U.S. Route 431 (US 431) is a spur of U.S. Route 31. It currently travels for approximately 556 miles (895 km) from US 231/Alabama State Route 210 and US 231 Business and US 431 Bus. in Dothan, Alabama, to Owensboro, Kentucky, at US 60 and Kentucky Route 2831. The major cities US 431 connects to are Dothan and Huntsville, Alabama, Franklin and Nashville, Tennessee, and Owensboro, Kentucky.
State Route 2 is a 197-mile-long (317 km) west–to–east state highway in the U.S. state of Tennessee. It begins in Murfreesboro, in Rutherford County, and ends near Farragut in Loudon County. The route is both a primary and secondary route. Most of the route is unsigned.
State Route 22 is a 172.8-mile long (278.1 km) south-to-north state highway in the western part of Tennessee, United States. It begins at the Mississippi state line in McNairy County, where the roadway continues as Mississippi Highway 2. It ends at the Kentucky state line in Lake County, when it crosses into the Kentucky Bend, a detached portion of Fulton County, Kentucky. The monument for the 1862 Battle of Island Number Ten in the American Civil War is located on SR 22, about 3 mi (4.8 km) north of Tiptonville.
State Route 12 is a highway from Davidson County, Tennessee to Montgomery County, Tennessee.
State Route 96 is an east–west and north–south highway in Middle Tennessee. The road begins in Dickson and ends in Granville. The current length is 126.7 mi (203.9 km). Along its path it goes through 10 counties. Locals mostly refer to it as Highway 96.
State Route 99 is a long east–west highway in Middle Tennessee. The route travels through large sections of rural areas and for most of the length is a secondary highway. The route begins near Waynesboro and ends in Bradyville after logging 126.7 mi (203.9 km) and passing through six counties.
State Route 10 is a south–north route from the Alabama state line in Lincoln County to the Kentucky state line in Macon County.
State Route 13, in the United States, is a south–north route from the Alabama border in Wayne County to the Kentucky border in Montgomery County. The entire route is located in western Middle Tennessee.
State Route 15 is a west–east route from Memphis to Monteagle. For much of its route it has an unsigned concurrency with U.S. Route 64. SR 15 does travel through the southern part of all 3 Grand Divisions of the state: West Tennessee, Middle Tennessee, and East Tennessee.
State Route 76 (SR 76) is a state highway in Tennessee, traversing the state in a northeast-southwest axis from east of Memphis to north of Nashville. SR 76 is unique in that it actually changes its cardinal directions in Clarksville at the junction with US 41A and US 41A Bypass.
U.S. Route 41 (US 41) is a United States Numbered Highway that runs from Miami, Florida, to Copper Harbor, Michigan. In Tennessee, the highway is paralleled by Interstate 24 all the way from Georgia to Kentucky, and I-24 has largely supplanted US-41 as a major highway, especially for large and heavy vehicles, such as tractor-trailer trucks and buses.
State Route 107 is a 78.77-mile (126.77 km) state highway in eastern Tennessee, United States. It begins at an intersection with Round Mountain Road south of Del Rio and ends at the North Carolina state line east of Unicoi, where it becomes NC 226.
U.S. Route 31A is a 76.94-mile-long (123.82 km) alternate route of U.S. Route 31 that exists between Nashville and Pulaski, Tennessee. It is located entirely in Middle Tennessee and except for the Lewisburg bypass, where it is concurrent with SR 106, it is entirely concurrent with unsigned State Route 11.
State Route 55 is an east–west highway in Middle Tennessee. The road begins at SR 50 in Lynchburg and ends at U.S. Route 70S and SR 380 in McMinnville. The current length is 49.3 mi (79.3 km). SR 55 heads northeast from Lynchburg to Tullahoma as a two-lane road. In Tullahoma, the route runs concurrent with US 41A. From here, SR 55 heads northeast as a multilane highway to Manchester, where it intersects US 41 and Interstate 24 (I-24). The route continues northeast, serving Summitville and Morrison before it reaches McMinnville.
State Route 50 (SR 50) is a west–to–east highway in Middle Tennessee. The road begins near Only and ends in Altamont. The current length is 161.3 miles (259.6 km).
U.S. Route 231 in Tennessee runs north–south for 121.15 miles (194.97 km), entirely in Middle Tennessee, that starts south of Fayetteville at the Alabama state line, and ends north of Westmoreland at the Kentucky state line. For the majority of its length, between the Alabama state line and Trousdale County, it is concurrent with unsigned State Route 10.
State Route 82 is a secondary state highway that runs through Moore and Bedford counties in south central Tennessee in the United States. The route runs from an intersection with SR 55 in Lynchburg north and east to SR 64 near Beech Grove.
U.S. Route 41 Alternate, also signed U.S. Route 41A in Tennessee (US 41A), connects the town of Monteagle, Tennessee, with Hopkinsville, Kentucky, 10 miles (16 km) north of the Tennessee line. It serves the city of Clarksville, Tennessee, on its way to Nashville, where it briefly runs concurrently with US 41. It then separates again to serve Shelbyville, Winchester, and Tullahoma before rejoining the main route atop Monteagle Mountain. US 41A runs west of US 41 for its entire length, aside from one mile in downtown Nashville where they are concurrent. US 41A is also concurrent with U.S. Route 31A from Nashville to Triune, Tennessee, for a distance of approximately 25 miles (40 km).
State Route 130 is 51.3-mile long east–west state highway in Middle Tennessee.
State Route 269 is a 49.2 miles (79.2 km) long east-west state highway in central Middle Tennessee.
SR 79 at the Alabama State Line
US 64 near Winchester 
US 41A / SR 50 in Winchester 
US 231 in Shelbyville 
