Descinolone

Last updated
Descinolone
Descinolone.svg
Clinical data
Synonyms Desoxytriamcinolone; 21-Desoxytriamcinolone; 9α-Fluoro-11β,16α,17α-trihydroxypregna-1,4-diene-3,20-dione
Drug class Corticosteroid; Glucocorticoid
Identifiers
CAS Number
PubChem CID
ChemSpider
UNII
KEGG
ChEBI
ChEMBL
Chemical and physical data
Formula C21H27FO5
Molar mass 378.44 g·mol−1
3D model (JSmol)

Descinolone is a synthetic glucocorticoid corticosteroid which was never marketed. [1]

Glucocorticoid class of corticosteroids

Glucocorticoids are a class of corticosteroids, which are a class of steroid hormones. Glucocorticoids are corticosteroids that bind to the glucocorticoid receptor that is present in almost every vertebrate animal cell. The name "glucocorticoid" is a portmanteau and is composed from its role in regulation of glucose metabolism, synthesis in the adrenal cortex, and its steroidal structure. A less common synonym is glucocorticosteroid.

Corticosteroid steroid hormone

Corticosteroids are a class of steroid hormones that are produced in the adrenal cortex of vertebrates, as well as the synthetic analogues of these hormones. Two main classes of corticosteroids, glucocorticoids and mineralocorticoids, are involved in a wide range of physiological processes, including stress response, immune response, and regulation of inflammation, carbohydrate metabolism, protein catabolism, blood electrolyte levels, and behavior.

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Safety data sheet System for cataloging information, potential hazards and instructions for safe use associated with a material or product

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KEGG biological database

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ChemSpider database of chemicals owned by the Royal Society of Chemistry; see P661

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Canrenoic acid

Canrenoic acid is a synthetic steroidal antimineralocorticoid which was never marketed.

Riodipine chemical compound

Riodipine (INN) is a calcium channel blocker.

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Gestaclone chemical compound

Gestaclone, also known as 6-chloro-1α,2α:16α,17-bismethylene-4,6-pregnadiene-3,20-dione, is a steroidal progestin of unique chemical structure derived from progesterone that was first described in 1967 and was never marketed.

Leptacline chemical compound

Leptacline (INN) is a drug described as a respiratory stimulant that was never marketed. It has a similar chemical structure to various piperidine and piperazine psychostimulants.

Idropranolol chemical compound

Idropranolol is a beta blocker that was never marketed.

Doisynoestrol

Doisynoestrol, also known as fenocycline, as well as cis-bisdehydrodoisynolic acid 7-methyl ether, is a synthetic nonsteroidal estrogen of the doisynolic acid group that is no longer marketed. It is a methyl ether of bisdehydrodoisynolic acid. Doisynoestrol was described in the literature in 1945.

Pentomone

Pentomone is a nonsteroidal antiandrogen (NSAA) described as a "prostate growth inhibitor" which was never marketed. It was synthesized and assayed in 1978.

Furostilbestrol

Furostilbestrol (INN), also known as diethylstilbestrol di(2-furoate) or simply as diesthylstilbestrol difuroate, is a synthetic, nonsteroidal estrogen of the stilbestrol group related to diethylstilbestrol that was never marketed. It is an ester of diethylstilbestrol and was described in the literature in 1952.

Clomifenoxide chemical compound

Clomifenoxide (INN), also known as clomifene N-oxide, is a nonsteroidal selective estrogen receptor modulator (SERM) of the triphenylethylene group that is described as an antiestrogen and "gonad stimulant" and was never marketed. It is an active metabolite of clomifene.

Nitromifene chemical compound

Nitromifene is a nonsteroidal selective estrogen receptor modulator (SERM) related to triphenylethylenes like tamoxifen that was never marketed. It is a mixture of (E)- and (Z)-isomers that possess similar antiestrogenic activity. The drug was described in 1966. Along with tamoxifen, nafoxidine, and clomifene, it was one of the earliest SERMs.

Timobesone chemical compound

Timobesone is a synthetic glucocorticoid corticosteroid which was never marketed.

References

  1. J. Elks (14 November 2014). The Dictionary of Drugs: Chemical Data: Chemical Data, Structures and Bibliographies. Springer. pp. 362–. ISBN   978-1-4757-2085-3.