P2X purinoceptor 5 is a protein that in humans is encoded by the P2RX5 gene. [5] [6]
The product of this gene belongs to the family of purinoceptors for ATP. This receptor functions as a ligand-gated ion channel. Several characteristic motifs of ATP-gated channels are present in its primary structure, but, unlike other members of the purinoceptors family, this receptor has only a single transmembrane domain. Four transcript variants encoding distinct isoforms have been identified for this gene. [6]
ATP-binding cassette sub-family A member 12 also known as ATP-binding cassette transporter 12 is a protein that in humans is encoded by the ABCA12 gene.
P2Y12 is a chemoreceptor for adenosine diphosphate (ADP) that belongs to the Gi class of a group of G protein-coupled (GPCR) purinergic receptors. This P2Y receptor family has several receptor subtypes with different pharmacological selectivity, which overlaps in some cases, for various adenosine and uridine nucleotides. The P2Y12 receptor is involved in platelet aggregation and is thus a biological target for the treatment of thromboembolisms and other clotting disorders. Two transcript variants encoding the same isoform have been identified for this gene.
P2X purinoceptor 7 is a protein that in humans is encoded by the P2RX7 gene.
P2Y purinoceptor 1 is a protein that in humans is encoded by the P2RY1 gene.
P2X purinoceptor 1 is a protein that in humans is encoded by the P2RX1 gene.
P2Y purinoceptor 2 is a protein that in humans is encoded by the P2RY2 gene.
P2Y purinoceptor 11 is a protein that in humans is encoded by the P2RY11 gene.
P2Y purinoceptor 14 is a protein that in humans is encoded by the P2RY14 gene.
Lysophosphatidic acid receptor 6, also known as LPA6, P2RY5 and GPR87, is a protein that in humans is encoded by the LPAR6 gene. LPA6 is a G protein-coupled receptor that binds the lipid signaling molecule lysophosphatidic acid (LPA).
Putative P2Y purinoceptor 10 is a protein that, in humans, is encoded by the P2RY10 gene.
P2Y purinoceptor 13 is a protein that in humans is encoded by the P2RY13 gene.
P2Y purinoceptor 8 is a protein that in humans is encoded by the P2RY8 gene.
P2Y purinoceptor 4 is a protein that in humans is encoded by the P2RY4 gene.
HR is a gene encoding Protein hairless.
P2X purinoceptor 4 is a protein that in humans is encoded by the P2RX4 gene. The product of this gene belongs to the family of purinoceptors for ATP. Multiple alternatively spliced transcript variants have been identified for this gene although their full-length natures have not been determined.
P2X purinoceptor 2 is a protein that in humans is encoded by the P2RX2 gene.
P2X purinoceptor 3 is a protein that in humans is encoded by the P2RX3 gene.
Immunoglobulin superfamily member 8 is a protein that in humans is encoded by the IGSF8 gene. IGSF8 has also been designated as CD316.
Nuclear receptor-binding factor 2 is a protein that in humans is encoded by the NRBF2 gene.
P2X purinoceptor 6 is a protein that in humans is encoded by the P2RX6 gene.
This article incorporates text from the United States National Library of Medicine, which is in the public domain.