pertains to the study, or science, of life. The related terms chronomics and chronome have been used in some cases to describe either the molecular mechanisms involved in chronobiological phenomena or the more quantitative aspects of chronobiology, particularly where comparison of cycles between organisms is required.
The year 1999 in science and technology involved some significant events.
Bacteriorhodopsin (Bop) is a protein used by Archaea, most notably by haloarchaea, a class of the Euryarchaeota. It acts as a proton pump; that is, it captures light energy and uses it to move protons across the membrane out of the cell. The resulting proton gradient is subsequently converted into chemical energy.
Retinal is a polyene chromophore. Retinal, bound to proteins called opsins, is the chemical basis of visual phototransduction, the light-detection stage of visual perception (vision).
Melanopsin is a type of photopigment belonging to a larger family of light-sensitive retinal proteins called opsins and encoded by the gene Opn4. In the mammalian retina, there are two additional categories of opsins, both involved in the formation of visual images: rhodopsin and photopsin in the rod and cone photoreceptor cells, respectively.
Proteorhodopsin is a family of transmembrane proteins that use retinal as a chromophore for light-mediated functionality, in this case, a proton pump. pRhodopsin is found in marine planktonic bacteria, archaea and eukaryotes (protae), but was first discovered in bacteria.
Horizontal cells are the laterally interconnecting neurons having cell bodies in the inner nuclear layer of the retina of vertebrate eyes. They help integrate and regulate the input from multiple photoreceptor cells. Among their functions, horizontal cells are believed to be responsible for increasing contrast via lateral inhibition and adapting both to bright and dim light conditions. Horizontal cells provide inhibitory feedback to rod and cone photoreceptors. They are thought to be important for the antagonistic center-surround property of the receptive fields of many types of retinal ganglion cells.
Intrinsically photosensitive retinal ganglion cells (ipRGCs), also called photosensitive retinal ganglion cells (pRGC), or melanopsin-containing retinal ganglion cells (mRGCs), are a type of neuron in the retina of the mammalian eye. The presence of something like ipRGCs was first suspected in 1927 when rodless, coneless mice still responded to a light stimulus through pupil constriction; this implied that rods and cones are not the only light-sensitive neurons in the retina. Yet research on these cells did not advance until the 1980s. Recent research has shown that these retinal ganglion cells, unlike other retinal ganglion cells, are intrinsically photosensitive due to the presence of melanopsin, a light-sensitive protein. Therefore, they constitute a third class of photoreceptors, in addition to rod and cone cells.
A retinal implant is a visual prosthesis for restoration of sight to patients blinded by retinal degeneration. The system is meant to partially restore useful vision to those who have lost their photoreceptors due to retinal diseases such as retinitis pigmentosa (RP) or age-related macular degeneration (AMD). Retinal implants are being developed by a number of private companies and research institutions, and three types are in clinical trials: epiretinal, subretinal, and suprachoroidal. The implants introduce visual information into the retina by electrically stimulating the surviving retinal neurons. So far, elicited percepts had rather low resolution, and may be suitable for light perception and recognition of simple objects.
The Tolman–Oppenheimer–Volkoff limit is an upper bound to the mass of cold, non-rotating neutron stars, analogous to the Chandrasekhar limit for white dwarf stars. Stars more massive than the TOV limit collapse into a black hole. The original calculation in 1939, which neglected complications such as nuclear forces between neutrons, placed this limit at approximately 0.7 solar masses (M☉). Later, more refined analyses have resulted in larger values.
Eridania Lake is a theorized ancient lake on Mars with a surface area of roughly 1.1 million square kilometers. It is located at the source of the Ma'adim Vallis outflow channel and extends into Eridania quadrangle and the Phaethontis quadrangle. As Eridania Lake dried out in the late Noachian epoch it divided into a series of smaller lakes.
Ignacio Provencio is an American neuroscientist and the discoverer of melanopsin, an opsin found in specialized photosensitive ganglion cells of the mammalian retina. Provencio served as the program committee chair of the Society for Research on Biological Rhythms from 2008 to 2010.
Health threats from cosmic rays are the dangers posed by cosmic rays to astronauts on interplanetary missions or any missions that venture through the Van-Allen Belts or outside the Earth's magnetosphere. They are one of the greatest barriers standing in the way of plans for interplanetary travel by crewed spacecraft, but space radiation health risks also occur for missions in low Earth orbit such as the International Space Station (ISS).
Almost all water on Mars today exists as ice, though it also exists in small quantities as vapor in the atmosphere. What was thought to be low-volume liquid brines in shallow Martian soil, also called recurrent slope lineae, may be grains of flowing sand and dust slipping downhill to make dark streaks. While most water ice is buried, it is exposed at the surface across several locations on Mars. In the mid-latitudes, it is exposed by impact craters, steep scarps and gullies. Additionally, water ice is also visible at the surface at the north polar ice cap. Abundant water ice is also present beneath the permanent carbon dioxide ice cap at the Martian south pole. More than 5 million km3 of ice have been detected at or near the surface of Mars, enough to cover the whole planet to a depth of 35 meters (115 ft). Even more ice might be locked away in the deep subsurface. Some liquid water may occur transiently on the Martian surface today, but limited to traces of dissolved moisture from the atmosphere and thin films, which are challenging environments for known life. No evidence of present-day liquid water has been discovered on the planet's surface because under typical Martian conditions, warming water ice on the Martian surface would sublime at rates of up to 4 meters per year. Before about 3.8 billion years ago, Mars may have had a denser atmosphere and higher surface temperatures, potentially allowing greater amounts of liquid water on the surface, possibly including a large ocean that may have covered one-third of the planet. Water has also apparently flowed across the surface for short periods at various intervals more recently in Mars' history. Aeolis Palus in Gale Crater, explored by the Curiosity rover, is the geological remains of an ancient freshwater lake that could have been a hospitable environment for microbial life. The present-day inventory of water on Mars can be estimated from spacecraft images, remote sensing techniques, and surface investigations from landers and rovers. Geologic evidence of past water includes enormous outflow channels carved by floods, ancient river valley networks, deltas, and lakebeds; and the detection of rocks and minerals on the surface that could only have formed in liquid water. Numerous geomorphic features suggest the presence of ground ice (permafrost) and the movement of ice in glaciers, both in the recent past and present. Gullies and slope lineae along cliffs and crater walls suggest that flowing water continues to shape the surface of Mars, although to a far lesser degree than in the ancient past.
Russell Grant Foster, CBE, FRS FMedSci is a British professor of circadian neuroscience, the Director of the Nuffield Laboratory of Ophthalmology and the Head of the Sleep and Circadian Neuroscience Institute (SCNi). He is also a Nicholas Kurti Senior Fellow at Brasenose College at the University of Oxford. Foster and his group are credited with key contributions to the discovery of the non-rod, non-cone, photosensitive retinal ganglion cells (pRGCs) in the mammalian retina which provide input to the circadian rhythm system. He has written and co-authored over a hundred scientific publications.
A planetary surface is where the solid or liquid material of certain types of astronomical objects contacts the atmosphere or outer space. Planetary surfaces are found on solid objects of planetary mass, including terrestrial planets, dwarf planets, natural satellites, planetesimals and many other small Solar System bodies (SSSBs). The study of planetary surfaces is a field of planetary geology known as surface geology, but also a focus on a number of fields including planetary cartography, topography, geomorphology, atmospheric sciences, and astronomy. Land is the term given to non-liquid planetary surfaces. The term landing is used to describe the collision of an object with a planetary surface and is usually at a velocity in which the object can remain intact and remain attached.
King-Wai Yau is a Chinese-born American neuroscientist and Professor of Neuroscience at Johns Hopkins University School of Medicine in Baltimore, Maryland.
Microbial rhodopsins, also known as bacterial rhodopsins, are retinal-binding proteins that provide light-dependent ion transport and sensory functions in halophilic and other bacteria. They are integral membrane proteins with seven transmembrane helices, the last of which contains the attachment point for retinal. Most microbial rhodopsins pump inwards, however "mirror rhodopsins" which function outwards. have been discovered.
References
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