Interstate 72 (I-72) is an Interstate Highway in the midwestern United States. Its western terminus is in Hannibal, Missouri, at an intersection with U.S. Route 61 (US 61); its eastern terminus is at Country Fair Drive in Champaign, Illinois. The route runs through the major cities of Decatur, Illinois, and Springfield, Illinois. In 2006, the Illinois General Assembly dedicated all of I-72 as Purple Heart Memorial Highway. The stretch between Springfield and Decatur is also called Penny Severns Memorial Expressway, and the section between mile 35 and the Mississippi River is known as the Free Frank McWorter Historic Highway.
U.S. Route 61 or U.S. Highway 61 (U.S. 61) is a major United States highway that extends 1,400 miles (2,300 km) between New Orleans, Louisiana and the city of Wyoming, Minnesota. The highway generally follows the course of the Mississippi River and is designated the Great River Road for much of its route. As of 2004, the highway's northern terminus in Wyoming, Minnesota, is at an intersection with Interstate 35 (I-35). Until 1991, the highway extended north on what is now Minnesota State Highway 61 through Duluth to the Canada–U.S. border near Grand Portage. Its southern terminus in New Orleans is at an intersection with U.S. Route 90. The route was an important south–north connection in the days before the interstate highway system.
U.S. Route 79 is a United States highway in the Southern United States. The route is officially considered and labeled as a north-south highway, but its path is actually more of a diagonal northeast-southwest highway. The highway's northern/eastern terminus is in Russellville, Kentucky, at an intersection with U.S. Route 68 and KY 80. Its southern/western terminus is in Round Rock, Texas, at an interchange with Interstate 35, ten miles (16 km) north of Austin. US 79, US 68, and Interstate 24/US 62 are the primary east–west access points for the Land Between the Lakes recreation area straddling the Kentucky/Tennessee border.
U.S. Route 2 or U.S. Highway 2 (US 2) is an east–west United States Numbered Highway spanning 2,571 miles (4,138 km) across the northern continental United States. US 2 consists of two segments connected by various roadways in southern Canada. Unlike some routes, which are disconnected into segments because of encroaching Interstate Highways, the two portions of US 2 were designed to be separate in the original 1926 highway plan.
U.S. Route 71 or U.S. Highway 71 is a major north–south United States highway that extends for over 1500 miles (2500 km) in the central United States. This original 1926 route has remained largely unchanged by encroaching Interstate highways. Currently, the highway's northern terminus is in International Falls, Minnesota at the Canada–US border, at the southern end of the Fort Frances-International Falls International Bridge to Fort Frances, Ontario. U.S. Route 53 also ends here. On the other side of the bridge, Trans-Canada Highway is an east–west route while Ontario Highway 71 is a north–south route. US 71's southern terminus is between Port Barre and Krotz Springs, Louisiana at an intersection with U.S. Route 190. For the entirety south of Kansas City, Missouri, US 71 runs parallel and concurrent with the existing and future Interstate 49. North of Kansas City, US 71 runs halfway between Interstate 29 and Interstate 35, which they split in the city at an interchange with Interstate 70.
U.S. Route 183 (US 183) is a north–south United States highway. The highway's northern terminus is in Presho, South Dakota, at an intersection with Interstate 90. Its southern terminus is in Refugio, Texas, at the southern intersection of U.S. Highway 77 and Alternate US 77.
U.S. Route 65 is a north–south United States highway in the southern and midwestern United States. The southern terminus of the route is at U.S. Route 425 in Clayton, Louisiana. The northern terminus is at Interstate 35 just south of Interstate 90 in Albert Lea, Minnesota. Parts of its modern route in Iowa and historic route in Minnesota follow the old Jefferson Highway.
U.S. Route 36 (US 36) is an east–west United States highway that travels approximately 1,414 miles (2,276 km) from Rocky Mountain National Park, Colorado to Uhrichsville, Ohio. The highway's western terminus is at Deer Ridge Junction, an intersection in Rocky Mountain National Park, Colorado, where it meets US 34. Its eastern terminus is at US 250 in Uhrichsville, Ohio.
U.S. Route 54 is an east–west United States Highway that runs northeast–southwest for 1,197 miles (1,926 km) from El Paso, Texas, to Griggsville, Illinois. The Union Pacific Railroad's Tucumcari Line runs parallel to US 54 from El Paso to Pratt, Kansas, which comprises about two-thirds of the route.
New Hampshire Route 12 is a 62.773-mile (101.023 km) long north-south state highway in southwestern New Hampshire. Its southern terminus is at the Massachusetts state line in Fitzwilliam, where it continues south as Massachusetts Route 12. Its northern terminus is at the Vermont state line in Claremont, where it continues north as Vermont Route 12. Most of the northern part of NH 12 runs along the Connecticut River.
Route 14 is a state highway traveling through the southern part of the U.S. state of Missouri. Its western terminus is at U.S. Route 60 (US 60) in Marionville, and its eastern terminus is at US 63 on the northern edge of West Plains. Route 14 is a two-lane highway for its entire length, however, there are plans to widen Route 14 in some spots.
Route 13 is a highway in Missouri which runs almost the entire north–south length of the state. Its northern terminus is at U.S. Route 69/136 in Bethany. Its southern terminus is at the Arkansas state line in downtown Blue Eye, Missouri–Arkansas where it continues as Highway 21. It is one of the original state highways of Missouri.
Route 76 is a highway in the west half of southern Missouri running between U.S. Route 60 and U.S. Route 63 at Willow Springs and the Oklahoma state line near Tiff City where it continues as a county road. It bypasses Branson on the Ozark Mountain High Road and is the namesake of the Branson strip, 76 Country Blvd. The road runs for its entirety through the Missouri Ozarks, and is at times very hilly and curvy.
Route 39 is a two-lane highway in southwestern Missouri. Its northern terminus is at U.S. Route 54 between Collins and El Dorado Springs at the community of Cedar Springs; its southern terminus is at the Arkansas state line where it continues as Highway 221.
Route 30 is a highway in eastern Missouri, United States. Its eastern terminus is at the Interstate 55/Interstate 44 junction in St. Louis. Its western terminus is at Interstate 44 in St. Clair. In St. Louis, the section between Interstate 44 and Route 366 is part of historic U.S. Route 66 and is marked as such. In the St. Louis area, it is known as Gravois Avenue or Gravois Road. Further south, Gravois Rd is used to mark the old section of the highway where the newer, divided highway rerouted Highway 30.
Route 19 is a long state highway in Missouri. Its northern terminus is at U.S. Route 61 in New London and its southern terminus is at U.S. Route 63 on the north side of Thayer. Route 19 is one of Missouri's original 1922 highways, though it initially had a northern terminus at Route 14 in Cuba and was later extended north.
Route 8 is a 69-mile-long (111 km) state highway in the eastern part of the U.S. state of Missouri. It travels from Interstate 44 (I-44) in St. James to U.S. Route 67 (US 67) and US 67 Business in Desloge. It acts as a bypass, from I-44 in St. James, to US 67 in Desloge. Travelers on I-44 can use it to avoid the traffic problems in St. Louis, to US 67 in Desloge, & vice versa. Those who want to go to Ste. Genevieve can take US 67 Bus. through Park Hills to US 67, to Farmington, then take Route 32 to Ste. Genevieve. There have supposedly been plans to extend Route 8 to Ste. Genevieve. So far, those plans have not been put into effect.
State Route 54 (SR 54) is a 70.5-mile-long (113.5 km) state highway that travels southwest-to-northeast through portions of Troup, Meriwether, Coweta, Fayette, Clayton, and Fulton counties in the northwestern part of the U.S. state of Georgia. The highway connects Hogansville with Atlanta, via Peachtree City, Fayetteville, Jonesboro, and Forest Park.
Interstate 44 (I-44) in the US state of Missouri runs northeast from the Oklahoma state line near Joplin to I-70 in Downtown St. Louis. It runs for about 293 miles (472 km) in the state, and is the longest Interstate Highway in the state.
U.S. Route 63 is the portion of a north-south highway that runs through the U.S. state of Missouri from the Arkansas state line near Thayer to the Iowa state line near Lancaster.
US 54 in El Dorado Springs 
