Exocrine gland

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Exocrine gland
Centroacinar cells.jpg
An acinus is a round cluster of exocrine cells connected to a duct.
Details
Identifiers
Latin glandula exocrina
MeSH D005088
TH H2.00.02.0.03014
FMA 9596
Anatomical terminology

Exocrine glands are glands that secrete substances onto an epithelial surface by way of a duct. [1] Examples of exocrine glands include sweat, salivary, mammary, ceruminous, lacrimal, sebaceous, prostate and mucous. Exocrine glands are one of two types of glands in the human body, the other being endocrine glands, which secrete their products directly into the bloodstream. The liver and pancreas are both exocrine and endocrine glands; they are exocrine glands because they secrete products—bile and pancreatic juice—into the gastrointestinal tract through a series of ducts, and endocrine because they secrete other substances directly into the bloodstream. Exocrine sweat glands are part of the integumentary system; they have eccrine and apocrine types.

Contents

Classification

Structure

Exocrine glands contain a glandular portion and a duct portion, the structures of which can be used to classify the gland. [1]

Method of secretion

Depending on how their products are secreted, exocrine glands are categorized as merocrine, apocrine, or holocrine. [1]

Product secreted

Additional images

See also

Related Research Articles

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In animals, a gland is a group of cells in an animal's body that synthesizes substances for release into the bloodstream or into cavities inside the body or its outer surface.

<span class="mw-page-title-main">Saliva</span> Bodily fluid secreted by salivary glands

Saliva is an extracellular fluid produced and secreted by salivary glands in the mouth. In humans, saliva is around 99% water, plus electrolytes, mucus, white blood cells, epithelial cells, enzymes, antimicrobial agents.

<span class="mw-page-title-main">Salivary gland</span> Exocrine glands that produce saliva through a system of ducts

The salivary glands in many vertebrates including mammals are exocrine glands that produce saliva through a system of ducts. Humans have three paired major salivary glands, as well as hundreds of minor salivary glands. Salivary glands can be classified as serous, mucous, or seromucous (mixed).

<span class="mw-page-title-main">Sebaceous gland</span> Gland to lubricate the hair and skin

A sebaceous gland or oil gland is a microscopic exocrine gland in the skin that opens into a hair follicle to secrete an oily or waxy matter, called sebum, which lubricates the hair and skin of mammals. In humans, sebaceous glands occur in the greatest number on the face and scalp, but also on all parts of the skin except the palms of the hands and soles of the feet. In the eyelids, meibomian glands, also called tarsal glands, are a type of sebaceous gland that secrete a special type of sebum into tears. Surrounding the female nipple, areolar glands are specialized sebaceous glands for lubricating the nipple. Fordyce spots are benign, visible, sebaceous glands found usually on the lips, gums and inner cheeks, and genitals.

<span class="mw-page-title-main">Apocrine</span> Classification of secretion of exocrine glands

Apocrine is a term used to classify the mode of secretion of exocrine glands. In apocrine secretion, secretory cells accumulate material at their apical ends, often forming blebs or "snouts", and this material then buds off from the cells, forming extracellular vesicles. The secretory cells therefore lose part of their cytoplasm in the process of secretion.

<span class="mw-page-title-main">Submandibular gland</span> Human salivary gland

The paired submandibular glands are major salivary glands located beneath the floor of the mouth. In adult humans, they each weigh about 15 grams and contribute some 60–67% of unstimulated saliva secretion; on stimulation their contribution decreases in proportion as parotid gland secretion rises to 50%. The average length of the normal adult human submandibular salivary gland is approximately 27 mm, while the average width is approximately 14.3 mm.

<span class="mw-page-title-main">Digestive enzyme</span> Class of enzymes

Digestive enzymes are a group of enzymes that break down polymeric macromolecules into their smaller building blocks, in order to facilitate their absorption into the cells of the body. Digestive enzymes are found in the digestive tracts of animals and in the tracts of carnivorous plants, where they aid in the digestion of food, as well as inside cells, especially in their lysosomes, where they function to maintain cellular survival. Digestive enzymes of diverse specificities are found in the saliva secreted by the salivary glands, in the secretions of cells lining the stomach, in the pancreatic juice secreted by pancreatic exocrine cells, and in the secretions of cells lining the small and large intestines.

<span class="mw-page-title-main">Sweat gland</span> Small sweat-producing tubular skin structures

Sweat glands, also known as sudoriferous or sudoriparous glands, from Latin sudor 'sweat', are small tubular structures of the skin that produce sweat. Sweat glands are a type of exocrine gland, which are glands that produce and secrete substances onto an epithelial surface by way of a duct. There are two main types of sweat glands that differ in their structure, function, secretory product, mechanism of excretion, anatomic distribution, and distribution across species:

In physiology, serous fluid or serosal fluid is any of various body fluids resembling serum, that are typically pale yellow or transparent and of a benign nature. The fluid fills the inside of body cavities. Serous fluid originates from serous glands, with secretions enriched with proteins and water. Serous fluid may also originate from mixed glands, which contain both mucous and serous cells. A common trait of serous fluids is their role in assisting digestion, excretion, and respiration.

<span class="mw-page-title-main">Holocrine</span> Term used to classify the mode of secretion in exocrine glands in the study of histology

Holocrine is a term used to classify the mode of secretion in exocrine glands in the study of histology. Holocrine secretions are produced in the cytoplasm of the cell and released by the rupture of the plasma membrane, which destroys the cell and results in the secretion of the product into the lumen.

<span class="mw-page-title-main">Merocrine</span> Secretory mechanism

Merocrine is a term used to classify exocrine glands and their secretions in the study of histology. A cell is classified as merocrine if the secretions of that cell are excreted via exocytosis from secretory cells into an epithelial-walled duct or ducts and then onto a bodily surface or into the lumen.

<span class="mw-page-title-main">Acinus</span> Multi-lobed biological cell structure

An acinus refers to any cluster of cells that resembles a many-lobed "berry," such as a raspberry. The berry-shaped termination of an exocrine gland, where the secretion is produced, is acinar in form, as is the alveolar sac containing multiple alveoli in the lungs.

<span class="mw-page-title-main">Duct (anatomy)</span>

In anatomy and physiology, a duct is a circumscribed channel leading from an exocrine gland or organ.

An apocrine sweat gland is composed of a coiled secretory portion located at the junction of the dermis and subcutaneous fat, from which a straight portion inserts and secretes into the infundibular portion of the hair follicle. In humans, apocrine sweat glands are found only in certain locations of the body: the axillae (armpits), areola and nipples of the breast, ear canal, eyelids, wings of the nostril, perineal region, and some parts of the external genitalia. Modified apocrine glands include the ciliary glands in the eyelids; the ceruminous glands, which produce ear wax; and the mammary glands, which produce milk. They are distinct from eccrine sweat glands which cover the whole body.

<span class="mw-page-title-main">Eccrine sweat gland</span> Sweat gland distributed almost all over the human body

Eccrine sweat glands are the major sweat glands of the human body. Eccrine sweat glands are found in virtually all skin, with the highest density in the palms of the hands, and soles of the feet, and on the head, but much less on the torso and the extremities. In other mammals, they are relatively sparse, being found mainly on hairless areas such as foot pads. They reach their peak of development in humans, where they may number 200–400/cm2 of skin surface. They produce sweat, a merocrine secretion which is clear, odorless substance, consisting primarily of water. These are present from birth. Their secretory part is present deep inside the dermis.

<span class="mw-page-title-main">Mucous gland</span>

Mucous gland, also known as muciparous glands, are found in several different parts of the body, and they typically stain lighter than serous glands during standard histological preparation. Most are multicellular, but goblet cells are single-celled glands.

Skin appendages are anatomical skin-associated structures that serve a particular function including sensation, contractility, lubrication and heat loss in animals. In humans, some of the more common skin appendages are hairs, arrector pilli, sebaceous glands, sweat glands (can secrete sweat with strong odour or with a faint odour, and nails.

<span class="mw-page-title-main">Human digestive system</span> Digestive system in humans

The human digestive system consists of the gastrointestinal tract plus the accessory organs of digestion. Digestion involves the breakdown of food into smaller and smaller components, until they can be absorbed and assimilated into the body. The process of digestion has three stages: the cephalic phase, the gastric phase, and the intestinal phase.

Heterocrine glands are the glands which function as both exocrine gland and endocrine gland. These glands exhibit a unique and diverse secretory function encompassing the release of proteins and non-proteinaceous compounds, endocrine and exocrine secretions into both the bloodstream and ducts respectively, thereby bridging the realms of internal and external communication within the body. This duality allows them to serve crucial roles in regulating various physiological processes and maintaining homeostasis. These include the gonads, pancreas and salivary glands.

References

  1. 1 2 3 Young, Barbara; O'Dowd, Geraldine; Woodford, Phillip (2013). Wheater's Functional Histology: A Text and Colour Atlas (Sixth ed.). Elsevier. p. 95. ISBN   978-0702047473. LCCN   2013036824.